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105-21-5
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关键词:'105-21-5'
显示 1-30 共 51 条结果 关于 "105-21-5" 范围 论文
M Hungs et al.
Neurology, 57(10), 1893-1895 (2001-11-28)
Human narcolepsy/cataplexy is associated with reduced hypocretin (orexin) transmission. A common preprophypocretin (HCRT) polymorphism (-909C/T) was identified and tested in 502 subjects (105 trio families, 80 Caucasian narcolepsy cases, and 107 Caucasian control subjects). This polymorphism was not associated with
Abbas Khani-Hanjani et al.
The Journal of rheumatology, 29(7), 1358-1365 (2002-07-26)
To examine the relationship between disease severity in patients with confirmed rheumatoid arthritis (RA) and the carriage of alleles expressing the high risk epitope (HRE) QK/QR/RRRAA or the low risk epitope (LRE) DERAA at positions 70-74 of the third hypervariable
Kathleen Campbell et al.
Hearing research, 282(1-2), 138-144 (2011-09-20)
We have previously reported rescue from noise-induced auditory brainstem response (ABR) threshold shifts with d-methionine (d-met) administration 1 h after noise exposure. The present study investigated further d-met rescue intervals at 3, 5 and 7 h post-noise exposure. Chinchillas laniger were exposed
T Lin et al.
Molecular genetics and metabolism, 64(1), 58-61 (1998-07-31)
Lowe syndrome (OCRL) is an X-linked disorder involving the eyes, kidney, and nervous system that is caused by loss of function in the OCRL1 gene. OCRL1 contains 24 exons (23 of which are coding) and encodes a 105-kDa enzyme with
Sri Wigati Mardi Mulyani et al.
Veterinary world, 11(7), 965-970 (2018-08-28)
To examine the effect of hypoxic preconditions on the ability of bone marrow stem cells culture mediated expression C-X-C chemokine receptor type 4 (CXCR4) and stromal cells derived factor-1 (SDF-1) in vitro. Bone marrow mesenchymal stem cells (BMSCs) were derived
E Goekkurt et al.
British journal of cancer, 94(2), 281-286 (2005-12-01)
To evaluate the predictive value of a panel of gene polymorphisms involved in metabolism of 5-FU and cisplatin on clinical outcome in advanced gastric cancer patients. A total of 52 patients were enrolled in this study. DNA was extracted from
Ivo Lovricević et al.
Collegium antropologicum, 28(2), 647-654 (2005-01-26)
5, 10-Methylenetetrahydrofolate Reductase (MTHFR) is one of the key enzymes in the metabolism of homocysteine, where it catalyses its remethylation. The autosomal recessive bp 677 C --> T mutation in the MTHFR gene leads to the substitution of valine for
Ryota Fujisawa et al.
BMC musculoskeletal disorders, 20(1), 316-316 (2019-07-08)
Synovial mesenchymal stem cells (MSCs) are an attractive cell source for cartilage and meniscus regeneration. The optimum cryopreservation medium has not been determined, but dimethylsulfoxide (DMSO) should be excluded, if possible, because of its toxicity. The purposes of our study
Lucía Gato-Calvo et al.
Current pharmaceutical biotechnology, 20(11), 920-933 (2019-06-27)
Platelet Rich Plasma (PRP) has recently emerged as a potential treatment for osteoarthritis (OA), but composition heterogeneity hampers comparison among studies, with the result that definite conclusions on its efficacy have not been reached. 1) To develop a novel methodology
Stephen Z Levine et al.
Schizophrenia research, 145(1-3), 125-127 (2013-02-12)
The treatment and measurement of negative symptoms are currently at issue in schizophrenia, but the clinical meaning of symptom severity and change is unclear. To offer a clinically meaningful interpretation of severity and change scores on the Scale for the
Natan D da Silva et al.
Genes, 14(1) (2023-01-22)
Patients with peripheral artery disease (PAD) have reduced muscle capillary density. Walking training (WT) is recommended for PAD patients. The goal of the study was to verify whether WT promotes angiogenesis in PAD-affected muscle and to investigate the possible role
F Röschenthaler et al.
European journal of immunology, 30(12), 3349-3354 (2000-11-28)
Five contigs of the 5' part of the immunoglobulin kappa locus (F. Röschenthaler et al., Eur. J. Immunol. 1999. 29: 2065 - 2071) have been linked by cosmid clones prepared from bacterial artificial chromosomes (BACs) and by PCR. One of
Prathik Roy et al.
Journal of hazardous materials, 243, 286-291 (2012-11-21)
We have developed a simple, colorimetric iron telluride (FeTe) nanorods (NRs) based system for the detection of mercury, mainly based on the cation exchange reaction between FeTe NRs and Hg(2+). FeTe NRs (length, 105 ± 21 nm) react with Hg(2+)
Anna Menoyo et al.
Cell biochemistry and function, 24(5), 381-385 (2005-09-01)
The CYP2D6 gene codes for a P450 monooxygenase which is involved in the biotransformation of a large number of commonly prescribed drugs. Adverse drug effects and therapeutic failure can be related to abnormal CYP2D6 activity. We investigated the allele and
Victoria E Sanchez et al.
Scientific reports, 10(1), 11003-11003 (2020-07-06)
Preclinical models that reliably recapitulate the immunosuppressive properties of human gliomas are essential to assess immune-based therapies. GL261 murine glioma cells are widely used as a syngeneic animal model of glioma, however, it has become common practice to transfect these
Kathryn Futrega et al.
Communications biology, 4(1), 29-29 (2021-01-06)
Virtually all bone marrow-derived stromal cell (BMSC) chondrogenic induction cultures include greater than 2 weeks exposure to transforming growth factor-β (TGF-β), but fail to generate cartilage-like tissue suitable for joint repair. Herein we used a micro-pellet model (5 × 103 BMSC each)
L A Diekman et al.
Immunohematology, 16(2), 74-77 (2004-09-18)
A reduced frequency of HLA-DQ6 in patients with a positive direct antiglobulin test (DAT) was previously reported but race was undisclosed. Therefore, we investigated a total of 275 patients (80 Caucasian, 113 African American, and 82 Mexican American) and 518
Y K Jung et al.
Molecular endocrinology (Baltimore, Md.), 5(9), 1257-1268 (1991-09-01)
Several genomic clones encoding carboxypeptidase-E (CPE) have been isolated and partially sequenced. Southern blot analysis indicates that a single copy of this gene is present in the rat genome. The entire gene spans approximately 50 kilobases and consists of nine
Thomas G Papathomas et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 28(6), 807-821 (2015-02-28)
Despite the established role of SDHB/SDHA immunohistochemistry as a valuable tool to identify patients at risk for familial succinate dehydrogenase-related pheochromocytoma/paraganglioma syndromes, the reproducibility of the assessment methods has not as yet been determined. The aim of this study was
P T Luik et al.
Diabetologia, 46(8), 1131-1139 (2003-07-12)
The renin-angiotensin-aldosterone system is important in diabetic nephropathy, with the angiotensin-converting-enzyme DD-genotype being a renal risk factor. The D-allele is associated with higher ACE concentrations, but functional consequences in diabetes mellitus are not known. To analyse these consequences, we assessed
Frank J Quayle et al.
Surgery, 142(6), 800-805 (2007-12-08)
The occurrence of pheochromocytoma in multiple endocrine neoplasia type 2A (MEN 2A) carriers varies greatly. This study aims to determine PC expression for specific MEN 2A RET mutations. Charts of MEN 2A patients enrolled in our multiple endocrine neoplasia program
Mark M Kushnir et al.
Clinical biochemistry, 37(5), 357-362 (2004-04-17)
Cortisol metabolism is controlled by 11beta-hydroxysteroid dehydrogenase (11beta-HSD) isoenzymes, which interconvert cortisol and cortisone. Accurate measurement of the cortisol and cortisone concentrations and their ratio provide useful information about 11beta-HSD activity. Cortisol and cortisone were extracted with methyl-tert-butyl ether from
L L Peters et al.
The Journal of cell biology, 130(2), 313-330 (1995-07-01)
We cloned a novel ankyrin, Ank3, from mouse kidney cDNA. The full-length transcript is predicted to encode a 214-kD protein containing an 89 kD, NH2 terminal "repeat" domain; a 65 kD, central "spectrin-binding" domain; and a 56 kD, COOH-terminal "regulatory"
Kostan W Reisinger et al.
Journal of pediatric gastroenterology and nutrition, 59(6), 720-724 (2014-08-12)
The incidence of necrotizing enterocolitis (NEC) is higher in formula-fed babies than in breast-fed babies, which may be caused by breast-feeding-induced gut maturation. The effect of breast-feeding on gut maturation has been widely studied in animal models. This study aimed
Andrea M Mobiglia et al.
Translational animal science, 5(3), txab119-txab119 (2021-10-22)
Two experiments were conducted to evaluate the effects of feed additives [monensin (MON); 30 mg/kg of dry matter (DM), and virginiamycin (VM); 25 mg/kg DM] and grain adaptation programs [adding roughage (ROU; sugarcane bagasse) or not (NO-ROU) during the 20-d
J A Ramos-Vara et al.
Veterinary pathology, 44(6), 875-884 (2007-11-28)
Multiple myeloma oncogene 1/interferon regulatory factor 4 (MUM1/IRF4) is involved in lymphoid cell differentiation, particularly in the production of plasma cells. We examined the immunoreactivity of mouse monoclonal antibody Mum-1p to MUM1/IRF4 and compared it with expression of CD79a and
V Soukup et al.
Urologia internationalis, 80(4), 413-418 (2008-07-01)
To evaluate the prognostic value of T1 subclassification and fascin-1 expression in T1 human urothelial cell carcinoma of the bladder. In a prospective study with 105 consecutive patients, T1 tumors were subclassified into 2 groups according to the depth of
Filip Janku et al.
PloS one, 6(7), e22769-e22769 (2011-08-11)
Oncogenic mutations of PIK3CA, RAS (KRAS, NRAS), and BRAF have been identified in various malignancies, and activate the PI3K/AKT/mTOR and RAS/RAF/MEK pathways, respectively. Both pathways are critical drivers of tumorigenesis. Tumor tissues from 504 patients with diverse cancers referred to
Hassen Hadj-Kacem et al.
Disease markers, 29(2), 63-69 (2010-11-04)
Deleterious mutations of SLC26A4 cause Pendred syndrome (PS), an autosomal recessive disorder comprising goitre and deafness with enlarged vestibular aqueducts (EVA), and nonsyndromic hearing loss (NSHL). However, the SLC26A4 hyperactivity was recently associated with the emergence of autoimmune thyroid diseases
P J Nicholls et al.
Journal of immunological methods, 165(1), 81-91 (1993-09-27)
Cloning the correct VL kappa gene from hybridomas derived from MOPC-21 can be problematic because such cell lines variably express a transcript which is aberrantly rearranged at the VJ recombination site. Cellular levels of the aberrant transcript can exceed that
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