101530-10-3

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关键词:'101530-10-3'

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Antifungal activity of the new agent latoconazole in two tinea models.

T Ohmi et al.

Arzneimittel-Forschung, 41(8), 847-851 (1991-08-01)

In vitro and in vivo antifungal activities of the new imidazole derivative latoconazole ((+-)-(E)-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-1- imidazolylacetonitrile, NND-318; CAS 101530-10-3) were studied in comparison with three major topical agents, clotrimazole, bifonazole and tolnaftate. The in vitro activity of latoconazole against dermatophytes was

Wound healing effect of the new imidazole antimycotic lanoconazole in rats.

Y Niwano et al.

Arzneimittel-Forschung, 46(2), 218-223 (1996-02-01)

The wound healing effect of cream preparations of lanoconazole (CAS 101530-10-3, NND-318), an antimycotic imidazole compound, was examined using an excisional open skin-wound model produced on the back of rats. The rapid decrease in the size of wounded areas showed

Studies on the antifungal activity of the new imidazole antimycotic lanoconazole in infected sites. Distribution in the skin and in vitro activity in the presence of stratum corneum.

Y Niwano et al.

Arzneimittel-Forschung, 47(9), 1056-1060 (1997-10-29)

To answer the question why topically applied lanoconazole (CAS 101530-10-3, NND-318) is so highly effective in the treatment of dermatomycoses in both animal models and human patients, the antifungal activity of lanoconazole in infected sites was investigated. 1. Distribution of

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