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显示 1-21 共 21 条结果 关于 "107-35-7" 范围 论文
Giovanni Cazzaniga et al.
Blood, 106(4), 1419-1422 (2005-05-05)
Nucleophosmin (NPM) is a nucleocytoplasmic shuttling protein involved in leukemia-associated chromosomal translocations, and it regulates the alternate reading frame (ARF)-p53 tumor-suppressor pathway. Recently, it has been demonstrated that mutations of the NPM1 gene alter the protein at its C-terminal, causing
Dong Mi et al.
Journal of cancer research and clinical oncology, 137(2), 295-303 (2010-04-20)
PTHrP, a mediator of humoral hypercalcemia of malignancy, is considered as a potential activator to induce breast cancer cells metastasizing to bone. However, recent clinical evidences and basal research results prove that PTHrP expression in primary tumors indicates good prognosis.
Sa Xiao et al.
Virus research, 145(1), 80-91 (2009-06-23)
The complete genome sequence of avian paramyxovirus serotype 7 (APMV-7) prototype strain dove/Tennessee/4/75 was determined. The genome size is 15,480 nucleotides (nt) long and follows the "rule of six". The genome contains six non-overlapping genes in the order of 3'-N-P/V/W-M-F-HN-L-5'.
Benjamin Speich et al.
The Lancet. Infectious diseases, 15(3), 277-284 (2015-01-16)
Existing anthelmintic drugs (eg, albendazole and mebendazole) have low efficacy against the intestinal nematode species Trichuris trichiura and the drug pipeline is exhausted. We aimed to investigate the strategy of combination chemotherapy with existing drugs to establish whether their efficacy
N L Anderson et al.
Toxicology and applied pharmacology, 137(1), 75-89 (1996-03-01)
We have investigated the effects of five peroxisome proliferators (PPs : clofibric acid, DEHP, WY14,643, nafenopin, and LY171883) on the abundances of a large number of proteins in the livers of treated mice at 5- and 35-day time points. LY171883
Abinash Virk et al.
Journal of travel medicine, 20(2), 88-94 (2013-03-08)
Travelers' diarrhea (TD) is a significant problem for travelers. TD is treatable once it occurs, but few options for prevention exist. Probiotics have been studied for prevention or treatment of TD; however, very few combination probiotics have been studied. Therefore
Ji Shi et al.
Zhonghua zhong liu za zhi [Chinese journal of oncology], 32(10), 748-751 (2010-12-18)
China has the highest incidence and mortality of esophageal carcinoma in the world, and the esophageal squamous cell carcinoma (ESCC) is the major type. In this study, the authors investigated the expression of Aurora-A in stage T3 esophageal squamous cell
Valérie Le Morvan et al.
Pharmacogenomics, 8(12), 1693-1703 (2007-12-19)
Glutathione S-transferase P1 (GSTP1) and excision-repair cross-complementing repair deficiency group 2 protein (ERCC2 or XPD) may modulate the activity of platinum derivatives. The SNPs, Ile105Val for GSTP1 and Lys751Gln for ERCC2, may affect the efficiency of oxaliplatin in patients treated
Yingzi Lin et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 26(10), 839-845 (2003-11-19)
We have previously reported that urotensin II acts on the central nervous system to increase blood pressure in normotensive rats. In the present study, we have determined the central cardiovascular action of urotensin II in spontaneously hypertensive rats (SHR). Intracerebroventricular
Olli Tenhunen et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 20(11), 1907-1909 (2006-07-20)
As a leading cause of heart failure, postinfarction left ventricular remodeling represents an important target for therapeutic interventions. Mitogen-activated protein kinases regulate critical cellular processes including stress response and survival, but their role in left ventricular remodeling is unknown. In
Jürgen Knapp et al.
Shock (Augusta, Ga.), 43(6), 576-581 (2015-02-24)
The immunosuppressant drug cyclosporine A (CsA) is a direct inhibitor of the mitochondrial permeability transition pore, which is the common end point of many pathways of ischemic preconditioning and postconditioning. We studied the neuroprotective and cardioprotective effect of CsA after
Genevieve C Luca et al.
Veterinary anaesthesia and analgesia, 47(3), 334-340 (2020-03-31)
To describe the pharmacokinetics of ketamine following a short intravenous (IV) infusion to isoflurane-anesthetized rabbits. Prospective experimental study. A total of six adult healthy female New Zealand White rabbits. Anesthesia was induced with isoflurane in oxygen. Following determination of isoflurane
P Sabbatini et al.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 17(3), 589-594 (2007-02-16)
The objective of this study was to analyze retrospective populations with recurrent ovarian cancer to assess differences in CA-125 patterns during chemotherapy. The populations included all patients treated between January 1994 and January 2004, who received liposomal doxorubicin and topotecan
S Barnes et al.
Journal of lipid research, 30(4), 529-540 (1989-04-01)
A bile acid:3'phosphoadenosine-5'phosphosulfate:sulfotransferase (BAST I) from adult female rat liver cytosol has been purified 157-fold by a two-step isolation procedure. The N-terminal amino acid sequence of the 30,000 subunit has been determined for the first 35 residues. The Vmax of
Antonios N Pouliopoulos et al.
Frontiers in physics, 8 (2020-05-28)
Non-invasive blood-brain barrier (BBB) opening using focused ultrasound (FUS) is being tested as a means to locally deliver drugs into the brain. Such FUS therapies require injection of preformed microbubbles, currently used as contrast agents in ultrasound imaging. Although their
Claire L Green et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 28(16), 2739-2747 (2010-05-05)
To determine the clinical relevance of mutations in the CCAAT/enhancer binding protein alpha (CEBPA) gene in acute myeloid leukemia (AML) and to examine factors that might modify prognostic impact. The entire CEBPA coding sequence was screened in 1,427 young adult
F Beugnet et al.
Parasite (Paris, France), 18(4), 325-331 (2011-11-18)
In the study reported here, the pioneer fipronil/(S)-methoprene topical product (Frontline® Plus, Merial Limited, Duluth, GA) was compared to the oral spinosad product (Comfortis® Elanco, Greenfield, IN) for efficacy against adult fleas and preventing egg production. The product presentations, doses
James Cronin et al.
The American journal of gastroenterology, 106(1), 46-56 (2010-12-16)
The assessment of cancer risk in patients with Barrett's esophagus (BE) is currently fraught with difficulty. The current gold standard method of assessing cancer risk is histological assessment, with the appearance of high-grade dysplasia (HGD) as the key event monitored.
Benedikt Ringbeck et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1141, 122029-122029 (2020-02-29)
Di-n-butyl adipate (DnBA) is an alternative to the anti-androgenic and strictly regulated di-n-butyl phthalate (DnBP) used as a cosmetic ingredient, plasticizer, and in various articles of everyday life. Hence, exposures of the general population have to be expected. Currently, biomarkers
Rami Kantor et al.
Journal of the International AIDS Society, 17, 19262-19262 (2014-11-22)
Antiretroviral resistance leads to treatment failure and resistance transmission. Resistance data in western Kenya are limited. Collection of non-plasma analytes may provide additional resistance information. We assessed HIV diversity using the REGA tool, transmitted resistance by the WHO mutation list
Jelena S Rudic et al.
The Cochrane database of systematic reviews, 12, CD000551-CD000551 (2012-12-14)
Ursodeoxycholic acid is administered to patients with primary biliary cirrhosis, a chronic progressive inflammatory autoimmune-mediated liver disease with unknown aetiology. Despite its controversial effects, the U.S. Food and Drug Administration has approved its usage for primary biliary cirrhosis. To assess
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