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关键词:'107 623-21-2'
显示 1-30 共 70 条结果 关于 "107 623-21-2" 范围 论文
Takako Yanai et al.
Anticancer research, 32(12), 5521-5526 (2012-12-12)
Discontinuation of oxaliplatin-containing regimens is sometimes necessary due to hypersensitivity reactions for which effective countermeasures have not yet been identified. We retrospectively reviewed cases in which hypersensitivity reactions developed in 623 patients treated with oxaliplatin for colorectal cancer. Clinical outcomes
Satoshi Fukuda et al.
Scientific reports, 11(1), 23966-23966 (2021-12-16)
In sepsis, microvascular hyperpermeability caused by oxidative/nitrosative stress (O&NS) plays an important role in tissue edema leading to multi-organ dysfunctions and increased mortality. We hypothesized that a novel compound R-107, a modulator of O&NS, effectively ameliorates the severity of microvascular
Daniela Sia et al.
Nature communications, 6, 6087-6087 (2015-01-23)
Intrahepatic cholangiocarcinoma (iCCA) is a fatal bile duct cancer with dismal prognosis and limited therapeutic options. By performing RNA- and exome-sequencing analyses, we report a novel fusion event, FGFR2-PPHLN1 (16%), and damaging mutations in the ARAF oncogene (11%). Here we
J H Fingert et al.
Human molecular genetics, 8(5), 899-905 (1999-04-10)
A glaucoma locus, GLC1A, was identified previously on chromosome 1q. A gene within this locus (encoding the protein myocilin) subsequently was shown to harbor mutations in 2-4% of primary open angle glaucoma patients. A total of 1703 patients was screened
Xiao-wen Yin et al.
Zhonghua yi xue za zhi, 90(26), 1808-1812 (2010-10-29)
To evaluate the influence of mutations in epidermal growth factor receptor (EGFR) gene on the prognosis of non-small cell lung cancer (NSCLC). A total of 107 NSCLC patients undergoing tumor resection from December 2005 to August 2009 at our hospital
Shingo Matsumoto et al.
International journal of cancer, 118(10), 2498-2504 (2005-12-15)
Mutations of the epidermal growth factor receptor gene (EGFR) have been reported to be present in a considerable fraction of lung adenocarcinomas showing dramatic response to EGFR tyrosine kinase inhibitors. To clarify pathogenic significance of the mutations for the development
Larisa Kovacevic et al.
Journal of pediatric urology, 11(4), 217-217 (2015-06-17)
The gene mutations responsible for cystinuria do not fully explain kidney stone activity, suggesting that specific proteins may serve as promoters of cystine precipitation, aggregation or epithelial adherence. In this study we assessed (1) the differences in the urinary proteins
Yuanyuan Wu et al.
Poultry science, 98(1), 150-163 (2018-08-24)
This study evaluated the effects of dietary Enterococcus faecium NCIMB 11181 on growth performance and immune response in broiler chickens. A total of 360 1-day-old Arbor Acres male birds were randomly assigned to 4 treatments that administered different dosages of
Hidefumi Kita et al.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 17(5), 454-460 (2011-09-02)
We examined the influence of inflammatory cytokine levels on postoperative early recurrence in patients who underwent curative lung cancer surgery. In 107 patients who underwent curative pulmonary resections for non-small cell lung cancer (NSCLC) from November 2007 to June 2008
F Loisel et al.
Journal of animal science, 92(7), 2931-2941 (2014-05-08)
It was hypothesized that colostrum production could be influenced by sow peripartum endocrine, metabolic, and hepatic status. The plant extract silymarin was shown to influence endocrine and hepatic status in several species. The aims of the present study were to
Frank J Schenck et al.
Journal of AOAC International, 89(1), 196-200 (2006-03-04)
A reversed-phase liquid chromatographic (LC) method is presented for the analysis of N-methyl carbamate pesticide residues and piperonyl butoxide in eggs at levels as low as 2 microg/kg (ppb). The study was undertaken to provide data for dietary exposure estimates
Toshihiko Mayumi et al.
Pancreas, 41(6), 869-875 (2012-04-07)
A simple urinary trypsinogen-2 test was evaluated for the diagnosis of acute pancreatitis. This prospective multicenter study enrolled consecutive patients with acute abdominal pain who presented to the emergency department or who were hospitalized at 1 of 21 medical institutions
Feng Chen et al.
International journal of clinical and experimental medicine, 8(6), 9820-9824 (2015-08-27)
Tumour markers are used extensively for the management of lung cancer, including diagnosis, evaluating effectiveness of treatments, monitoring recurrence after therapy and for predicting prognosis. However, there exists a knowledge gap regarding potential quantitative correlations between tumour marker levels and
Arezue F B Boroujerdi et al.
Analytical and bioanalytical chemistry, 404(3), 777-784 (2012-07-10)
Nuclear magnetic resonance (NMR) spectroscopy has been used to obtain metabolic profiles of the polar diatom Fragilariopsis cylindrus, leading to the identification of a novel metabolite in this organism. Initial results from an ongoing metabolomics study have led to the
Jennifer L H Johnson et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 117(3), 246-250 (2016-09-11)
Three albuterol sulfate metered-dose inhaled (MDI) products (Ventolin HFA, Proventil HFA, and ProAir HFA) are marketed in the United States to provide the same total dose of albuterol sulfate. However, it is widely known that the fine particle dose (<5
G Wu et al.
The Journal of nutrition, 127(12), 2342-2349 (1998-01-24)
This study was conducted to determine whether endogenous synthesis of arginine plays a role in regulating arginine homeostasis in postweaning pigs. Pigs were fed a sorghum-based diet containing 0. 98% arginine and were used for studies at 75 d of
Zhao-Hui Yin et al.
World journal of gastroenterology, 11(8), 1232-1236 (2005-03-09)
To investigate the expression of tumor necrosis factor-alpha (TNF-alpha) and vascular endothelial growth factor (VEGF) in the development of esophageal varices in portal hypertensive rats. Thirty male Sprague-Dawley (SD) rats in the model group in which a two-stage ligation of
Young Woon Park et al.
The Journal of dermatological treatment, 25(5), 391-395 (2013-01-01)
Propranolol has recently become a successful first-line therapy in the treatment of infantile hemangiomas (IHs). To evaluate and analyze the authors' experience of propranolol treatment for IHs. A retrospective, observational study was conducted. Medical records were reviewed. To evaluate the
M Z Haider et al.
Biology of the neonate, 82(2), 84-88 (2002-08-10)
Retinopathy of prematurity (ROP) is a disease characterized by neovascularization which occurs in infants with short gestational age and low birth weight and can lead to retinal detachment and blindness. In a proportion of ROP cases, the disease progresses to
G R Garcia et al.
Beneficial microbes, 10(1), 33-42 (2018-10-03)
Probiotics represents an alternative to replace antibiotics as growth promoters in animal feed and are able to control enteric bacterial diseases and to improve gut immunity. Saccharomyces cerevisiae RC016 showed previously inhibition/coagregation of pathogens) and mycotoxins adsorbent ability (aflatoxin B1
Urh Groselj et al.
Molecular genetics and metabolism, 106(2), 142-148 (2012-04-20)
Mutational spectrum of the phenylalanine hydroxylase (PAH) deficiency was investigated in 107 families (90% of the Slovene PKU population). The entire coding region of the PAH gene was analyzed with dHPLC to select the samples where subsequently the automated sequencing
Adrian Wiestner et al.
Blood, 101(12), 4944-4951 (2003-02-22)
The presence or absence of somatic mutations in the expressed immunoglobulin heavy chain variable regions (IgVH) of chronic lymphocytic leukemia (CLL) cells provides prognostic information. Patients whose leukemic cells express unmutated IgVH regions (Ig-unmutated CLL) often have progressive disease, whereas
P Sabbatini et al.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 17(3), 589-594 (2007-02-16)
The objective of this study was to analyze retrospective populations with recurrent ovarian cancer to assess differences in CA-125 patterns during chemotherapy. The populations included all patients treated between January 1994 and January 2004, who received liposomal doxorubicin and topotecan
F Azizi et al.
Journal of endocrinological investigation, 26(8), 703-709 (2003-12-13)
Changes in serum lipid and lipoprotein concentrations occur frequently in disorders of thyroid function. LDL-cholesterol (LDL-C) oxidation susceptibility is higher in these patients than in normal population. This study aims at assessing lipids, lipoproteins, apolipoproteins and serum paraoxonase 1 (PON1)
Robert L Hanson et al.
Molecular genetics and metabolism, 101(4), 383-390 (2010-09-10)
Variants in the engulfment and cell motility 1 gene, ELMO1, have previously been associated with kidney disease attributed to type 2 diabetes. The Pima Indians of Arizona have high rates of diabetic nephropathy, which is strongly dependent on genetic determinants;
Tai-song Zhang et al.
Chinese medical journal, 119(4), 294-299 (2006-03-16)
There were some papers published in the Jonrnal of Science, December 2000 suggesting that one or more important susceptibility genes for late onset Alzheimer's disease (LOAD) were located on the long arm of chromosome 10. Linkage analysis showed maximum lod
F J Couch et al.
Human mutation, 8(1), 8-18 (1996-01-01)
Mutations in the familial early-onset breast cancer gene (BRCA1) account for approximately 2-5% of all breast cancer cases (Easton et al., 1993). Since the isolation of the BRCA1 gene in 1994, many mutations have been identified. We report here a
Meng-hong Sun et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 40(10), 655-659 (2012-02-11)
To retrospectively analyze epidermal growth factor receptor (EGFR) gene mutation frequencies and distribution characteristics in Chinese patients with non-small-cell lung carcinoma (NSCLC) by direct gene sequencing. Clinical samples from 443 NSCLC patients were obtained for EGFR gene mutation analysis, including
Kyle K Biggar et al.
Gene, 544(1), 67-74 (2014-04-29)
Recent research has highlighted roles for non-coding RNA i7n the regulation of stress tolerance in bats. In this study, we propose that microRNA could also play an important role in neuronal maintenance during hibernation. To explore this possibility, RT-PCR was
Michael S Korenfeld et al.
Journal of cataract and refractive surgery, 35(1), 26-34 (2008-12-23)
To assess the efficacy and safety of difluprednate ophthalmic emulsion 0.05% (Durezol) 2 or 4 times a day compared with those of a placebo in the treatment of inflammation and pain associated with ocular surgery. Twenty-six clinics in the United
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