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Marina Boussiou et al.
Blood cells, molecules & diseases, 40(3), 317-319 (2007-12-22)
Beta-thalassemia is the most predominant genetic defect in Greece. In this study, we investigated the heterogeneity and the frequency of beta-thalassemia mutations among 3796 heterozygotes detected in the course of DNA based diagnoses. The diagnostic strategy included Denaturing Gradient Gel
Elena Valassi et al.
Clinical endocrinology, 77(5), 735-742 (2012-04-27)
To evaluate the outcome of preoperative therapy with ketoconazole (KTZ) and/or metyrapone (MTP) in previously untreated patients with Cushing's syndrome (CS). Sixty-two patients with CS (85% ACTH dependent), treated with steroidogenesis inhibitors prior to surgery between 1983 and 2010, were
Nienke Molenaar et al.
Clinical biochemistry, 48(16-17), 1053-1058 (2015-07-15)
To investigate the agreement between the calculated free cortisol levels according to widely applied Coolens and adjusted Södergård equations with measured levels in the critically ill. A prospective study in a mixed intensive care unit. We consecutively included 103 patients
Yujiro Nozawa et al.
Human pathology, 43(6), 878-887 (2011-11-15)
Alpha-methylacyl-coenzyme A racemase controls β-oxidation of branched-chain fatty acid and their derivatives. Many investigators have described alpha-methylacyl-coenzyme A racemase expression in various neoplasias and their precursor lesions. Although there have been a few reports regarding alpha-methylacyl-coenzyme A racemase expression in
Ikuo Sekine et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 1(1), 31-37 (2007-04-06)
To find candidate genes for a predictive chemosensitivity test in patients with lung cancer by using a literature review. Using MEDLINE searches, "in vitro chemosensitivity associated genes" and articles on association of the gene alteration with clinical chemosensitivity in lung
Sanne E Blinde et al.
Diseases of the colon and rectum, 57(5), 578-584 (2014-05-14)
Inguinal lymph node metastasis is predictive of locoregional recurrence and poor overall survival in anal carcinoma. Metachronous lymph node metastasis occurs in 10% of all anal cancer patients, but multiple studies have shown that the benefit of elective irradiation of
Gunter von Minckwitz et al.
The Lancet. Oncology, 15(7), 747-756 (2014-05-06)
Preclinical data suggest that triple-negative breast cancers are sensitive to interstrand crosslinking agents, and that synergy may exist for the combination of a taxane, trastuzumab, and a platinum salt for HER2-positive breast cancer. We therefore aimed to assess the efficacy
Rui Niimi et al.
BMC cancer, 13, 309-309 (2013-06-27)
Neural-cadherin (N-cadherin) is one of the most important molecules involved in tissue morphogenesis, wound healing, and the maintenance of tissue integrity. Recently, the cleavage of N-cadherin has become a focus of attention in the field of cancer biology. Cadherin and
Piotr J Slomka et al.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 22(6), 1285-1295 (2015-02-24)
We aimed to evaluate the utility of fully automated software registration intended to improve CT attenuation correction (CTAC) map misalignments during cardiac (82)Rb PET/CT myocardial perfusion imaging (MPI). 171 consecutive patients (108 males, mean age 69 years), undergoing both rest-stress
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