CN
Search Within
120-13-8
应用筛选条件
关键词:'120-13-8'
显示 1-30 共 108 条结果 关于 "120-13-8" 范围 论文
Hideaki Ogata et al.
Gan to kagaku ryoho. Cancer & chemotherapy, 40(6), 749-753 (2013-07-19)
Third-generation aromatase inhibitors(AIs)are now common in adjuvant hormone therapy for breast cancer in postmenopausal women. However, a suitable treatment has yet to be established for patients who develop cancer recurrence during or after adjuvant AI therapy. This prospective study evaluated
Francis M Hughes et al.
Journal of medicinal chemistry, 53(12), 4623-4632 (2010-05-21)
The neurotensin hexapapetide fragment NT(8-13) is a potent analgesic when administered directly to the central nervous system but does not cross the blood-brain barrier. A total of 43 novel derivatives of NT(8-13) were evaluated, with one, ABS212 (1), being most
Rebecca Jane Dearman et al.
Journal of applied toxicology : JAT, 29(3), 233-241 (2008-11-21)
A major constraint in the development of methods for the identification of chemical respiratory allergens is the continuing uncertainty regarding the mechanisms of this disease and in particular the role of IgE antibody. There is, however, increasing evidence that respiratory
Emma J Stevenson et al.
European journal of applied physiology, 117(11), 2321-2333 (2017-09-21)
The performance and physiological effects of isomaltulose and maltodextrin consumed intermittently during prolonged soccer-specific exercise were investigated. University soccer players (n = 22) performed 120 min of intermittent exercise while consuming 8% carbohydrate-electrolyte drinks (equivalent to ~ 20 g h Blood glucose and plasma insulin (both
L B Zhang et al.
Poultry science, 87(7), 1370-1376 (2008-06-26)
An experiment was conducted to determine the effects of different doses of liquid dl-2-hydroxy-4-methylthio butanoic acid (LMA) on growth performance and immune response in broiler chickens. In an arrangement with 4 graded levels of LMA to meet 80, 100, 120
C S Konkoy et al.
Journal of neurochemistry, 65(6), 2773-2782 (1995-12-01)
The metabolism of Met-enkephalin and cholecystokinin (CCK) 8-(sulfated) by intact microslices was studied in rat brain regions. Incubation of brain slices with Met-enkephalin (400 microM) resulted in a linear rate of disappearance of parent peptide and appearance of metabolic fragments
Leon Alexander Danyel et al.
Ultrasound in medicine & biology, 46(8), 1889-1895 (2020-05-23)
Transcranial color-coded duplex sonography (TCCS) and computed tomography angiography (CTA) are widely used to identify intracranial stenoses (ISs). We assessed concordance of IS grading between TCCS and CTA and proposed new TCCS criteria for severe IS ≥70%. One hundred two
Takeshi Machino et al.
Life sciences, 110(2), 86-92 (2014-07-02)
We aimed to investigate the anti-hypertensive effect of radiofrequency (RF) renal denervation (RDN) in an animal model of hypertension. RF energy was delivered to bilateral renal arteries through a 2 Fr catheter with opening abdomen in 8 spontaneously hypertensive rats
Bryony A McNeill et al.
Endocrinology, 150(10), 4777-4783 (2009-07-18)
Circulating concentrations of C-type natriuretic peptide (CNP) and a related amino terminal fragment (NTproCNP) were measured at weekly intervals from preconception to 3 wk postpartum in ewes with twins (n = 8) and nonpregnant ewes (n = 8). In contrast
Tetsuya Shindo et al.
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 43(3), 122-126 (2002-09-20)
The contents of barbaloin (BA), isoBA, aloin-dimers A, B, C, D and aloe-emodin (AE) in aloe drinks were investigated. BA and isoBA were detected in 30 of the 31 samples at the levels of 120-570 micrograms/mL and 120-580 micrograms/mL, respectively.
Takaki Yoshikawa et al.
Gan to kagaku ryoho. Cancer & chemotherapy, 38(12), 1909-1911 (2011-12-29)
This is a randomized phase II trial to evaluate non-inferiority of progression-free surviva(l PFS) by comparing S-1 and S-1/PSK for advanced or recurrent gastric cancer. Sample size was calculated to be 120. However, the trial was terminated because of slow
Jenica H Kakadia et al.
American journal of physiology. Endocrinology and metabolism, 319(3), E614-E628 (2020-08-04)
In cultured fetal liver cells, insulin-like growth factor (IGF) binding protein (IGFBP)-1 hyperphosphorylation in response to hypoxia and amino acid deprivation is mediated by inhibition of mechanistic target of rapamycin (mTOR) and activation of amino acid response (AAR) signaling and
Bernd Krock et al.
Marine drugs, 13(11), 6687-6702 (2015-11-04)
Two strains of Azadinium poporum, one from the Korean West coast and the other from the North Sea, were mass cultured for isolation of new azaspiracids. Approximately 0.9 mg of pure AZA-36 (1) and 1.3 mg of pure AZA-37 (2)
Min Geun Suh et al.
Bioscience, biotechnology, and biochemistry, 84(9), 1799-1809 (2020-05-26)
Various mixtures were prepared depending on the mixing ratio of Scutellaria baicalensis hot water extract (SB-HW), and Chrysanthemum morifolium ethanol extract (CM-E) and their anti-inflammatory activity were compared. Among them, SB-HW (80 μg/mL)/CM-E (120 μg/mL) or SB-HW (40 μg/mL)/CM-E (160 μg/mL) significantly inhibited LPS-stimulated
Zhi Shi et al.
Breast cancer research and treatment, 135(3), 737-747 (2012-08-28)
Drug resistance remains a major hurdle to successful cancer treatment. Many mechanisms such as overexpression of multidrug-resistance related proteins, increased drug metabolism, decreased apoptosis, and impairment of signal transduction pathway can contribute multidrug resistance (MDR). Recent studies strongly suggest a
Irene Lurkin et al.
PloS one, 5(1), e8802-e8802 (2010-01-26)
Recently a number of randomized trials have shown that patients with advanced colorectal cancer do not benefit from therapies targeting the epidermal growth factor receptor when their tumors harbor mutations in the KRAS, BRAF and PIK3CA genes. We developed two
David E Reuss et al.
Acta neuropathologica, 130(3), 407-417 (2015-06-20)
IDH wild type (IDHwt) anaplastic astrocytomas WHO grade III (AA III) are associated with poor outcome. To address the possibilities of molecular subsets among astrocytoma or of diagnostic reclassification, we analyzed a series of 160 adult IDHwt tumors comprising 120
M S Shypshyna et al.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 59(1), 117-123 (2013-05-30)
In co-culture of dorsal root ganglion (DRG) and dorsal horn (DH) neurons we studied the long-term depression (LTD) caused by 5 sec(-1) low-frequency stimulation (LFS) of DRG neurons. Dual whole-cell patch clamp recording in the pairs of DRG and DH
Afrida Rahman-Enyart et al.
Molecular neurobiology, 57(8), 3568-3588 (2020-06-17)
The neuregulins (Nrgs 1-4) are a family of signaling molecules that play diverse roles in the nervous system. Nrg1 has been implicated in the formation of synapses and in synaptic plasticity. Previous studies have shown Nrg1 can affect neurite outgrowth
Cameron J Mitchell et al.
Nutrients, 7(10), 8685-8699 (2015-10-28)
The differential ability of various milk protein fractions to stimulate muscle protein synthesis (MPS) has been previously described, with whey protein generally considered to be superior to other fractions. However, the relative ability of a whole milk protein to stimulate
Yoshikazu Ishii et al.
Antimicrobial agents and chemotherapy, 54(9), 3625-3629 (2010-07-08)
ME1071, a maleic acid derivative, is a novel specific inhibitor for metallo-beta-lactamases (MBL). In this study, the potentiation of ME1071 in combination with several beta-lactams was evaluated using MBL-producing Pseudomonas aeruginosa isolates. The rates of susceptibility of MBL producers to
Mathias Köberl et al.
Dalton transactions (Cambridge, England : 2003), 40(43), 11490-11496 (2011-09-29)
The treatment of the dimeric paddle-wheel (PW) compound [Mo(2)(NCCH(3))(10)][BF(4)](4)1 with oxalic acid (0.5 equiv.), 1,1-cyclobutanedicarboxylic acid (1 equiv.), 5-hydroxyisophthalic acid (1 equiv.) (m-bdc-OH) or 2,3,5,6-tetrafluoroterephthalic acid (0.5 or 1 equiv.) leads to the formation of macromolecular dicarboxylate-linked (Mo(2))(n) entities (n
Erika Hernández-Aquino et al.
World journal of gastroenterology, 23(24), 4354-4368 (2017-07-15)
To study the molecular mechanisms involved in the hepatoprotective effects of naringenin (NAR) on carbon tetrachloride (CCl4)-induced liver fibrosis. Thirty-two male Wistar rats (120-150 g) were randomly divided into four groups: (1) a control group (n = 8) that received
Suk-Jeong Kim et al.
Frontiers in physiology, 9, 412-412 (2018-05-17)
Metabolic syndrome is closely associated with higher risk of hypertension, cardiovascular disease (CVD), diabetes and stroke. The aim of the present study was to investigate the long-term effects of policosanol supplementation on blood pressure (BP) and the lipid profile in
Weidong Wang et al.
American journal of physiology. Renal physiology, 294(6), F1473-F1480 (2008-04-25)
The effect of endotoxemia (lipopolysaccharide, 2.5 mg/kg ip) was investigated in aquaporin (AQP) 1 knockout (KO) compared with wild-type (WT) mice. At baseline, KO mice exhibited higher water intake (WI) and urine output (UO). After endotoxemia, WI and UO remained
S K Kabra et al.
Indian pediatrics, 40(7), 612-619 (2003-07-26)
To document clinical profile of cystic fibrosis (CF) in Indian children and the prevalence of delta F508 mutation in these patients. Observational study. Pediatric chest clinic in an urban tertiary care center in north India. July 1995 to June 2002.
B Ezquieta et al.
Clinical genetics, 62(2), 181-188 (2002-09-11)
This study addresses the contributions of gene conversion and a founder effect to the distribution of the two most frequent severe point mutations of the 21-hydroxylase (21OH) gene causing congenital adrenal hyperplasia: the 655G splicing mutation at intron 2, and
Giseli S Rocha et al.
Ecotoxicology (London, England), 25(8), 1468-1477 (2016-10-23)
Copper is an essential metal for several physiological and metabolic processes, but a narrow range regulate its effect in phytoplankton cells. It can affect the production of biomolecules and be toxic at concentrations slightly above those required, e.g. decreasing photosynthesis
Ian S Reynolds et al.
Frontiers in oncology, 10, 1682-1682 (2020-09-29)
Mucinous adenocarcinoma of the rectum is an infrequently encountered histological subtype that is associated with an impaired response to chemoradiotherapy and a worse overall prognosis. A genomic profile analysis of mucinous rectal tumors has not yet been performed. The aim
Jordy P Pijl et al.
Clinical nuclear medicine, 44(2), 99-106 (2018-12-06)
To investigate the diagnostic performance of F-fluoro-2-deoxy-D-glucose (FDG) PET/ CT for the detection of an infection focus in patients with a bloodstream infection (BSI) and to identify factors influencing the diagnostic yield of FDG-PET/CT. This retrospective single-center study included 185
1/4