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关键词:'101-37-1'
显示 1-30 共 43 条结果 关于 "101-37-1" 范围 论文
Guiying Zhang et al.
Current pharmaceutical biotechnology, 16(2), 187-193 (2014-11-14)
In this study, sustained-release of GnRH antagonist peptide LXT-101 was realized through oil formulation, and their releasing characteristics in vitro and in vivo were investigated. In this formulation, the static interaction between cationic charged peptide LXT-101 and the negative charged
Tsuguhito Ota et al.
Diabetes research and clinical practice, 67(1), 63-69 (2004-12-29)
To investigate the presence and level of serum antibodies to IA-2 (IA-2A) in Japanese patients with adult type 1 diabetes in order to clarify its association with glutamic acid decarboxylase (GAD) antibody. Serum samples were obtained from 101 Japanese patients
Makoto Suzuki et al.
Cancer letters, 242(2), 222-230 (2006-02-07)
We investigated aberrant methylation in 101 prostate cancers(PCa) and 32 histologically normal prostate tissues. We focused on genes largely in the apoptotic pathway. Methylation frequencies of the genes were Reprimo, 54%; TMS1, 47%; DcR1, 45%; RRAD, 37%; DcR2, 37%; CRBP1
V Castronovo et al.
The Journal of biological chemistry, 266(30), 20440-20446 (1991-10-25)
We report the characterization of two functional domains of the metastasis-associated 67-kDa laminin receptor (67-LR). Using synthetic peptides deduced from the cDNA sequence of the 37-kDa precursor of the laminin receptor (37-LRP) as well as their corresponding affinity-purified polyclonal antibodies
D J McCarthy et al.
Mutation research, 119(1), 7-14 (1983-01-01)
The mutagenicity of 4,4'-bis(dimethylamino)benzophenone (Michler's ketone, MK, CAS No. 90-94-8) and 4,4'-methylenebis(N,N-dimethyl)benzamine (reduced Michler's ketone, RMK, CAS No. 101-61-1) for Salmonella typhimurium strain TA100 was compared using activated 9000 X g (S9) liver supernatants from 2 animal species. RMK, but
R Hui et al.
Annals of oncology : official journal of the European Society for Medical Oncology, 28(4), 874-881 (2017-02-09)
Pembrolizumab improved survival as first- and second-line therapy compared with chemotherapy in patients with highly programmed death ligand 1 (PD-L1) expressing advanced non-small cell lung cancer (NSCLC). We report the long-term safety and clinical activity of pembrolizumab as first-line therapy
Giuseppe M V Barbagallo et al.
Neurosurgical focus, 37(6), E4-E4 (2014-12-02)
The objective of this study was to report the authors' experience with the long-term administration of temozolomide (TMZ; > 6 cycles, up to 101) in patients with newly diagnosed glioblastoma and to analyze its feasibility and safety as well as
N Umeda et al.
Clinical and experimental immunology, 172(1), 44-53 (2013-03-14)
To identify and characterize anti-citrullinated glucose-6-phosphate isomerase (GPI) peptide antibodies in patients with rheumatoid arthritis (RA). Nine GPI arginine-bearing peptides in human GPI protein were selected and cyclic citrullinated GPI peptides (CCG-1-9) were constructed. Samples were obtained from RA (n = 208)
B Subramanian
Journal of nanoscience and nanotechnology, 13(7), 4565-4572 (2013-08-02)
Titanium nitride (TiN)/niobium nitride (NbN) nanostructured multilayer coatings were prepared by DC reactive magnetron sputtering method using the combination of a titanium and niobium target and an Ar-N2 mixture discharge gas on to 316L stainless steel substrates. The coatings showed
Daniela Accorsi-Mendonça et al.
Journal of neurophysiology, 121(5), 1822-1830 (2019-03-21)
Sustained hypoxia (SH) activates chemoreceptors to produce cardiovascular and respiratory responses to bring the arterial partial pressure of O2 back to the physiological range. We evaluated the effect of SH (fraction of inspired O2 = 0.10, 24 h) on glutamatergic synaptic transmission
Patrick Vourc'h et al.
Neuroscience letters, 338(2), 115-118 (2003-02-05)
We previously observed in four autistic patients a new allele (GXAlu 5) of the GXAlu microsatellite marker located in intron 27b of the neurofibromatosis type 1 (NF1) gene (17q11.2). This large intron contains the OMGP gene, coding for the oligodendrocyte
C A Abbott et al.
Clinical science (London, England : 1979), 85(1), 77-81 (1993-07-01)
1. The activity of serum butyrylcholinesterase ('pseudocholinesterase', EC3.1.1.8) was investigated in 56 patients with type 1 diabetes mellitus, 51 patients with type 2 diabetes mellitus and 101 healthy control subjects. 2. Butyrylcholinesterase activity was significantly elevated in both type 1
Suk Kyeong Kim et al.
Thyroid : official journal of the American Thyroid Association, 19(2), 137-141 (2008-11-19)
It has been reported that patients with papillary thyroid carcinoma (PTC) have a high incidence of background Hashimoto thyroiditis (HT); however, the linkage of HT to PTC is controversial. Recent studies have shown that the prevalence of activating point mutations
J D Weber et al.
Molecular and cellular biology, 20(7), 2517-2528 (2000-03-14)
The ARF tumor suppressor protein stabilizes p53 by antagonizing its negative regulator, Mdm2 (Hdm2 in humans). Both mouse p19(ARF) and human p14(ARF) bind to the central region of Mdm2 (residues 210 to 304), a segment that does not overlap with
Sara M Ø Solbak et al.
Biochimica et biophysica acta, 1824(4), 667-678 (2012-02-22)
The 52-amino acid human immunodeficiency virus type 1 (HIV-1) p6 protein has previously been recognized as a docking site for several cellular and viral binding factors and is important for the formation of infectious viruses. A particular structural feature of
Silvana Aparecida Alves Corrêa et al.
Journal of the renin-angiotensin-aldosterone system : JRAAS, 10(1), 51-58 (2009-03-17)
We evaluated the association between components of the renin-angiotensin system and the development of breast cancer in a case-control study by means of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) and angiotensin II type 1 (AT( 1))-receptor A1166C polymorphisms. Genotyping was performed
Silvia Pérez-Pérez et al.
Frontiers in immunology, 12, 798003-798003 (2021-12-17)
Human endogenous retrovirus W family envelope proteins (pHERV-W ENV/syncytin-1) have been repeatedly associated with multiple sclerosis (MS). Here, we have focused on the study of pHERV-W ENV/syncytin-1 expression levels in MS patients (relapsing and progressive forms) and in healthy donors
Sylvie Di Filippo et al.
Human immunology, 66(2), 133-139 (2005-02-08)
Late renal dysfunction may affect long-term outcome of nonrenal transplant recipients. We hypothesized that transforming growth factor beta1 (TGFbeta1) might play a role in the fibrogenic mechanisms leading to renal dysfunction. The aim was to determine whether TGFbeta1 gene polymorphisms
Ruben Lopez-Benitez et al.
Cardiovascular and interventional radiology, 40(8), 1246-1254 (2017-03-21)
In vitro and in vivo evaluation of fast- and slow-release gemcitabine-eluting hydrogel (GEH) devices. For in vitro elution, the GEH devices were placed in phosphate-buffered saline at 37 °C. Periodically, the solution was analyzed for gemcitabine. The devices consisting of fast
M B Sukkar et al.
The European respiratory journal, 39(3), 721-729 (2011-09-17)
The receptor for advanced glycation end-products (RAGE) is a pattern-recognition receptor involved in the host response to injury, infection and inflammation. It is a membrane receptor, but also has soluble forms (sRAGE). Deficiencies in sRAGE are linked to heightened inflammation
Aida Kiviniemi et al.
Oncotarget, 8(30), 49123-49132 (2017-05-04)
Somatostatin receptor subtype 2A (SSTR2A) is a potential therapeutic target in gliomas. Data on SSTR2A expression in different glioma entities, however, is particularly conflicting. Our objective was to characterize SSTR2A status and explore its impact on survival in gliomas classified
The endothelin-1 G5665T polymorphism impacts transplant-free survival for single ventricle patients.
Paul M Kirshbom et al.
The Journal of thoracic and cardiovascular surgery, 136(1), 117-122 (2008-07-08)
Early survival for children with single-ventricle congenital heart disease has improved, but late attrition remains a serious problem. The endothelin-1 G5665T single nucleotide polymorphism has been linked to increased vascular reactivity and hypertension. The goal of this study was to
Liaman K Mamedova et al.
Biochemical pharmacology, 67(9), 1763-1770 (2004-04-15)
The physiological role of the P2Y(6) nucleotide receptor may involve cardiovascular, immune and digestive functions based on the receptor tissue distribution, and selective antagonists for this receptor are lacking. We have synthesized a series of symmetric aryl diisothiocyanate derivatives and
Nithyanand Paramasivam et al.
International journal of systematic and evolutionary microbiology, 63(Pt 5), 1880-1884 (2012-09-25)
A marine bacterial strain, designated MD2(T), was isolated from the damaged tissue of a hydrocoral, Millepora dichotoma, collected from the coral reef in the northern Red Sea, Gulf of Eilat, Israel. Strain MD2(T) was Gram-reaction-negative, rod-shaped and motile, and formed
W Shen et al.
Human & experimental toxicology, 15(5), 428-434 (1996-05-01)
1. Nitrofurantoin is an antimicrobial agent which produces hepatotoxicity caused by the redox cycling of the nitro group and its radical anion. This futile cycling triggers a complex series of events known collectively as oxidative stress. 2. Our goal was
Bert-Jan H van den Born et al.
Journal of hypertension, 25(11), 2227-2233 (2007-10-09)
Malignant hypertension can be considered an extreme phenotype of renin-mediated hypertension. Therefore, we compared the allelic frequencies of the angiotensinogen (AGT) M235T, angiotensin-converting enzyme insertion/deletion (ACE I/D) and angiotensin II-type I receptor (AT1R) A1166C polymorphisms in malignant hypertensive patients with
Rui Sun et al.
The Journal of biological chemistry, 294(31), 11840-11852 (2019-06-16)
Eukaryotic translation initiation factor 4E (eIF4E)-binding protein 1 (4E-BP1) inhibits cap-dependent translation in eukaryotes by competing with eIF4G for an interaction with eIF4E. Phosphorylation at Ser-83 of 4E-BP1 occurs during mitosis through the activity of cyclin-dependent kinase 1 (CDK1)/cyclin B
Matthew H Kulke et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 15(1), 338-345 (2009-01-02)
Recent studies suggest that temozolomide has activity in neuroendocrine tumors. Low levels of the DNA repair enzyme, O(6)-methylguanine DNA methyltransferase (MGMT), are associated with sensitivity to temozolomide in other tumor types. We evaluated the prevalence of MGMT deficiency in neuroendocrine
Madhavi Sekharam et al.
Anticancer research, 23(2B), 1517-1524 (2003-06-25)
Colorectal carcinomas have been found to express increased levels of IGF1 and IGF1-R, as compared to normal or adenomatous colonic mucosa, and it has been postulated that a subset of colorectal cancers are under the autocrine regulation of the IGF1/IGF1-R
Letizia Rasica et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 315(3), R453-R460 (2018-04-26)
Previous studies showed a higher O2 cost of exercise, and therefore, a reduced exercise tolerance in patients with obesity during constant work rate (CWR) exercise compared with healthy subjects. Among the ergogenic effects of dietary nitrate ([Formula: see text]) supplementation
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