108-74-7

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Mutational spectrum of F8 gene and prothrombotic gene variants in haemophilia A patients from Southern Italy.

V Sanna et al.

Haemophilia : the official journal of the World Federation of Hemophilia, 14(4), 796-803 (2008-05-08)

Haemophilia A (HA) is an X-linked recessive haemorrhagic disorder caused by a deficiency of coagulation factor VIII. Disease causative mutations are heterogeneous and spread all over the F8 gene sequence, with the exception of intron 22 inversion occurring in about

Association of double-positive FOXA1 and FOXP1 immunoreactivities with favorable prognosis of tamoxifen-treated breast cancer patients.

Nobuhiro Ijichi et al.

Hormones & cancer, 3(4), 147-159 (2012-04-06)

Breast cancer is primarily a hormone-dependent tumor that can be regulated by the status of the steroid hormones estrogen and progesterone. Forkhead box A1 (FOXA1) is a member of the forkhead box transcription factor family and functions as a pioneer

FDG uptake observed around the lumbar spinous process: relevance to Baastrup disease.

Kayo Nishimatsu et al.

Annals of nuclear medicine, 29(9), 766-771 (2015-07-15)

In positron emission tomography (PET) with F-18-fluorodeoxyglucose (FDG), non-tumorous focal uptake is often observed around the lumbar spinous processes (LSPs). Close approximation of LSPs with sclerosis is often seen, which is called Baastrup disease. The aim of this study was

Relationship between erythrocyte GLUT1 function and membrane glycation in type 2 diabetes.

M M Porter-Turner et al.

British journal of biomedical science, 68(4), 203-207 (2012-01-24)

This paper investigates the effect of glycation on glucose transport in erythrocytes. Glucose transporter function, numbers and erythrocyte phosphorylation rates are simultaneously studied using 30 Caucasian patients with diabetes and 30 Caucasian control volunteers (mean +/- SD where P <

Low-affinity signature of the rat beta-parvalbumin CD site. Evidence for remote determinants.

Michael T Henzl et al.

Biochemistry, 46(1), 23-35 (2007-01-03)

Although rat beta-parvalbumin and chicken parvalbumin 3 (CPV3) are identical at 74 of 108 residues, rat beta exhibits perceptibly lower Ca2+ and Mg2+ affinities. At 25 degrees C, in Hepes-buffered saline, at pH 7.4, the overall deltadeltaG degrees ' values

Amino acid solutions for premature neonates during the first week of life: the role of N-acetyl-L-cysteine and N-acetyl-L-tyrosine.

J B Van Goudoever et al.

JPEN. Journal of parenteral and enteral nutrition, 18(5), 404-408 (1994-09-01)

Tyrosine and cyst(e)ine are amino acids that are thought to be essential for preterm neonates. These amino acids have low stability (cyst(e)ine) or low solubility (tyrosine) and are therefore usually present only in small amounts in amino acid solutions. Acetylation

Low-Volume Lymph Node Metastases in Endometrial Carcinoma.

Lani K Clinton et al.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 27(6), 1165-1170 (2017-06-13)

The aim of this study was to determine the histopathologic characteristics of patients with endometrial carcinoma with low-volume metastases (micrometastases and isolated tumor cells) compared with macrometastases. We performed a retrospective review of patients with endometrial carcinoma. Among 350 robotic-assisted

Plaque Morphology as Predictor of Late Plaque Events in Patients With Asymptomatic Type 2 Diabetes: A Long-Term Observational Study.

David A Halon et al.

JACC. Cardiovascular imaging, 12(7 Pt 2), 1353-1363 (2018-05-21)

The authors used coronary computed tomography angiography (CTA) to determine plaque characteristics predicting individual late plaque events precipitating acute coronary syndromes (ACS) in a cohort of asymptomatic type 2 diabetic patients. In patients with coronary artery disease, CTA plaque characteristics may predict mid-term

Efficacy and safety of albendazole plus ivermectin, albendazole plus mebendazole, albendazole plus oxantel pamoate, and mebendazole alone against Trichuris trichiura and concomitant soil-transmitted helminth infections: a four-arm, randomised controlled trial.

Benjamin Speich et al.

The Lancet. Infectious diseases, 15(3), 277-284 (2015-01-16)

Existing anthelmintic drugs (eg, albendazole and mebendazole) have low efficacy against the intestinal nematode species Trichuris trichiura and the drug pipeline is exhausted. We aimed to investigate the strategy of combination chemotherapy with existing drugs to establish whether their efficacy

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