105-41-9

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Lenacil degradation in the environment and its metabolism in the sugar beets.

M Zhang et al.

Journal of agricultural and food chemistry, 47(9), 3843-3849 (1999-12-20)

14C-Lenacil photolysis and hydrolysis studies were conducted at 2 ppm in sterilized buffers at pH 5, 7, and 9 for up to 15 and 30 days, respectively. The degradation of (14)C-lenacil in three soils and in two sediments systems was

Pheochromocytoma penetrance varies by RET mutation in MEN 2A.

Frank J Quayle et al.

Surgery, 142(6), 800-805 (2007-12-08)

The occurrence of pheochromocytoma in multiple endocrine neoplasia type 2A (MEN 2A) carriers varies greatly. This study aims to determine PC expression for specific MEN 2A RET mutations. Charts of MEN 2A patients enrolled in our multiple endocrine neoplasia program

Associations between glutathione S-transferase pi Ile105Val and glyoxylate aminotransferase Pro11Leu and Ile340Met polymorphisms and early-onset oxaliplatin-induced neuropathy.

Masashi Kanai et al.

Cancer epidemiology, 34(2), 189-193 (2010-03-24)

Although the risk of oxaliplatin-induced neuropathy depends on cumulative oxaliplatin dose, susceptibility to this adverse event differs greatly among patients. In this study, we investigated the associations between oxaliplatin-induced neuropathy and the following polymorphisms: glutathione S-transferase pi (GSTP1) Ile(105)Val, and

Analysis of the IDH1 codon 132 mutation in brain tumors.

Jörg Balss et al.

Acta neuropathologica, 116(6), 597-602 (2008-11-06)

A recent study reported on mutations in the active site of the isocitrate dehydrogenase (IDH1) gene in 12% of glioblastomas. All mutations detected resulted in an amino acid exchange in position 132. We analyzed the genomic region spanning wild type

Analysis of the IDH1 codon 132 mutation in brain tumors.

Jörg Balss et al.

Acta neuropathologica, 116(6), 597-602 (2008-11-06)

Familial dwarfism due to a novel mutation of the growth hormone-releasing hormone receptor gene.

R Salvatori et al.

The Journal of clinical endocrinology and metabolism, 84(3), 917-923 (1999-03-20)

Isolated growth hormone (GH) deficiency (IGHD) is a rare cause of short stature. The same mutation of the gene encoding the growth hormone-releasing hormone receptor (GHRHR) has been identified as the basis for IGHD in three families from the Indian

Comparison of drug eluting versus bare metal stents for pulmonary vein stenosis in childhood.

Asra Khan et al.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 94(2), 233-242 (2019-05-09)

Comparison of outcomes using bare metal (BMS) and drug-eluting (DES) stents in pulmonary vein stenosis (PVS). PVS is a serious condition with frequent restenosis after surgical and percutaneous interventions. After experiencing encouraging results with DES, we sought to compare outcomes

Clinical and mutational spectrum in a cohort of 105 unrelated patients with dilated cardiomyopathy.

Gilles Millat et al.

European journal of medical genetics, 54(6), e570-e575 (2011-08-19)

Dilated Cardiomyopathy (DCM) is one of the leading causes of heart failure with high morbidity and mortality. More than 30 genes have been reported to cause DCM. To provide new insights into the pathophysiology of dilated cardiomyopathy, a mutational screening

YKL-40 protein expression in the early developing human musculoskeletal system.

Julia S Johansen et al.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 55(12), 1213-1228 (2007-08-23)

YKL-40 is a growth factor for chondrocytes and fibroblasts. The aim was to evaluate YKL-40 expression in the musculoskeletal system during early human development. We studied sections from 15 human embryos [weeks 5.5-8; 7- to 31-mm crown-rump length (CRL)] and

Clonality, outer-membrane proteins profile and efflux pump in KPC- producing Enterobacter sp. in Brazil.

Juliana Ferraz Rosa et al.

BMC microbiology, 17(1), 69-69 (2017-03-18)

Carbapenems resistance in Enterobacter spp. has increased in the last decade, few studies, however, described the mechanisms of resistance in this bacterium. This study evaluated clonality and mechanisms of carbapenems resistance in clinical isolates of Enterobacter spp. identified in three

Alport syndrome: the effects of spironolactone on proteinuria and urinary TGF-β1.

Marisa Giani et al.

Pediatric nephrology (Berlin, Germany), 28(9), 1837-1842 (2013-06-12)

Alport syndrome (AS) is a progressive hereditary glomerular disease. Recent data indicate that aldosterone promotes fibrosis mediated by the transforming growth factor-β1 (TGF-β1) pathway, which may worsen proteinuria. Spironolactone (SP) antagonizes aldosterone and this study aimed to evaluate the efficacy

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