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109-12-6
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关键词:'109-12-6'
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K S Iyer et al.
International journal of peptide and protein research, 39(2), 137-144 (1992-02-01)
The work reported herein describes our attempts to identify peptide immunogens of the beta-subunit of the pregnancy-specific placental hormone, human chorionic gonadotropin (hCG), capable of eliciting hormone specific and neutralizing antisera. Hydrophilicity profiles of the beta-subunits of hCG and the
L Pang et al.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 26(6), 781-781 (2019-11-02)
In invasive aspergillosis (IA), monitoring response to antifungal treatment is challenging. We aimed to explore if routine blood parameters help to anticipate outcomes following IA. Post hoc secondary analysis of two multicenter randomized trials was performed. The Global Comparative Aspergillosis
J E Stegner et al.
Journal of animal science, 82(4), 1016-1021 (2004-04-15)
Two progestin-based protocols for estrus synchronization in postpartum beef cows were compared following treatment administration on the basis of estrous response, interval to and synchrony of estrus, and pregnancy. Cows were assigned to one of the two treatment protocols by
Sandy C Lee et al.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 38(9), 2259-2273 (2019-01-01)
This pilot study evaluated use of contrast-enhanced ultrasound (CEUS) to reduce the number of benign breast masses recommended for biopsy. This prospective study included 131 consenting women, from October 2016 to June 2017, with American College of Radiology Breast Imaging
Binh Thanh Nguyen et al.
Electrophoresis, 37(23-24), 3146-3153 (2016-10-27)
An assay for protein kinase C delta (PKCδ) activity based on the quantification of a synthetic substrate using capillary electrophoresis with laser-induced fluorescence detection was developed. The peptides labeled with fluorescein isothiocyanate F-ERK (where ERK is extracellular signal-regulated kinase) and
Antonis Elia et al.
European journal of applied physiology, 121(3), 827-838 (2020-12-30)
This study examined the influence of dynamic apnoea training on splenic volume and haematological responses in non-breath-hold divers (BHD). Eight non-BHD performed ten maximal dynamic apnoeas, four times a week for six weeks. Splenic volumes were assessed ultrasonically, and blood
D Nicholas Bateman et al.
Lancet (London, England), 383(9918), 697-704 (2013-12-03)
Paracetamol poisoning is common worldwide. It is treated with intravenous acetylcysteine, but the standard regimen is complex and associated with frequent adverse effects related to concentration, which can cause treatment interruption. We aimed to ascertain whether adverse effects could be
A Durnez et al.
Histopathology, 49(2), 138-151 (2006-08-02)
Cytokeratin (CK) 7 and CK19 expression, present in hepatic progenitor cells (HPCs) and in cholangiocytes but not in normal hepatocytes, has been reported in some hepatocellular carcinomas (HCCs); however, the incidence and relevance of this expression in HCC in Caucasians
Meiyun Shi et al.
The Journal of pharmacy and pharmacology, 72(8), 1061-1071 (2020-04-30)
The purpose of this study is to reveal the pharmacokinetic profiles of astilbin with various doses in rats and investigate the oral absolute bioavailability and tissue distribution of astilbin after oral administration. Wistar rats were orally administered astilbin 12, 24 mg/kg
C Y Cheng et al.
Journal of medicinal chemistry, 35(12), 2243-2247 (1992-06-12)
(+-)-(5 beta,7 alpha,8 beta)-3,4-Dichloro-N-methyl-N-[3-methylene-2- oxo-8-(1-pyrrolidinyl)-1-oxaspiro[4,5]dec-7-yl]benzeneacetamide (14) and its (5 alpha,7 alpha,8 beta) diastereomer 15 have been synthesized from 1,4-cyclohexanedione monoethylene ketal (1) in 10 steps. Compound 14, which we have designated SMBU-1, was found to bind with moderate affinity (Ki
Josef Niebauer et al.
American journal of physiology. Heart and circulatory physiology, 285(2), H535-H540 (2003-02-25)
In this study, we assessed the effects of chronic exercise training (12 wk) on atherosclerotic lesion formation in hypercholesterolemic apolipoprotein E-deficient mice (n = 31). At the age of 9 wk, mice were assigned to the following groups: sedentary (Sed;
Yung-Kuo Lin et al.
Basic research in cardiology, 107(5), 293-293 (2012-08-14)
Obesity is an important risk factor for atrial fibrillation (AF). Increased epicardial adipose tissue in obesity can enhance inflammation and plays an important role in the pathophysiology of AF. However, it is not clear whether epicardial adipocytes directly modulate the
R Buchbinder et al.
Journal of clinical epidemiology, 53(10), 1013-1019 (2000-10-12)
A case-control study was performed to describe the clinical course and identify risk factors predisposing to the development of tiaprofenic acid associated cystitis. Cases were identified from reports to the Australian Adverse Drug Reactions Advisory Committee and a two-year (1995-1996)
Gaetano Lucisano et al.
Transplant international : official journal of the European Society for Organ Transplantation, 32(9), 949-959 (2019-04-14)
There are conflicting data about the role of transplant nephrectomy and immunosuppression withdrawal on the development of allosensitization and the impact on re-transplantation. We divided 109 first graft recipients into two groups according to whether they underwent nephrectomy (NX+, n = 61)
Franck Bielle et al.
The American journal of surgical pathology, 36(8), 1141-1149 (2012-07-14)
Peripheral neuroblastic tumors are the most commonly occurring extracranial tumors in children. Although a reliable diagnosis is achievable in the majority of cases, diagnosis of a minority of peripheral neuroblastic tumor cases (especially undifferentiated neuroblastoma) poses a challenge compared with
Leslie Citrome et al.
Journal of affective disorders, 151(2), 409-417 (2013-07-31)
This is a quantitative review of existing studies of transdermal selegiline for major depressive disorder. Data for dichotomous outcomes were extracted from the five 6-8 week studies of transdermal selegiline. Number needed to treat (NNT) vs. placebo was calculated for
L Thielemans et al.
Brain research, 895(1-2), 119-128 (2001-03-22)
Our laboratory has described the presence of motilin receptors in the rabbit cerebellum. We discovered its presence in the human TE671 cell line, which is of cerebellar origin. Cytosolic Ca(2+) fluxes were monitored on a confocal microscope in cells loaded
Carmen Tenorio-Jiménez et al.
Nutrients, 11(8) (2019-08-03)
Previous studies have reported that probiotics may improve clinical and inflammatory parameters in patients with obesity and metabolic syndrome (MetS). Lactobacillus (L.) reuteri V3401 has shown promising results on the components of MetS in animal studies. We aimed to evaluate
R Okimoto et al.
Genetics, 130(3), 471-498 (1992-03-01)
The nucleotide sequences of the mitochondrial DNA (mtDNA) molecules of two nematodes, Caenorhabditis elegans [13,794 nucleotide pairs (ntp)], and Ascaris suum (14,284 ntp) are presented and compared. Each molecule contains the genes for two ribosomal RNAs (s-rRNA and l-rRNA), 22
K Rautavuoma et al.
Matrix biology : journal of the International Society for Matrix Biology, 19(1), 73-79 (2000-02-25)
Lysyl hydroxylase (LH) catalyzes the formation of hydroxylysine in collagens and related proteins by the hydroxylation of lysine residues in peptide linkages. Three isoenzymes of LH have so far been characterized. We report here that the human LH3 gene is
Dong Eon Moon et al.
Pain physician, 18(2), E163-E170 (2015-03-21)
Epidural neuroplasty using the Racz catheter has a therapeutic effect in patients with cervical disc herniation and central stenosis who do not respond to fluoroscopically guided epidural injections. To evaluate the clinical outcomes of cervical epidural neuroplasty in patients with
Alexander Averyanov et al.
Stem cells translational medicine, 9(1), 6-16 (2019-10-16)
Previous phase I studies demonstrated safety and some beneficial effects of mesenchymal stem cells (MSCs) in patients with mild to moderate idiopathic pulmonary fibrosis (IPF). The aim of our study was to evaluate the safety, tolerability, and efficacy of a
S M Ensminger et al.
Journal of immunology (Baltimore, Md. : 1950), 167(1), 532-541 (2001-06-22)
Blockade of the CD40-CD154 pathway can inhibit CD4(+) T cell activation but is unable to prevent immune responses mediated by CD8(+) T cells. However, even in the absence of CD8(+) T cells, inhibition of the CD40-CD154 pathway is insufficient to
Ricardo J S Costa et al.
Journal of applied physiology (Bethesda, Md. : 1985), 126(5), 1281-1291 (2019-03-22)
It is commonly believed that gastrointestinal issues during exercise are exacerbated by hypohydration. This study aimed to determine the effect of exercise-induced hypohydration on gastrointestinal integrity, function, symptoms, and systemic endotoxin and inflammatory profiles. In a randomized crossover design, male
Francesco Liistro et al.
JACC. Cardiovascular interventions, 13(19), 2277-2286 (2020-09-21)
The aim of this study was to investigate the efficacy and safety of the Litos drug-coated balloon (DCB) versus plain old balloon angioplasty (POBA) for reduction of late lumen loss (LLL) in patients with critical limb ischemia undergoing below-the-knee (BTK)
David Devos et al.
Scientific reports, 9(1), 2918-2918 (2019-03-01)
Accurate patient stratification into prognostic categories and targeting Amyotrophic Lateral Sclerosis (ALS)-associated pathways may pave the way for promising trials. We evaluated blood-based prognostic indicators using an array of pathological markers. Plasma samples were collected as part of a large
Davide Seripa et al.
Diagnostic molecular pathology : the American journal of surgical pathology, part B, 15(3), 180-185 (2006-08-26)
Several protein and DNA-based methods have been previously described for the identification of apolipoprotein E isoforms or genotypes. However, all of them generate frequently false-positive results. The purpose of this study was to set up a new, simple, and effective
Chiung-Wen Hu et al.
Analytical and bioanalytical chemistry, 402(3), 1199-1208 (2011-11-19)
Since methylation at the N-7 and O(6) positions of guanine and the N-3 position of adenine in DNA are the predominant reaction sites, N(7)-methylguanine (N(7)-MeG), O(6)-methylguanine (O(6)-MeG), and N(3)-methyladenine (N(3)-MeA) have been suggested as good biomarkers for assessing exposure to
P F Kruse et al.
The Journal of cell biology, 42(1), 113-121 (1969-07-01)
Cell types in addition to those previously described (Kruse et al. 1963. J. Nat. Cancer Inst. 31:109; Kruse and Miedema. 1965. J. Cell Biol. 27:273) were found to form multiple-layered cultures by perfusion-culture technique. Dense populations containing 43 x 10(6)
Chee-Keong Toh et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 5(1), 17-22 (2009-10-31)
Epidermal growth factor receptor (EGFR) mutations are more common in lung adenocarcinoma and in female patients of East-Asian origin. We aimed to assess the expression of female hormone receptors in East-Asian lung adenocarcinomas, their correlation with EGFR mutations, and prognostic
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