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关键词:'100-75-4'
显示 1-30 共 572 条结果 关于 "100-75-4" 范围 论文
Mark Ulrich Gerbershagen et al.
Anesthesia and analgesia, 101(3), 710-714 (2005-08-24)
In this study we evaluated the in vitro effects of 4-chloro-3-ethylphenol (CEP) using cumulative (12.5-200 micromol/L) or bolus (75 and 100 micromol/L) administrations, on muscle specimens from malignant hyperthermia (MH) susceptible and MH nonsusceptible patients, respectively. In the cumulative CEP
O G Gribakina et al.
Eksperimental'naia i klinicheskaia farmakologiia, 76(3), 35-37 (2013-06-19)
The influence of afobazole on isoenzyme CYP2C9 production in rats was studied using losartan as the marker drug. Single dose of losartan was administered orally without afobazole in a dose of 30 mg/kg and in the same single (30 mg/kg)
Zheng-Ming Ding et al.
The Journal of pharmacology and experimental therapeutics, 340(1), 202-209 (2011-10-21)
Ethanol (EtOH) and cocaine are both self-administered into the posterior ventral tegmental area (VTA). Self-administration of either drug is prevented by coadministration of a serotonin (5-HT₃) receptor antagonist. Electrophysiological studies indicated that cocaine and EtOH can act synergistically to stimulate
Seda Cetinkaya Karabekir et al.
Iranian journal of basic medical sciences, 23(1), 71-78 (2020-05-15)
Resveratrol (RSV) is a naturally occurring plant polyphenol with cardioprotective, neuroprotective, immunoregulatory, and anticancer properties and is biologically effective against various diseases. This study aimed to investigate the chemopreventive effect of different doses of RSV against hepatocellular carcinoma (HCC) induced
T Sahlu et al.
Journal of animal science, 73(1), 172-176 (1995-01-01)
Sixteen growing Alpine wethers (average BW 35 +/- 2 kg) were assigned to one of four treatments to evaluate tissue retention of the leucaena toxins mimosine (MIM) and 2,3-dihydroxypyridine (2,3-DHP). Treatments were infused i.v. for 2 d and were 1)
Bao-hua Yu et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 38(1), 35-41 (2009-06-06)
(1) To investigate the activation of AKT/mTOR signaling transduction pathway in DLBCL and its association with the expression of bcl-6 and some other clinical pathologic factors. (2) To estimation of the signaling pathway function in diverse subtypes of DLBCL and
J P Seiler
Carcinogenesis, 6(12), 1811-1813 (1985-12-01)
The results of Salmonella mutagenicity tests with the herbicide nitrofen (2,4-dichlorophenyl-4-nitrophenyl ether, CAS 1836-75-5) reported in the literature seem to vary according to source or lot of the technical product. This behaviour could be reproduced in our experiments, and it
Andrew Emmanuel et al.
International journal of colorectal disease, 34(5), 829-836 (2019-02-21)
Almost any colorectal superficial neoplastic lesion can be treated by endoscopic resection (ER) but very little is known about outcomes of ER leaving circumferential or near-circumferential mucosal defects. We report the outcomes of ER leaving ≥ 75% circumferential mucosal defects performed
J Pinski et al.
International journal of peptide and protein research, 45(5), 410-417 (1995-05-01)
The objective of this study was to examine the in vivo and in vitro gonadotropin-inhibiting potencies, edematogenic activities and the receptor binding affinities of the D-Cit6, D,L-Cit6 and L-Cit6 forms of the LH-RH antagonist Cetrorelix (SB-75) [Ac-D-Nal(2)1,D-Phe(4Cl)2,D-Pal(3)3,D-Cit6,D-Ala10]LH- RH. In order
Josep Bassaganya-Riera et al.
The Journal of nutrition, 141(7), 1318-1325 (2011-05-13)
Our goal in this study was to determine the potential for dietary fibers to prevent gut inflammation in IL-10-deficient (IL-10(-/-)) mice. C57BL/6J wild-type (WT) mice (n = 90) and IL-10(-/-) mice (n = 185) were assigned to a control diet
T Yano et al.
Proceedings of the National Academy of Sciences of the United States of America, 91(15), 7090-7094 (1994-07-19)
Female athymic nude mice bearing xenografts of OV-1063 human epithelial ovarian cancer cell line were treated with potent luteinizing hormone (LH)-releasing hormone (LH-RH) antagonist SB-75 (Cetrorelix; [Ac-D-Nal(2)1, D-Phe(4 CI)2, D-Pal(3)3, D-Cit6, D-Ala10]LH-RH in which Ac-D-Nal(2) = N-acetyl-3-(2-naphthyl)-D-alanine, D-Phe(4CI) = 4-chloro-D-phenylalanine
K Hanew et al.
European journal of endocrinology, 134(1), 67-72 (1996-01-01)
The effect of GHRH-antagonist [(N-Ac-Tyr1, D-Arg2) GRF-(1-29)-NH2] on plasma GH morning and evening secretion was evaluated in 14 normal subjects (10 males, 4 females, aged 19-25 years). Plasma GH was determined using a high sensitivity IRMA kit (detection limit, 0.006
Cody C Wyles et al.
Clinical orthopaedics and related research, 473(3), 1155-1164 (2014-09-05)
Corticosteroids are a common, short-term, local antiinflammatory and analgesic for treating patients with musculoskeletal disorders. Studies have shown the deleterious effects of corticosteroids on chondrocytes, suggesting a potentiation of degenerative joint disease. Mesenchymal stem cells (MSCs) are the direct progenitors
Sarika Jain et al.
The American journal of surgical pathology, 37(12), 1824-1830 (2013-11-15)
Chromophobe renal cell carcinoma (ChRCC) and oncocytoma present with a perplexing overlap of morphologic and immunohistochemical features. ChRCC have deletions in the 1p21.1 region including the amylase α-1A gene (AMY1A). No such deletions are found in oncocytoma. Instead, oncocytomas shared
Anjali Pandey et al.
Journal of medicinal chemistry, 45(17), 3772-3793 (2002-08-09)
We have previously found that the 4-[4-(N-substituted carbamoyl)-1-piperazinyl]-6,7-dimethoxyquinazolines can function as potent and selective inhibitors of platelet-derived growth factor receptor (PDGFR) phosphorylation. A series of highly potent, specific, orally active, small molecule kinase inhibitors directed against members of PDGFR receptor
M U Gerbershagen et al.
Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 39(2), 81-86 (2004-02-10)
The diagnosis of malignant hyperthermia is currently performed with the in-vitro contracture test (IVCT) with halothane and caffeine. This test has a sensitivity of 99.0 % but only a specificity of 93.6 %. A cumulative IVCT with 4-chloro-3-ethyl-phenole (CEP) has
Alex E Cook et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 36(10), 2657-2663 (2018-05-11)
This study was designed to characterize metabolic responses of meniscal tissue explants to injury and inflammation. We hypothesized that impact injury and interleukin (IL-1β) stimulation of meniscal explants would result in significant increases in matrix metalloproteinase (MMP) activity and relevant
Søren Langkilde et al.
Journal of agricultural and food chemistry, 56(18), 8753-8760 (2008-08-20)
Sprouted, stressed, or spoiled potato tubers have reportedly led to human acute intoxication, coma, and death when consumed in high amounts. These effects have been attributed to glycoalkaloids (GAs), primarily alpha-solanine and alpha-chaconine, naturally present in all potatoes. The level
U D Kuhn et al.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 50(4-6), 491-496 (1998-10-23)
7-Ethoxycoumarin (EC) is widely used as a model substrate for monooxygenase function, its O-deethylation representing cytochrome P450 (P450) activity mainly of 1A but also of 2B isoforms. Reports on investigations of its own capacity to induce or suppress P450 activities
Xavier Barceló et al.
Biomedicines, 10(7) (2022-07-28)
Negative foreign body responses following the in vivo implantation of bioprinted implants motivate the development of novel bioinks which can rapidly degrade with the formation of functional tissue, whilst still maintaining desired shapes post-printing. Here, we investigated the oxidation of
Beenish Israr et al.
Food chemistry, 141(3), 1690-1693 (2013-07-23)
Phytate and mineral cations are both considered as important dietary factors for inhibiting the crystallisation of calcium oxalate kidney stones in susceptible individuals. In this paper, the phytate and mineral composition of whole bran cereals (wheat, barley and oat) and
Miriam H Inoue et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 44(8), 757-763 (2010-02-26)
This research was aimed at understanding the dynamics of the herbicides diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea], imazapic [2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-5-methylnicotinic acid] and isoxaflutole [5-cyclopropyl-4-(2-methanesulfonyl-4-trifluoromethyl benzoyl)isoxazole] in two soils of different physico-chemical properties. To accomplish such intent, several greenhouse experiments were run. The bioavailability of diuron
J Horvath et al.
International journal of oncology, 6(5), 969-975 (1995-05-01)
The effects of luteinizing hormone-releasing hormone (LH-RH), and LH-RH antagonist Cetrorelix, (SB-75, [Ac-D-Nal(2)(1),D-Phe(4-Cl)(2),D-Pal(3)(3),D-Cit(6),D-Ala(10)]LH-RH) on cell growth and the production of hCG and cAMP in JAR human choriocarcinoma cells were examined in vitro. Both LH-RH and its antagonist SE-75, at 1
Ashley Cimino-Mathews et al.
Human pathology, 44(6), 959-965 (2012-12-25)
The transcription factor Sox10 mediates the differentiation of neural crest-derived cells, and Sox10 labeling by immunohistochemistry (IHC) is used clinically primarily to support the diagnosis of melanoma. Sox10 expression by IHC has been previously documented in benign breast myoepithelial cells
Yusuke Oji et al.
Cancer science, 94(6), 523-529 (2003-06-26)
The expression levels of the Wilms' tumor gene WT1 were examined in 56 cases of head and neck squamous cell carcinoma (HNSCC) using quantitative real-time reverse transcriptase-polymerase chain reaction (RT-PCR). They included 4 cases of floor of mouth, 9 of
Morteza Zendehdel et al.
Neuroscience letters, 739, 135408-135408 (2020-10-08)
The aim of the current study was to determine effects of intracerebroventricular (ICV) and intraperitoneal (i.p.) administration of Methylamine (MET) and possible interactions with nitric oxide (NO) and TAAR1 pathways in 24-h fasted (FD24) and ad libitum layer-type chicken. In
Maryna Petrushko et al.
Zygote (Cambridge, England), 27(6), 386-391 (2019-08-16)
The complexity of predicting embryo development potential at the cleavage stages and the emergence of epigenetic risks during prolonged in vitro culture of pre-implantation embryos made it more advantageous to transfer embryos at the morula stage to the uterine cavity.
Hani Hosseinifar et al.
Journal of assisted reproduction and genetics, 31(12), 1681-1685 (2014-10-11)
To find a relationship between absence of annulus and asthenozoospermia in Iranian men. In the present study, semen samples from 100 asthenozoospermic and 20 normozospermic patients were analyzed for sperm concentration and motility. Spermatozoa were immunostained for the two septin
Farouk Jaber et al.
Analytical and bioanalytical chemistry, 387(7), 2527-2535 (2007-01-30)
Solid-phase microextraction (SPME) coupled with gas chromatography-mass spectrometry has been used for analysis of four phenols and sixteen nitrophenols in rainwater samples. Analytes were extracted from the water in the immersion mode and derivatised for 5 min during direct desorption
Akiho Okada et al.
Gan to kagaku ryoho. Cancer & chemotherapy, 40(11), 1541-1544 (2013-11-16)
A 75-year-old man who complained of upper abdominal discomfort was diagnosed with primary duodenal cancer. The patient was treated with a pancreaticoduodenectomy, ascending colectomy and postoperative chemotherapy of S-1 and irinotecan[IRIS; S-1, 80mg/m2(days 1-14); irinotecan, 100 mg/m2(days 1 and 15
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