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A Lin et al.
The Journal of biological chemistry, 258(17), 10664-10671 (1983-09-10)
The covalent structure of the rat liver 60 S ribosomal subunit protein L37 was determined. Twenty-four tryptic peptides were purified and the sequence of each was established; they accounted for all 111 residues of L37. The sequence of the first
Li-Juan Shen et al.
World journal of gastroenterology, 9(3), 459-462 (2003-03-13)
To investigate the change of HBV DNA, PCNA and GST-pi in chronic liver disease and hepatocellular carcinoma (HCC). Hepatitis B surface antigen (HBsAg), proliferating cell nuclear antigen (PCNA) and glutathione S-transferases (GST-pi) were detected by immunohistochemical staining and HBV DNA
S Andersson et al.
British journal of cancer, 85(8), 1153-1156 (2001-11-17)
Infection with the human papillomavirus is an important co-factor in the development of cervical carcinomas. Accordingly, HPV DNA is recognised in most of these tumours. Polymorphism of the p53 gene, codon 72, is also considered a risk factor in the
Haruka Takeshige-Amano et al.
Movement disorders : official journal of the Movement Disorder Society, 35(8), 1438-1447 (2020-05-02)
The objective of this study was to determine comprehensive metabolic changes of caffeine in the serum of patients with parkinsonian disorders including Parkinson's disease (PD), progressive supranuclear palsy (PSP), and multiple system atrophy (MSA) and to compare this with healthy
D Nicholas Bateman et al.
Lancet (London, England), 383(9918), 697-704 (2013-12-03)
Paracetamol poisoning is common worldwide. It is treated with intravenous acetylcysteine, but the standard regimen is complex and associated with frequent adverse effects related to concentration, which can cause treatment interruption. We aimed to ascertain whether adverse effects could be
Julio C Ricarte-Filho et al.
Cancer research, 69(11), 4885-4893 (2009-06-03)
Patients with poorly differentiated thyroid cancers (PDTC), anaplastic thyroid cancers (ATC), and radioactive iodine-refractory (RAIR) differentiated thyroid cancers have a high mortality, particularly if positive on [(18)F]fluorodeoxyglucose (FDG)-positron emission tomography (PET). To obtain comprehensive genetic information on advanced thyroid cancers
Kathleen M Gavin et al.
American journal of physiology. Endocrinology and metabolism, 304(11), E1167-E1174 (2013-03-28)
Estrogen has direct effects within adipose tissue and has been implicated in regional adiposity; however, the influence of estrogen on in vivo lipolysis is unclear. The purpose of this study was to investigate the effect of local 17β-estradiol (E(2)) on
P V Benos et al.
Genome research, 11(5), 710-730 (2001-05-05)
We present the sequence of a contiguous 2.63 Mb of DNA extending from the tip of the X chromosome of Drosophila melanogaster. Within this sequence, we predict 277 protein coding genes, of which 94 had been sequenced already in the
Janusz K Rybakowski et al.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 144B(6), 820-823 (2007-03-22)
Both serotonin transporter and brain-derived neurotrophic factor (BDNF) genes have been previously implicated in the efficacy of lithium prophylaxis. The aim of the present study was to assess a possible interaction between serotonin transporter genotype (5HTTLPR) and BDNF Val66Met polymorphism
Emmy D G Fleuren et al.
International journal of cancer, 133(2), 427-436 (2013-01-22)
Because novel therapeutic options are limited in Ewing sarcomas (ES), we investigated the expression, genetic aberrations and clinical relevance of MET and anaplastic lymphoma kinase (ALK) in ES and determined the relevance of targeting these receptors. MET and ALK protein
S-J Yin et al.
Journal of clinical pharmacy and therapeutics, 37(3), 364-369 (2011-09-15)
Cytochrome P450 2C19 (CYP2C19) and CYP2D6 are important xenobiotic metabolic enzymes and both show considerable genetic variability between Orientals and Caucasians. There are known marked heterogeneity in susceptibility to various cancers and hypertension among Chinese Mongolian, Hui and Han ethnic
Taru Lienemann et al.
BMC microbiology, 15, 131-131 (2015-07-02)
Salmonella enterica spp. enterica serotype Typhimurium (STM) is the most common agent of domestically acquired salmonellosis in Finland. Subtyping methods which allow the characterization of STM are essential for effective laboratory-based STM surveillance and for recognition of outbreaks. This study
David Neal Franz et al.
The Lancet. Oncology, 15(13), 1513-1520 (2014-12-03)
In the EXIST-1 trial, initiated on Aug 10, 2009, more than 35% of patients with subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis complex had at least 50% reduction in SEGA volume after 9·6 months of treatment with everolimus.
Ping Jin et al.
Zhonghua fu chan ke za zhi, 46(5), 329-332 (2011-07-08)
To investigate the effect of Interleukin (IL)-18, IL-12 and tumor necrosis factor-α (TNF-α) in hepatic injury in intrahepatic cholestasis of pregnancy (ICP). Sixty-two cases of ICP patients (ICP group), 30 cases of normal pregnant women (control group) and 30 cases
Peter A Coventry et al.
PLoS medicine, 17(8), e1003262-e1003262 (2020-08-20)
Complex traumatic events associated with armed conflict, forcible displacement, childhood sexual abuse, and domestic violence are increasingly prevalent. People exposed to complex traumatic events are at risk of not only posttraumatic stress disorder (PTSD) but also other mental health comorbidities.
National Toxicology Program genetically modified model report, (5)(5), 1-227 (2008-09-12)
Bromodichloromethane is a by-product of the chlorination of drinking water. It is formed by the halogen substitution and oxidation reactions of chlorine and naturally occurring organic matter (e.g., humic or fluvic acids) in water containing bromide. Bromodichloromethane was nominated to
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