Hayden Wilson Stagg et al.
The journal of trauma and acute care surgery, 75(6), 1040-1046 (2013-11-22)
Burns induce systemic microvascular hyperpermeability resulting in shock, and if untreated, cardiovascular collapse. Damage to the endothelial cell adherens junctional complex plays an integral role in the pathophysiology of microvascular hyperpermeability. We hypothesized that doxycycline, a known inhibitor of matrix