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显示 1-30 共 32 条结果 关于 "124-17-4" 范围 论文
Jan Harder et al.
World journal of gastroenterology, 15(36), 4511-4517 (2009-09-25)
To analyze the pathogenetic role and potential clinical usefulness of the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2) in patients with advanced biliary tract cancer (BTC). EGFR and HER2 expression was studied in
Kristina Ryberg et al.
Contact dermatitis, 58(4), 199-209 (2008-03-21)
Contact allergy to textile dyes is not uncommon. The allergy is detected by patch testing patients with commercial patch test preparations. To investigate 8 disperse dyes (DDs) used for patch testing in the departments in Malmö and in Leuven and
J K Schmitt et al.
American journal of hypertension, 8(5 Pt 1), 520-523 (1995-05-01)
In a retrospective study we investigated the effects of altering treatment of type II diabetes mellitus from insulin to tolazamide on weight and blood pressure. In 17 patients, weight decreased from 136 +/- 6 to 131 +/- 6% of ideal
Olugbenga Alaba Williams et al.
Psychiatry research, 247, 317-322 (2016-12-13)
Conventional bedside tests of visuospatial function such as the Clock Drawing (CDT) and Intersecting Pentagons (IPT) lack consistency in delivery and interpretation. We compared performance on a novel test of visuospatial ability - the LSD - with the IPT, CDT
Hui Che et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 33(1), 11-22 (2014-01-10)
Aging is associated with the gradual cognitive decline and shows the typical senile plaque formation in the brain, which results from the aggregation of beta amyloid (Aβ) peptide following the abnormal proteolytic processing of amyloid precursor protein (APP) by β-secretase
Mohammad M H Abdullah et al.
The British journal of nutrition, 113(3), 435-444 (2015-01-23)
Dairy products are rich sources of an array of fatty acids (FA) that have been shown individually and in certain clusters to exert varying effects on cardiovascular health, for which the circulating lipid profile is a powerful biomarker. Whether the
Lalji K Gediya et al.
Journal of medicinal chemistry, 51(13), 3895-3904 (2008-06-12)
Novel mutual prodrugs (MPs) of ATRA (all- trans-retinoic acid) and HDIs (histone deacetylase inhibitors) ( 10, 13, 17- 19) connected via glycine acyloxyalkyl carbamate linker (AC linker) or through a benzyl ester linker (1,6-elimination linker) were rationally designed and synthesized.
Jie Wang et al.
Ai zheng = Aizheng = Chinese journal of cancer, 26(1), 58-63 (2007-01-16)
Flt-3 internal tandem duplication (Flt-3/ITD) in transmembrane region is the most frequently identified mutation in Flt-3 gene, which is the most frequently happened in acute myeloid leukemia (AML) and correlated to prognosis. This study was to explore the correlation of
De-zhao Liu et al.
Zhonghua yi xue za zhi, 92(37), 2597-2600 (2013-01-08)
To explore the effects of cromolyn sodium (CS) on intestinal ischemia-reperfusion (IIR) and its relationship with mast cell activation and protease-activated receptor 2 (PAR-2) expression. A total of 32 SD rats were randomly divided into 4 groups: sham-operated (S), intestinal
R M Corbo et al.
Molecular human reproduction, 10(8), 617-620 (2004-06-29)
Human apolipoprotein E is the most important supplier of the cholesterol precursor for steroid hormone production in steroidogenic tissues and therefore could play a role in the regulation of steroid hormone function and influence human reproduction. This hypothesis has been
Yukie Tsugoshi et al.
Chemico-biological interactions, 327, 109148-109148 (2020-06-09)
We investigated the inhibitory effects of 13 organophosphate esters (OPEs) and hydrolytic metabolites on the carboxylesterase activity of rat liver microsomes in vitro in order to examine whether there might be a potential impact on human health, and to elucidate
Vanessa Moraes Bezerra et al.
Autonomic neuroscience : basic & clinical, 162(1-2), 48-53 (2011-05-04)
In this study we assessed the role of Bezold-Jarisch reflex (BJR) in the regulation of blood pressure (BP) of malnourished (MN) and control rats (CN) with sino-aortic denervation (SAD). Fischer rats were fed diets containing either 6% (MN) or 15%
Yi Liu et al.
European journal of pharmacology, 530(1-2), 23-32 (2006-01-03)
TRPM8 belongs to the family of transient receptor potential channels and is activated by cooling and cooling agents, such as icilin and menthol. It is expressed in a subset of sensory neurons and is thought to be involved in thermosensation.
Cheng-Ying Ho et al.
Neuro-oncology, 15(1), 69-82 (2012-11-20)
Pilocytic astrocytoma (PA) is a World Health Organization grade I glioma that occurs most commonly in children and young adults. Specific genetic alterations have been described in PA, but the pathogenesis remains poorly understood. We studied microRNA (miRNA) alterations in
M J Gibson et al.
Animal reproduction science, 214, 106312-106312 (2020-02-24)
There is an epidemic in New Zealand of infectious bovine anaemia associated with Theileria orientalis Ikeda type, an obligate intracellular protozoan parasite. To establish whether T. orientalis Ikeda type infection adversely affects fertility of bulls used for natural mating, a
Amber L Beitelshees et al.
Human genomics, 6, 9-9 (2012-12-19)
Leukocyte count has been associated with blood pressure, hypertension, and hypertensive complications. We hypothesized that polymorphisms in the CXCL5 gene, which encodes the neutrophilic chemokine ENA-78, are associated with blood pressure in cardiovascular disease (CVD)-free adults and that these polymorphisms
Li-Hui Zhang et al.
Cardiovascular drugs and therapy, 29(3), 243-255 (2015-05-23)
The glucagon-like peptide-1 (GLP-1) has been shown to exert cardioprotective effects in animals and patients. This study tests the hypothesis that preservation of GLP-1 by the GLP-1 receptor agonist liraglutide or the dipeptidyl peptidase-4 (DPP-4) inhibitor linagliptin is associated with
Lourdes Ibáñez et al.
The Journal of clinical endocrinology and metabolism, 88(7), 3333-3338 (2003-07-05)
Ovarian hyperandrogenism, a key feature of polycystic ovary syndrome, is preceded by precocious pubarche (PP) (pubic hair < 8 yr) in some populations. We hypothesized that this earlier presentation may relate to increased androgen sensitivity, indicated by androgen receptor gene
Mohammad H Afsarian et al.
Journal of medical microbiology, 64(Pt 3), 248-253 (2015-01-18)
Burn intensive care unit (BICU) patients are specifically exposed to deep-seated nosocomial infections due to Candida albicans. Superficial carriage of C. albicans is a potential source of infection and dissemination, and typing methods could be useful to trace the different
Haruo Kanno et al.
PloS one, 14(9), e0223106-e0223106 (2019-09-27)
Percutaneous pedicle screw (PPS) can provide internal fixation of the thoracolumbar spine through a minimally invasive surgical procedure. PPS fixation has been widely used to treat various spinal diseases. Rigid fixation of PPS is essential for managing osteoporotic spine in
Yelko Rodríguez-Carrasco et al.
Journal of chromatography. A, 1270, 28-40 (2012-11-28)
A new analytical method for the rapid and simultaneous determination of ten mycotoxins including patulin, zearalenone and eight trichothecenes (nivalenol, fusarenon-X, diacetoxyscirpenol, 3-acetyl-deoxynivalenol, neosolaniol, deoxynivalenol, T-2 and HT-2) in wheat semolina has been developed and optimized. Sample extraction and purification
N A Sharif et al.
The Journal of pharmacy and pharmacology, 56(2), 197-203 (2004-03-10)
The pharmacological properties of [(3)H]-prostaglandin E(2) ([(3)H]-PGE(2)) binding to washed homogenates of hamster uterus were determined. Scatchard analysis of competition data yielded dissociation constants (K(d)s) of 30.9 +/- 5.6 nM (n = 3) and apparent receptor density (B(max)) of 25.25
Martin Reck et al.
The Lancet. Respiratory medicine, 7(5), 387-401 (2019-03-30)
The IMpower150 trial showed significant improvements in progression-free and overall survival with atezolizumab plus bevacizumab plus carboplatin plus paclitaxel (ABCP) versus the standard-of-care bevacizumab plus carboplatin plus paclitaxel (BCP) in chemotherapy-naive patients with non-squamous non-small-cell lung cancer. Here, we report
Maria S Tretiakova et al.
The American journal of surgical pathology, 28(1), 69-76 (2004-01-07)
Alpha-methylacyl-CoA racemase (AMACR) was first discovered by using cDNA microarray technology as a molecular marker for prostate cancer. Our recent microarray analysis of renal cell carcinomas showed a significant increase of AMACR mRNA levels in papillary renal cell carcinomas, but
Tao Jin et al.
DNA and cell biology (2020-10-17)
The role of secreted exosomes during dopaminergic (DA) neuron differentiation is still unknown. To investigate the roles of exosomes in DA neuron fate specification, we profiled exosomal microRNAs (miRNAs) during DA neuron differentiation of epiblast-derived stem cells (EpiSCs). There were
Prafull Raheja et al.
Hypertension (Dallas, Tex. : 1979), 60(2), 319-325 (2012-06-27)
Recent studies from our laboratory indicate that chlorthalidone triggers persistent activation of the sympathetic nervous system and promotes insulin resistance in hypertensive patients, independent of serum potassium. Mechanisms underlying these adverse effects of chlorthalidone remain unknown, but increasing evidence in
Dan Wang et al.
Zhonghua yi xue za zhi, 91(30), 2129-2131 (2011-11-19)
To study the STAT5 phosphorylation levels of erythropoietin receptor (EPOR) and thrombopoietin receptor (TPOR) in CD34(+)CD59(-) and CD34(+)CD59(+) bone marrow cells of the patients with paroxysmal nocturnal hemoglobinuria (PNH). The bone marrow mononuclear cells (BMMNC) were extracted from 23 PNH
T Nikawa et al.
European journal of biochemistry, 204(1), 381-393 (1992-02-15)
Cathepsin J has been partially purified [Liao, J. C. R. & Lenney, J. F. (1984) Biochem. Biophys. Res. Commun. 124, 909-916], but its detailed properties are still unknown. In this study, we have purified cathepsin J completely and characterized it.
Thomas H Darrah et al.
Metallomics : integrated biometal science, 1(6), 479-488 (2009-11-01)
We find anomalously high gadolinium (Gd) concentrations in the femoral head bones of patients exposed to chelated Gd, commonly used as a contrast agent for medical imaging. Gd is introduced in chelated form to protect patients from exposure to toxic
Jennifer G Robinson et al.
JAMA, 311(18), 1870-1882 (2014-05-16)
In phase 2 studies, evolocumab, a fully human monoclonal antibody to PCSK9, reduced LDL-C levels in patients receiving statin therapy. To evaluate the efficacy and tolerability of evolocumab when used in combination with a moderate- vs high-intensity statin. Phase 3
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