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D W Shaw
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 10(4), 228-232 (1999-12-14)
A patient with allergic contact dermatitis caused by benzyl alcohol in a hearing aid impression material and in topical medications is described. In addition, the patient had topical and probably systemic corticosteroid allergy. Benzyl alcohol allergy is reviewed. allergic contact
Stephen T Vito et al.
Toxicology and applied pharmacology, 281(2), 185-194 (2014-12-03)
Tetramethylenedisulfotetramine (TETS) is a potent convulsant poison for which there is currently no approved antidote. The convulsant action of TETS is thought to be mediated by inhibition of type A gamma-aminobutyric acid receptor (GABAAR) function. We, therefore, investigated the effects
Jun Zhou et al.
Journal of pharmaceutical and biomedical analysis, 94, 30-35 (2014-02-18)
A new and fast sample preparation technique based on two-phase hollow fiber liquid phase microextraction (HF-LPME) with magnetofluid was developed to quantitate and determine the four phenylethanoid glycosides (PhGs) (Echinacoside, Tubuloside B, Acteoside and Isoacteoside) in plasma after oral administration
L Gáspár et al.
Fogorvosi szemle, 91(5), 143-150 (1998-06-11)
The authors summarised the literature data of benzylalcohol and amyl-m-cresol. In the clinical practice they used Strepsils in the treatment of 22 patients suffered from oral inflammatic diseases and in the 20 prophylactic cases of oral surgical interventions. The preliminary
Shaoyin Wang et al.
Organic letters, 16(13), 3592-3595 (2014-06-25)
A novel Lewis acid catalyzed dehydrative [3 + 3]-annulation of readily available benzylic alcohols and propargylic alcohols was developed to give polysubstituted carbazoles and naphthalenes in moderate to good yields with water as the only byproduct. The reaction was presumed
Physostigmine Salicylate Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 30(6), 3535-3535 (2018)
Toralf Bork et al.
Biomedical microdevices, 16(5), 779-792 (2014-07-06)
The MedStream Programmable Infusion Pump, an intrathecal pump indicated for the treatment of chronic intractable pain and severe spasticity (CE-mark) or severe spasticity (US), has a highly accurate medication delivery (within 10% of the programmed flow rate) and is certified
Farhaan Hafeez et al.
Drug development and industrial pharmacy, 40(6), 838-844 (2013-04-23)
Onychomycosis is a common fungal infection of the nail plate and bed that affects up to 14% of the population and can have a substantial impact on the quality of life of those affected. This study compared the onychopharmacokinetics, nail
J Scognamiglio et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50 Suppl 2, S140-S160 (2011-11-01)
A toxicologic and dermatologic review of benzyl alcohol when used as a fragrance ingredient is presented. Benzyl alcohol is a member of the fragrance structural group Aryl Alkyl Alcohols and is a primary alcohol. The AAAs are a structurally diverse
Evgeni Eltzov et al.
Analytical chemistry, 87(7), 3655-3661 (2015-03-17)
Indoor air pollution became a recent concern found to be oftentimes worse than outdoor air quality. We developed a tool that is cheap and simple and enables continuous monitoring of air toxicity. It is a biosensor with both a nondisposable
B Nair
International journal of toxicology, 20 Suppl 3, 23-50 (2002-01-05)
Benzyl Alcohol is an aromatic alcohol used in a wide variety of cosmetic formulations as a fragrance component, preservative, solvent, and viscosity-decreasing agent. Benzoic Acid is an aromatic acid used in a wide variety of cosmetics as a pH adjuster
Endea J Curry et al.
Dermatitis : contact, atopic, occupational, drug, 16(4), 203-208 (2006-03-16)
Benzyl alcohol is a weak sensitizer found in a wide array of plants and plant products, foods, cosmetics, and medications. Delayed contact dermatitis reactions as well as immediate, urticarial, and systemic reactions have been reported to occur with its use
Subramanian Natesan et al.
Journal of drug targeting, 22(10), 913-926 (2014-08-15)
Development and evaluation of camptothecin-loaded-microemulsion (ME) and -magnetic microemulsion (MME) for passive/active-targeted delivery to BALB/c mice-bearing breast cancer. Based on the pseudo-ternary phase diagrams camptothecin-loaded-MEs and -MMEs were developed using benzyl alcohol:Captex 300 (3:1), TPGS:Tween 80 (2:1) and water. Furthermore
Megan K Luther et al.
The Journal of antimicrobial chemotherapy, 69(12), 3263-3267 (2014-08-07)
Antimicrobial lock solutions are used for prevention and management of catheter-related bloodstream infections. ML8-X10 (a prototype oil-in-water micro-emulsion based on a novel free fatty acid), vancomycin/heparin and taurolidine/citrate/heparin (Taurolock™-Hep500) lock solutions were tested against biofilm-forming Staphylococcus epidermidis and methicillin-susceptible Staphylococcus
Maria A Cavasin et al.
Journal of translational medicine, 12, 314-314 (2014-11-27)
Patients with pulmonary arterial hypertension (PAH) are treated with vasodilators, including endothelin receptor antagonists (ERAs), phosphodiesterase-5 (PDE-5) inhibitors, soluble guanylyl cyclase activators, and prostacyclin. Despite recent advances in pharmacotherapy for individuals with PAH, morbidity and mortality rates in this patient
Roy Bogseth et al.
Journal of the American Society for Mass Spectrometry, 25(11), 1987-1990 (2014-09-25)
Simple alcohols formed protonated acetonitrile adducts containing up to two acetonitrile molecules when analyzed by ESI or APCI in the presence of acetonitrile in the solvent. These acetonitrile adducts underwent dissociation to form a nitrilium ion, also referred to as
Y Zhu et al.
Neurobiology of disease, 74, 114-125 (2014-12-03)
Spinal cord injury (SCI) leads to formation of a fibrotic scar that is inhibitory to axon regeneration. Recent evidence indicates that the fibrotic scar is formed by perivascular fibroblasts, but the mechanism by which they are recruited to the injury
Aditya M Kunjapur et al.
Journal of the American Chemical Society, 136(33), 11644-11654 (2014-07-31)
Aromatic aldehydes are useful in numerous applications, especially as flavors, fragrances, and pharmaceutical precursors. However, microbial synthesis of aldehydes is hindered by rapid, endogenous, and redundant conversion of aldehydes to their corresponding alcohols. We report the construction of an Escherichia
Epidural administration of methylprednisolone acetate preserved with benzyl alcohol.
C C King et al.
The Annals of pharmacotherapy, 28(1), 59-60 (1994-01-01)
Jun Zhang et al.
Journal of pharmaceutical sciences, 104(5), 1592-1600 (2015-02-20)
Protein stability, one of the major concerns for therapeutic protein development, can be optimized during process development by evaluating multiple formulation conditions. This can be a costly and lengthy procedure where different excipients and storage conditions are tested for their
Laura A Jones et al.
The Journal of cell biology, 207(4), 499-516 (2014-11-26)
Cytoplasmic dynein 1 (dynein) is a minus end-directed microtubule motor protein with many cellular functions, including during cell division. The role of the light intermediate chains (LICs; DYNC1LI1 and 2) within the complex is poorly understood. In this paper, we
Thomas Pöschinger et al.
Investigative radiology, 49(7), 445-456 (2014-03-07)
Dynamic contrast-enhanced (DCE) micro-computed tomography (micro-CT) has emerged as a valuable imaging tool to noninvasively obtain quantitative physiological biomarkers of drug effect in preclinical studies of antiangiogenic compounds. In this study, we explored the ability of DCE micro-CT to assess
Nikki M Magdaong et al.
The journal of physical chemistry. B, 118(38), 11172-11189 (2014-08-30)
Rhodopin, rhodopinal, and their glucoside derivatives are carotenoids that accumulate in different amounts in the photosynthetic bacterium, Rhodoblastus (Rbl.) acidophilus strain 7050, depending on the intensity of the light under which the organism is grown. The different growth conditions also
Kyra J Barnes et al.
European journal of clinical pharmacology, 70(9), 1097-1106 (2014-06-24)
To investigate the potential inhibitory effects of uremic toxins on the major human hepatic drug-metabolising cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT) enzymes in vitro. Benzyl alcohol, p-cresol, indoxyl sulfate, hippuric acid and a combination of the four uremic toxins were
Luca Nicolotti et al.
Journal of chromatography. A, 1360, 264-274 (2014-08-19)
Comprehensive two-dimensional gas chromatography (GC×GC) coupled with Mass Spectrometry (MS) is one of today's most powerful analytical platforms for detailed analysis of medium-to-high complexity samples. The column set usually consists of a long, conventional-inner-diameter first dimension ((1)D) (typically 15-30m long
Anthony J Donato et al.
Life sciences, 118(2), 238-243 (2014-01-15)
The role of vascular smooth muscle endothelin A receptors (ETA) in development and normal physiology remains incompletely understood. To address this, mice were generated with smooth muscle-specific knockout (KO) of ETA. Mice were homozygous for loxP-flanked exons 6-8 of the
?341? Antimicrobial agents content
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(2), 6664-6664 (2016)
Enalaprilat Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 34(3), 1619-1619 (2022)
Mussel-inspired bolaamphiphile sticky self-assemblies for the preparation of magnetic nanoparticles.
Chaemyeong Lee et al.
Colloids and surfaces. B, Biointerfaces, 127, 89-95 (2015-02-07)
Adopting the strong metal binding moiety of a mussel protein, a novel bolaamphiphile molecule was prepared and applied to the fabrication of magnetic core-shell nanoparticles. The novel bolaamphiphile molecule with 3,4-dihydroxyphenylalanine (DOPA) end groups was synthesized and its self-assembly was
Vanessa Alves Pinheiro et al.
Pharmaceutical development and technology, 20(2), 197-203 (2013-11-30)
With the aim of reducing system absorption and consequently, the side effects, and simultaneously select a penetration enhancing, three topical formulations with 0.5% ciclopirox olamine (CO) and 15% of propylene glycol (PG), ethoxydiglycol or oleic acid were developed and evaluated
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