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100-63-0
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关键词:'100-63-0'
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Nikolay K Popnikolov et al.
American journal of clinical pathology, 120(2), 161-167 (2003-08-23)
We immunohistochemically compared benign myoepithelial tumors (adenomyoepitheliomas [AMEs]) and metaplastic matrix-producing (MMP-CA) and spindle cell (MSC-CA) carcinomas of the breast to identify helpful diagnostic markers. Normal myoepithelial cells (MECs) consistently expressed cytokeratin, alpha-smooth muscle actin (SMA), myosin, S-100, CD10, and
G R Gibbons et al.
Carcinogenesis, 12(12), 2253-2257 (1991-12-01)
L1210 cell lines have been described that are sensitive to most platinum compounds (L1210/0), resistant to ethylenediamine (en)-Pt but sensitive to diaminocyclohexane (dach)-Pt (L1210/DDP), and resistant to dach-Pt but sensitive to en-Pt (L1210/DACH). We have examined the effect of the
Meng Lu et al.
Die Pharmazie, 70(6), 388-393 (2015-07-21)
Ampelopsin (AMP), a novel flavonoid, has been shown to effectively inhibit the proliferation and induce apoptosis of some prostate cancer and breast cancer cell lines. Whether AMP has chemopreventive effects on the cell growth and apoptosis of human osteosarcoma MG-63
P C Chan et al.
Japanese journal of cancer research : Gann, 83(3), 258-263 (1992-03-01)
Short-term and long-term carcinogenicity of methyl carbamate (MCB) was evaluated in F344 rats and B6C3F1 mice. In experiments lasting 6, 12, and 18 months, MCB was given in water by gavage to groups of 10 male and 10 female rats
Kanako Takahashi et al.
International journal of molecular sciences, 24(16) (2023-08-26)
Human induced pluripotent stem cell (hiPSC)-derived neural cells have started to be used in safety/toxicity tests at the preclinical stage of drug development. As previously reported, hiPSC-derived neurons exhibit greater tolerance to excitotoxicity than those of primary cultures of rodent
Kevin B Long et al.
The American journal of surgical pathology, 34(5), 723-729 (2010-04-24)
PAX (paired box) genes encode a family of transcription factors that regulate organogenesis and cell-lineage specification in multiple organ systems. In the pancreas, PAX proteins play a critical role in islet cell differentiation. We recently observed that islet cells show
C H Huang et al.
Materials science & engineering. C, Materials for biological applications, 33(7), 4183-4187 (2013-08-06)
The bio-electrochemical response in simulated body fluid of the Zr53Cu30Ni9Al8 metallic glasses with different degrees of partial crystallization was systematically examined and discussed. Through thermal annealing, the volume fractions of the crystalline phases are determined to be 0, 34, 63
R T Pate et al.
Journal of dairy science, 101(9), 8532-8543 (2018-06-25)
Trace minerals are vital in the antioxidant response during oxidative stress; however, limited research is available on the effects of trace mineral supplementation during an aflatoxin (AF) challenge. The objective of the study was to determine the effects of 2
Liqin Jiang et al.
Investigative ophthalmology & visual science, 55(11), 7508-7519 (2014-10-02)
Disruption of dopaminergic signaling has been implicated in the abnormalities of ocular development in albinism, and many experiments have shown that retinal dopamine is a major regulator of postnatal eye growth and myopia in animal models. Therefore, in the present
Jing Chen et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(19), 3363-3367 (2014-01-16)
The study aimed to develop the assay of chrysosplenetin (CHR), a metabolic inhibitor of artemisinin by UPLC-MS/MS in rat plasma and investigate the pharmacokinetics parameters of CHR. The plasma samples were precipitated by acetonitrile to remove the proteins. Separation was
J T YaDeau et al.
British journal of anaesthesia, 115(2), 285-293 (2015-07-15)
Pregabalin may reduce postoperative pain and opioid use. Higher doses may be more effective, but may cause sedation and confusion. This prospective, randomized, blinded, placebo-controlled study tested the hypothesis that pregabalin reduces pain at 2 weeks after total knee arthroplasty
E J Love et al.
The Veterinary record, 172(24), 635-635 (2013-06-06)
Buprenorphine has recently obtained UK Marketing Authorisation for horses. The analgesic effects are long lasting, and have considerable potential for postoperative pain relief. This observer blinded, randomised study aimed to evaluate postsurgical analgesia in ponies premedicated with buprenorphine prior to
Hang Lin et al.
Journal of receptor and signal transduction research, 40(1), 49-57 (2020-01-18)
Background: Osteosarcoma is a highly malignant primary tumor. Baicalein has broad-spectrum anti-tumor effects. This study aimed to study the specific molecular regulatory mechanism of baicalein in anti-osteosarcoma and the possible regulatory signaling network involved.Methods: In vitro experiment, MG-63 cells treated
Laiju Kuzhuppillymyal-Prabhakarankutty et al.
World journal of microbiology & biotechnology, 36(3), 47-47 (2020-03-08)
Beauveria bassiana (Bals.) Vuillemin (B. bassiana) is an entomopathogenic fungus that establishes endophytic symbiosis with plants. In the present study, the effects of B. bassiana strains colonization in growing Zea mays L. (Z. mays), crop production, and drought tolerance were evaluated.
Dong H Sinn et al.
Journal of gastroenterology and hepatology, 26(9), 1374-1379 (2011-04-20)
A single nucleotide polymorphism near the interleukin-28B (IL28B) gene has been shown to predict hepatitis C virus (HCV) treatment response. We aim to determine the role of the IL28B genotype in Asian patients. A total of 118 patients (all Korean
Yun Xie et al.
Asian journal of andrology, 22(2), 184-191 (2019-06-13)
An ideal animal model of azoospermia would be a powerful tool for the evaluation of spermatogonial stem cell (SSC) transplantation. Busulfan has been commonly used to develop such a model, but 30%-87% of mice die when administered an intraperitoneal injection
Douglas H Ross et al.
Parasites & vectors, 5, 192-192 (2012-09-11)
Cat fleas, Ctenocephalides felis, are one of the most common ectoparasites infesting dogs and their environments. This study evaluated the efficacy of imidacloprid + pyriproxyfen (PPF) (Advantage® II for Dogs) and spinosad (Comfortis®) against established C. felis populations in dogs' simulated home
Molebogeng X Rangaka et al.
Lancet (London, England), 384(9944), 682-690 (2014-05-20)
Antiretroviral therapy reduces the risk of tuberculosis, but tuberculosis is more common in people with HIV than in people without HIV. We aimed to assess the effect of isoniazid preventive therapy on the risk of tuberculosis in people infected with
M Robinson et al.
Cancer letters, 48(3), 197-203 (1989-12-01)
Several chlorinated acetones have been identified in drinking water and these, as well as a number of chlorinated acroleins, are produced by chlorination of humic acid solutions. Many of these chlorinated compounds and the brominated acrolein analog were positive in
C R Reinemeyer et al.
Journal of the American Veterinary Medical Association, 206(11), 1710-1715 (1995-06-01)
Forty 11- to 12-week-old helminth-naive Beagles were categorized by sex and weight and randomly assigned to 4 treatment groups (group 1, ivermectin/pyrantel pamoate; group 2, milbemycin oxime; group 3, untreated control; group 4, diethylcarbamazine/oxibendazole). Each pup was inoculated PO with
G M Brodeur et al.
Science (New York, N.Y.), 224(4653), 1121-1124 (1984-06-08)
A domain of DNA designated N-myc is amplified 20- to 140-fold in human neuroblastoma cell lines but not in cell lines from other tumor types. N-myc has now been found to be amplified in neuroblastoma tissue from 24 of 63
G M Brodeur et al.
Science (New York, N.Y.), 224(4653), 1121-1124 (1984-06-08)
A domain of DNA designated N-myc is amplified 20- to 140-fold in human neuroblastoma cell lines but not in cell lines from other tumor types. N-myc has now been found to be amplified in neuroblastoma tissue from 24 of 63
Lei Gao et al.
The Lancet. Infectious diseases, 17(10), 1053-1061 (2017-07-19)
The management of latent Mycobacterium tuberculosis infection is a new priority action for the WHO End Tuberculosis (TB) Strategy. However, national guidelines on latent tuberculosis infection testing and treatment have not yet been developed in China. Here, we present the
A A A Jacobs et al.
Animal : an international journal of animal bioscience, 7(9), 1508-1516 (2013-04-20)
Stearoyl-CoA desaturase (SCD) in the bovine mammary gland introduces a cis-double bond at the Δ9 position in a wide range of fatty acids (FA). Several long-chain polyunsaturated fatty acids (PUFA) inhibit expression of SCD, but information on the effect of
L L Siu et al.
Investigational new drugs, 16(2), 113-119 (1998-12-16)
The anti-proliferative effects of pivaloyloxymethyl butyrate (AN-9), a butyric acid (BA) derivative with potent tumor-differentiating properties both in vitro and in vivo, was evaluated against colorectal, breast, lung, ovarian, renal cell, bladder, and other types of tumor colony-forming units in
Brian P Enright et al.
Birth defects research. Part B, Developmental and reproductive toxicology, 95(6), 431-443 (2012-12-06)
ABT-874 is an anti-IL-12/23 monoclonal antibody that binds to the p40 subunit of human IL-12 and IL-23. As part of its preclinical safety assessment, studies were conducted to assess its potential effects on pre- and postnatal development in cynomolgus monkeys.
Gian Luca Di Tanna et al.
The Lancet. Global health, 7(2), e191-e199 (2019-01-27)
Xpert MTB/RIF, the most widely used automated nucleic acid amplification test for tuberculosis, is available in more than 130 countries. Although diagnostic accuracy is well documented, anticipated improvements in patient outcomes have not been clearly identified. We performed an individual
Jarmila Sulcová et al.
Clinical chemistry and laboratory medicine, 43(2), 221-227 (2005-04-22)
Twenty-one healthy male volunteers aged 20-70 years were given transdermally 25 mg of 7-oxo-dehydroepiandrosterone daily in the form of an emulgel for 8 consecutive days. Morning blood was collected as follows: before application, and after the first, fourth and eighth
Ingrid Anna Maria Magnet et al.
Shock (Augusta, Ga.), 48(6), 674-680 (2017-06-01)
Extracorporeal life support (ECLS) for cardiopulmonary resuscitation (CPR) may increase end organ perfusion and thus survival when conventional CPR fails. The aim was to investigate, if after ventricular fibrillation cardiac arrest in rodents ECLS improves outcome compared with conventional CPR.
Analysis of morphine in serum by high performance liquid chromatography with amperometric detection.
H Vandenberghe et al.
Therapeutic drug monitoring, 4(3), 307-314 (1982-01-01)
In this report we describe a rapid and sensitive micromethod using high performance liquid chromatography (HPLC) with electrochemical detection (ED) to measure morphine concentration in serum or plasma. The separation of morphine and the internal standard 5-hydroxyquinoline, from interfering compounds
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