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S J Lupton et al.
Journal of agricultural and food chemistry, 62(30), 7577-7585 (2014-07-16)
Heavy sows (n = 126) were treated with penicillin G procaine at a 5× label dose (33 000 IU/kg) for 3 consecutive days by intramuscular (IM) injection using three patterns of drug administration. Treatments differed by injection pattern and injection volume.
T Muzioł et al.
Acta biochimica Polonica, 48(4), 885-892 (2002-05-09)
The crystal structure of rat transthyretin (rTTR) complex with the dibromoflavone EMD21388 was determined to 2.3 A resolution and refined to R = 0.203 and Rfree = 0.288. Two different orientations of EMD21388, which differ in the channel penetration by
Philip E Bickler et al.
Brain research, 1340, 86-95 (2010-05-04)
Neurons preconditioned with non-injurious hypoxia or the anesthetic isoflurane express different genes but are equally protected against severe hypoxia/ischemia. We hypothesized that neuroprotection would be augmented when preconditioning with isoflurane and hypoxic preconditioning are combined. We also tested if preconditioning
Massimo Castagnola et al.
The Journal of biological chemistry, 279(40), 41436-41443 (2004-07-24)
The systematic search by tandem mass spectrometry of human saliva from four different subjects, of 136 possible fragments originated from histatin 3, allowed the detection of 24 different peptides. They include, with the exception of histatin 4, all the known
Pete Witucki et al.
Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 40(4), 345-350 (2013-08-21)
Decompression sickness (DCS) and central nervous system oxygen toxicity are inherent risks for "inside" attendants (IAs) of hyperbaric chambers. At the Hyperbaric Medicine Center at the University of California San Diego (UCSD), protocols have been developed for decompressing IAs. Protocol
Ying-Hui Li et al.
Analytical and bioanalytical chemistry, 375(6), 775-780 (2003-03-29)
Determination of low molecular weight organic acids in soils and plants by capillary zone electrophoresis was accomplished using a phthalate buffer and indirect UV detection mode. The influence of some crucial parameters, such as pH, buffer concentration and surfactant were
Qing Li et al.
Journal of cutaneous pathology, 31(10), 633-642 (2004-10-20)
S-phase kinase associated protein-2 (Skp2) ubiquitin ligase p45(SKP2) is important in the degradation of p27kip1 (a cyclin dependent kinase inhibitor) and progression through the G1-S cell-cycle checkpoint. Low levels of p27 and high levels of Skp2 are related to poor
O Bartsch et al.
Audiology & neuro-otology, 15(6), 375-382 (2010-03-18)
We report on 335 patients (319 families) with mild-to-profound nonsyndromic sensorineural hearing loss. We identified 178 mutated GJB2 alleles representing 29 different sequence changes (including 3 novel mutations: Q7P, N14D, H100Q), and 2 alleles with the deletion del(GJB6-D13S1830) of the
Ling Zeng et al.
International journal of molecular sciences, 22(22) (2021-11-28)
Myopia is the second leading cause of visual impairment globally. Myopia can induce sight-threatening retinal degeneration and the underlying mechanism remains poorly defined. We generated a model of myopia-induced early-stage retinal degeneration in guinea pigs and investigated the mechanism of
E Clave et al.
Journal of immunotherapy (Hagerstown, Md. : 1997), 22(1), 1-6 (1999-01-30)
The curative effect of allogeneic bone marrow transplantation (BMT) is in part due to an alloresponse of donor lymphocytes against recipient leukemia termed the graft versus leukemia (GvL) effect. To identify target antigens for the GvL response on leukemia cells
Brigita Nograšek et al.
Journal of microbiology (Seoul, Korea), 53(8), 503-510 (2015-08-01)
Five strictly anaerobic Gram-negative bacterial strains, P4-65, P4-76(T), P5-60, P5-119, and P5-125, presumably belonging to the genus Prevotella were isolated from pig fecal samples. Strains were tested for various phenotypic traits and nearcomplete genome sequences were obtained and analyzed. Phylogenetic
Samuel Peña-Llopis et al.
Nature genetics, 44(7), 751-759 (2012-06-12)
The molecular pathogenesis of renal cell carcinoma (RCC) is poorly understood. Whole-genome and exome sequencing followed by innovative tumorgraft analyses (to accurately determine mutant allele ratios) identified several putative two-hit tumor suppressor genes, including BAP1. The BAP1 protein, a nuclear
Ali Khader et al.
Tropical medicine & international health : TM & IH, 19(2), 219-223 (2013-12-18)
The aim of this study was to use E-Health to report on 12-month, 24-month and 36-month outcomes and late-stage complications of a cohort of Palestine refugees with diabetes mellitus (DM) registered in the second quarter of 2010 in a primary
E Sekerina et al.
Journal of molecular biology, 301(4), 1003-1017 (2000-09-01)
The 131-amino acid residue parvulin-like human peptidyl-prolyl cis/trans isomerase (PPIase) hPar14 was shown to exhibit sequence similarity to the regulator enzyme for cell cycle transitions human hPin1, but specificity for catalyzing pSer(Thr)-Pro cis/trans isomerizations was lacking. To determine the solution
Dina Orazbayeva et al.
Journal of chromatography. A, 1555, 30-36 (2018-05-03)
A new, sensitive and simple method based on vacuum-assisted headspace solid-phase microextraction (Vac-HSSPME) followed by gas chromatography-mass-spectrometry (GC-MS), is proposed for the quantification of rocket fuel unsymmetrical dimethylhydrazine (UDMH) transformation products in water samples. The target transformation products were: pyrazine
Nils Tore Vethe et al.
Therapeutic drug monitoring, 36(1), 108-118 (2013-09-26)
The development of biomarkers describing the individual responses to the immunosuppressant mycophenolic acid (MPA) has focused on the target enzyme activity [inosine 5'-monophosphate dehydrogenase (IMPDH)]. An extended strategy is to quantify the metabolic consequences of IMPDH inhibition. The aim of
Noemie Mermet-Joret et al.
Developmental neurobiology, 77(1), 102-119 (2016-06-28)
Protein kinase C gamma (PKCγ) interneurons, located in the superficial spinal (SDH) and medullary dorsal horns (MDH), have been shown to play a critical role in cutaneous mechanical hypersensitivity. However, a thorough characterization of their development in the MDH is
Christian Borup et al.
The American journal of gastroenterology, 115(12), 2086-2094 (2020-08-03)
The diagnosis of bile acid diarrhea is often missed because the availability of the seleno-taurohomocholic acid (SeHCAT) test is limited. We aimed to compare the biomarkers 7α-hydroxy-4-cholesten-3-one (C4) and fibroblast growth factor 19 (FGF19) with the SeHCAT test. Patients with
Lasse G Lorentzen et al.
Redox biology, 24, 101226-101226 (2019-06-04)
Laminin is a major protein of the basement membrane (BM), a specialized extracellular matrix (ECM) of the artery wall. The potent oxidizing and nitrating agent peroxynitrous acid (ONOOH) is formed at sites of inflammation, and data implicate ONOOH in ECM
Benedikt Warth et al.
Rapid communications in mass spectrometry : RCM, 26(13), 1533-1540 (2012-05-29)
Mycotoxins regularly occur in food worldwide and pose serious health risks to consumers. Since individuals can be exposed to a variety of these toxic secondary metabolites of fungi at the same time, there is a demand for proper analytical methods
Deborah K Fletcher et al.
European journal of applied physiology, 111(7), 1329-1339 (2010-12-15)
Several studies investigating the effect of caffeine on immune function following exercise have used one large bolus dose of caffeine. However, this does not model typical caffeine consumption. Therefore, the purpose of this study was to investigate whether small repeated
Yuan-Ping Lin et al.
Theriogenology, 74(7), 1161-1178 (2010-08-24)
Early transcripts related to male development in chicken embryos and their expression profiles were examined. A total of 89 and 127 candidate male development transcripts that represented 83 known and 119 unknown non-redundant sequences, respectively, were characterized in an embryonic
María-Victoria Mateos et al.
The New England journal of medicine, 369(5), 438-447 (2013-08-02)
For patients with smoldering multiple myeloma, the standard of care is observation until symptoms develop. However, this approach does not identify high-risk patients who may benefit from early intervention. In this randomized, open-label, phase 3 trial, we randomly assigned 119
F Parivar et al.
Urology, 44(5), 705-709 (1994-11-01)
To determine the time course of urethral anastomotic healing after radical retropubic prostatectomy and its relationship to a positive margin at the anastomosis, the type of suture used, and the incidence of bladder neck contracture. In 119 consecutive patients a
Zhi-Lai Zhan et al.
Journal of pharmaceutical and biomedical analysis, 156, 340-348 (2018-05-12)
As a traditional processing method, sulfuring has been used in the processing of many traditional Chinese medicines (TCMs). Desulfuring, which has emerged in recent years, is a new method applied to sulfured herbs so they can comply with regulations regarding
Daljit Vudathala et al.
Journal of AOAC International, 95(4), 1016-1022 (2012-09-14)
A simple and highly sensitive LC/MS method was developed for the simultaneous determination of six ionophores--lasalocid, monensin, laidlomycin, maduramycin, salinomycin, and narasin--in feed. The procedure involved extraction of 1 g of feed with 4 mL of methanol-water (9 + 1
Roger Galve et al.
Analytical chemistry, 74(2), 468-478 (2002-01-29)
Trichlorophenols (TCP) eliminated by the urine can be considered as potential biomarkers of exposure of many chemicals (chlorophenols, chlorophenoxy acid herbicides, prochloraz, lindane, hexachlorobenzene, etc). High-throughput screening methods are necessary to carry out efficient monitoring programs that may help to
M L Fitzgerald et al.
The Biochemical journal, 342 ( Pt 2), 353-360 (1999-08-24)
In platelets and other secretory cells, protein kinase C (PKC) plays a role in exocytosis stimulated by physiological extracellular signals, although its linkage to the secretory machinery is poorly understood. We investigated whether Rab6, a GTP-binding protein that fractionates with
S L Solanki et al.
Anaesthesia and intensive care, 41(1), 51-56 (2013-02-01)
This randomised, double-blind study was designed to compare the duration of analgesia and adverse effects following intrathecal administration of dexmedetomidine or clonidine, both with bupivacaine, in trauma patients. Ninety adult trauma patients of American Society of Anesthesiologists physical status I-II
QingJian Liang et al.
Fish & shellfish immunology, 88, 284-292 (2019-03-09)
SAHH is an enzyme, playing a significant role in the catalyzation of the S-adenosyl homocysteine (SAH) into homocysteine (Hcy) and adenosine (Ado). However, little is known information of the enzyme in crustaceans. In the present study, SAHH cDNA was cloned
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