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Shawn Vasoo et al.
Antimicrobial agents and chemotherapy, 59(12), 7842-7846 (2015-09-24)
Among 177 carbapenemase-producing Gram-negative bacilli (108 KPC, 32 NDM, 11 IMP, 8 OXA-48, 4 OXA-181, 2 OXA-232, 5 IMI, 4 VIM, and 3 SME producers), aztreonam-avibactam was active against all isolates except two NDM producers with elevated MICs of 8/4
Dennis R Johnson et al.
World journal of gastroenterology, 21(9), 2770-2776 (2015-03-12)
To compare the sensitivity and specificity of CDX2 and alcian blue (AB) pH 2.5 staining in identifying esophageal intestinal metaplasia. One hundred and ninty-nine biopsies from 186 patients were retrospectively reviewed and categorized as Barrett's esophagus (BE) (n = 108);
R C Hapak et al.
The Journal of biological chemistry, 269(7), 5288-5296 (1994-02-18)
CPV3 is a novel avian parvalbumin. It displays an isoelectric point of 4.6, intermediate between that of avian thymic hormone (pI = 4.3) and the muscle parvalbumin isoform (pI = 5.2). Expression of CPV3, like that of avian thymic hormone
Yinan Wang et al.
Immunogenetics, 70(5), 337-346 (2017-10-28)
In this study, a homolog of the TLR11 family gene from the sea urchin Strongylocentrotus intermedius (denoted as SiTLR11) was cloned and characterized. The full-length cDNA of SiTLR11 was 2096-bp long, which included 43 bp of 5' untranslated region (UTR), 238 bp
Sumanta Kumar Mallik et al.
Antonie van Leeuwenhoek, 113(12), 2063-2076 (2020-10-31)
In the study, Aeromonas strains (n = 12) were isolated from moribund grass carp fry reared in the cage culture unit from the Central Himalayan region of India. They were identified as Aeromonas veronii, by biochemically and 16S rRNA analysis. The experimental
Yu-Feng Zhou et al.
Frontiers in microbiology, 10, 2957-2957 (2020-01-24)
Infections due to carbapenem-resistant NDM-producing Escherichia coli represent a major therapeutic challenge, especially in situations of pre-existing colistin resistance. The aim of this study was to investigate combinatorial pharmacodynamics of colistin and tigecycline against E. coli harboring blaNDM-5 and mcr-1
Kenneth F Egbadzor et al.
SpringerPlus, 3, 541-541 (2014-10-22)
Single Nucleotide Polymorphism (SNP) markers were used in characterization of 113 cowpea accessions comprising of 108 from Ghana and 5 from abroad. Leaf tissues from plants cultivated at the University of Ghana were genotyped at KBioscience in the United Kingdom.
Massimo Allegri et al.
Journal of pain research, 10, 2515-2524 (2017-12-01)
Continuous wound infusion (CWI) may protect from inflammation, hyperalgesia and persistent pain. Current local anesthetics display suboptimal pharmacokinetic profile during CWI; chloroprocaine (CP) has ideal characteristics, but has never been tested for CWI. We performed an animal study to investigate
Carsten Boltze et al.
Oncology reports, 10(6), 1783-1787 (2003-10-10)
The serine protease inhibitor maspin has been reported to inhibit invasiveness and motility of tumor cells. Additionally, a p53-dependent regulatory pathway of maspin in human cancer has been indicated. In a pre-study we were able to detect maspin protein in
Upregulation of endogenous ICAM-1 reduces ovarian cancer cell growth in the absence of immune cells.
Marloes L de Groote et al.
International journal of cancer, 134(2), 280-290 (2013-07-09)
Ovarian cancer is a difficult-to-treat cancer with a 5-year survival rate of only ∼45%, due to late diagnosis and therapy resistance. In need of new therapeutic approaches, induction of intercellular adhesion molecule (ICAM)-1 expression might be of interest, since the
G Woldegiorgis et al.
Analytical biochemistry, 150(1), 8-12 (1985-10-01)
Long-chain acyl-CoA esters were extracted from freeze-clamped livers of fed and fasted rats according to the method of Mancha et al. [M. Mancha, G. B. Stokes, and P. K. Stumpf (1975) Anal. Biochem. 68, 600-608] and analyzed on a radially
Shigeo Ikeda et al.
Annals of surgery, 237(5), 677-685 (2003-05-02)
To determine the influence of route of nutrition on gut mucosal addressin cellular adhesion molecule-1 (MAdCAM-1) expression and the effect of MAdCAM-1 blockade on gut-associated lymphoid tissue (GALT) lymphocyte populations and established respiratory antibacterial immunity. Lymphocytes, sensitized to antigens in
Yu-mei Liu et al.
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 47(12), 1089-1095 (2012-02-18)
To investigate the role of endothelial progenitor cells (EPC) in the injury of rat optic nerve. An experimental study. The rat model of optic nerve injury was created by fluid percussion brain injury device (FPI). On hundred and eight rats
K E Hill et al.
New Zealand veterinary journal, 62(4), 208-213 (2013-12-20)
To determine the pharmacokinetics of a novel lipophilic formulation of transdermal methimazole compared to oral carbimazole. Healthy cats received 5 mg carbimazole orally every 12 hours for 13 treatments (n=6), then received transdermal methimazole (n=5) at a dose of 5 mg, then
J Rosén
The Analyst, 126(11), 1990-1995 (2002-01-05)
A method using liquid chromatography tandem mass spectrometry (LC-MS-MS) with electrospray (ES) for the determination of traces of narasin, monensin and salinomycin in chicken liver and eggs was developed, validated and used for routine surveillance. The essence of this paper
Yang Xiang et al.
Acta biochimica et biophysica Sinica, 37(1), 11-18 (2005-01-13)
Cystatins are cysteine proteinase inhibitors. We found two expression sequence tags (ESTs), CA463109 and AV042522, from a mouse testis library using Digital differential display (DDD). By electrical hybridization, a novel gene, Cymg1 (GenBank accession No. AY600990), which has a full
Vivian Cody et al.
Acta crystallographica. Section D, Biological crystallography, 59(Pt 4), 654-661 (2003-03-27)
The results of the crystal structure determination of human dihydrofolate reductase (hDHFR) as a binary complex with the potent N9-C10 reversed-bridge antifolate inhibitor 2,4-diamino-6-[N-(3',4',5'-trimethoxybenzyl)-N-methylamino]pyrido[2,3-d]pyrimidine (1) are reported for two independent polymorphic rhombohedral R3 lattices [R3(1) and R3(2)]. Data from these
Gianni Sagratini et al.
Journal of chromatography. A, 1194(2), 213-220 (2008-05-20)
A new analytical method, using gas chromatography-mass spectrometry (GC/MS) and liquid chromatography-mass spectrometry (LC/MS) techniques, was developed for the determination in packaged food beverages of five ink photoinitiator residues: 2-isopropylthioxanthone (ITX), benzophenone, 2-ethylhexyl-4-dimethylaminobenzoate (EHDAB), 1-hydroxycyclohexyl-1-phenyl ketone (IRGACURE 184) and ethyl-4-dimethylaminobenzoate
Rile Li et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 10(12 Pt 1), 4118-4124 (2004-06-26)
Proliferative activity defined by Ki-67 staining index (SI) has been correlated with progression and prognosis in a number of malignant tumors including prostate cancer. However, few studies have examined Ki-67 SI in pretreatment diagnostic material from patients treated with definitive
S A Adedokun et al.
Poultry science, 93(4), 935-942 (2014-04-08)
The objective of the current study was to determine the effect of nitrogen-free diets formulated with 2 ratios of corn starch and dextrose and 2 levels of dietary electrolyte balance (DEB; calculated as Na + K - Cl(-), in mEq/kg
M M Porter-Turner et al.
British journal of biomedical science, 68(4), 203-207 (2012-01-24)
This paper investigates the effect of glycation on glucose transport in erythrocytes. Glucose transporter function, numbers and erythrocyte phosphorylation rates are simultaneously studied using 30 Caucasian patients with diabetes and 30 Caucasian control volunteers (mean +/- SD where P <
Na Ren et al.
Molecular medicine reports, 12(5), 6561-6567 (2015-09-02)
Tuberculosis (TB) infections, caused by multidrug‑resistant Mycobacterium tuberculosis (MDR MTB), remain a significant public health concern worldwide. The regulatory mechanisms underlying the emergence of MDR MTB strains remain to be fully elucidated, and further investigation is required in order to
Michael Stenger et al.
PloS one, 10(8), e0135571-e0135571 (2015-08-13)
The rise in antimicrobial resistance is a major global concern and requires new treatment strategies. The use of helper compounds, such as thioridazine (TDZ), an antipsychotic drug, in combination with traditional antibiotics must be investigated. The aim of this study
Elena Valassi et al.
Clinical endocrinology, 77(5), 735-742 (2012-04-27)
To evaluate the outcome of preoperative therapy with ketoconazole (KTZ) and/or metyrapone (MTP) in previously untreated patients with Cushing's syndrome (CS). Sixty-two patients with CS (85% ACTH dependent), treated with steroidogenesis inhibitors prior to surgery between 1983 and 2010, were
Sarah L Baldridge et al.
American journal of veterinary research, 72(10), 1305-1317 (2011-10-04)
To determine the pharmacokinetic parameters of xylazine, ketamine, and butorphanol (XKB) administered IM and sodium salicylate (SAL) administered PO to calves and to compare drug effects on biomarkers of pain and distress following sham and actual castration and dehorning. 40
S K Kabra et al.
Indian pediatrics, 40(7), 612-619 (2003-07-26)
To document clinical profile of cystic fibrosis (CF) in Indian children and the prevalence of delta F508 mutation in these patients. Observational study. Pediatric chest clinic in an urban tertiary care center in north India. July 1995 to June 2002.
Donald J McMahon et al.
Journal of dairy science, 103(10), 8771-8781 (2020-08-05)
Understanding characteristics that permit survival and growth of Paucilactobacillus wasatchensis as part of the nonstarter microbiota of cheese is important for minimizing unwanted gas formation in cheese that can cause downgrading because of slits and cracks. The ability of Plb.
Nicola Sweeney et al.
PloS one, 16(4), e0249791-e0249791 (2021-04-08)
During the first wave of the global COVID-19 pandemic the clinical utility and indications for SARS-CoV-2 serological testing were not clearly defined. The urgency to deploy serological assays required rapid evaluation of their performance characteristics. We undertook an internal validation
Se Joon Woo et al.
JAMA ophthalmology, 139(1), 68-76 (2020-11-20)
Neovascular age-related macular degeneration is the leading cause of blindness in individuals 50 years or older. The availability of a ranibizumab biosimilar product (SB11) may facilitate access to an effective alternative to this treatment. To demonstrate equivalence of efficacy, similar
P J Reis et al.
Journal of animal science, 77(5), 1224-1229 (1999-05-26)
The effects of intravenous infusion of mimosine or 2,3-dihydroxypyridine (2,3-DHP) and the effects of oral dose level of mimosine on fiber shedding in Angora goats were determined. In one experiment, 20 mature Angora wethers (36+/-1.9 kg BW) were infused for
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