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显示 1-30 共 156 条结果 关于 "1286005" 范围 论文
Qiusha Tang et al.
PloS one, 9(9), e106483-e106483 (2014-09-05)
A practical and effective strategy for synthesis of Folate-NIR 797-conjugated Magnetic Albumin Nanospheres (FA-NIR 797-MAN) was developed. For this strategy, Magnetic Albumin Nanospheres (MAN), composed of superparamagnetic iron oxide nanoparticles (SPIONs) and bovine serum albumin (BSA), were covalently conjugated with
Jacob Joseph et al.
Nutrients, 5(8), 3235-3256 (2013-08-21)
Over the last four decades, abnormalities in the methionine-homocysteine cycle and associated folate metabolism have garnered great interest due to the reported link between hyperhomocysteinemia and human pathology, especially atherothrombotic cardiovascular disease. However, clinical trials of B-vitamin supplementation including high
Sachin Yadav et al.
Artificial cells, nanomedicine, and biotechnology, 43(2), 93-102 (2013-11-08)
Breast cancer accounts for 23% of all newly occurring cancers in women worldwide and represents 13.7% of all cancer deaths. Available chemotherapeutic agents are limited largely due to the low accumulation of chemotherapeutics at the tumors relative to their accumulation
Maika Kissei et al.
Drug metabolism and pharmacokinetics, 29(5), 367-372 (2014-04-04)
Folic acid (FA) is a water-soluble vitamin, and orally ingested FA is absorbed from the small intestine by the proton-coupled folate transporter (PCFT). In the present study, we investigated whether epigallocatechin gallate (EGCG), one of the tea catechins, affects the
Daniel E Roth et al.
The American journal of clinical nutrition, 100(6), 1587-1595 (2014-11-21)
Prenatal calcium and iron supplements are recommended in settings of low dietary calcium intake and high prevalence of anemia. However, calcium administration may inhibit iron absorption. To overcome calcium-iron interactions, we developed a multi-micronutrient powder containing iron (60 mg), folic
Cynthia K Colapinto et al.
The British journal of nutrition, 112(11), 1873-1881 (2014-10-09)
Fortification of select grain products with folic acid and periconceptional supplementation recommendations in Canada and the USA have improved folate status, and have been associated with a reduced risk of neural tube defects. In the present study, we aimed to
W Al-Darzi et al.
Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 20(9), 561-568 (2014-10-25)
Egypt has a high incidence of neural tube defects. Folic acid supplementation in the periconceptional period is known to lower the risk of such defects. This cross-sectional study aimed to measure the level of knowledge about periconceptional folic acid use
Lijun Pei et al.
Birth defects research. Part A, Clinical and molecular teratology, 103(1), 3-11 (2014-06-12)
Many studies have indicated that the reduced folate carrier gene (SLC19A1) is associated with an increased risk of neural tube defects (NTDs). However, the interaction between the SLC19A1 gene variant and maternal fever exposure and NTD risk remains unknown. The
Mattias Johansson et al.
Journal of the National Cancer Institute, 106(12), doi:10-doi:10 (2014-11-08)
The etiology of renal cell carcinoma (RCC) is only partially understood, but a metabolic component appears likely. We investigated biomarkers of one-carbon metabolism and RCC onset and survival. The European Prospective Investigation into Cancer and Nutrition (EPIC) recruited 385747 participants
Nikita L van der Zwaluw et al.
Neurology, 83(23), 2158-2166 (2014-11-14)
We investigated the effects of 2-year folic acid and vitamin B12 supplementation on cognitive performance in elderly people with elevated homocysteine (Hcy) levels. This multicenter, double-blind, randomized, placebo-controlled trial included 2,919 elderly participants (65 years and older) with Hcy levels
Jian-Zhuang Tan et al.
Journal of the science of food and agriculture, 95(1), 126-135 (2014-04-15)
The effects of dietary l-arginine (Arg) on immunosuppression following infectious bursal disease virus (IBDV) inoculation in broiler chickens were evaluated. The design of this study was a 5 × 2 factorial arrangement (n = 5) with five Arg concentrations (starter:
Roxana Daneshjou et al.
Blood, 124(14), 2298-2305 (2014-08-01)
The anticoagulant warfarin has >30 million prescriptions per year in the United States. Doses can vary 20-fold between patients, and incorrect dosing can result in serious adverse events. Variation in warfarin pharmacokinetic and pharmacodynamic genes, such as CYP2C9 and VKORC1
Jeffrey J Tomaszewski et al.
The Journal of urology, 191(4), 971-976 (2013-10-08)
A randomized, placebo controlled clinical trial of folic acid supplementation for the chemoprevention of colorectal adenoma revealed an increased incidence of prostate cancer in the treatment group. Limited data exist on postdiagnostic folate/folic acid intake and the risk of prostate
Suhair Sunoqrot et al.
Journal of controlled release : official journal of the Controlled Release Society, 191, 115-122 (2014-05-20)
Nanoparticle (NP)-based drug delivery platforms have received a great deal of attention over the past two decades for their potential in targeted cancer therapies. Despite the promises, passive targeting approaches utilizing relatively larger NPs (typically 50-200nm in diameter) allow for
Reiko Nishihara et al.
The American journal of clinical nutrition, 100(6), 1479-1488 (2014-11-21)
Although a higher consumption of alcohol, which is a methyl-group antagonist, was previously associated with colorectal cancer risk, mechanisms remain poorly understood. We hypothesized that excess alcohol consumption might increase risk of colorectal carcinoma with hypomethylation of insulin-like growth factor
Valproate and folic acid in pregnancy: associations with autism.
Peter Baxter
Developmental medicine and child neurology, 56(7), 604-604 (2014-06-14)
Folic Acid assay
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 48(3), 6689-6689 (2022)
Alvin Nursalim et al.
Acta medica Indonesiana, 45(2), 150-156 (2013-06-19)
to determine whether the administration of folic acid, vitamin B6 and vitamin B12 would lead to reduction of cardiovascular complication and mortality among CKD patients. a search was conducted on PubMed and Google. The selection of title and abstract was
Vanessa R da Silva et al.
American journal of physiology. Endocrinology and metabolism, 307(1), E93-101 (2014-05-16)
Low vitamin B-6 nutritional status is associated with increased risk for cardiovascular disease and certain cancers. Pyridoxal 5'-phosphate (PLP) serves as a coenzyme in many cellular processes, including several reactions in one-carbon (1C) metabolism and the transsulfuration pathway of homocysteine
Mingjun Xuan et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 15(11), 2255-2260 (2014-04-18)
The synthesis of an innovative self-propelled Janus nanomotor with a diameter of about 75 nm that can be used as a drug carrier is described. The Janus nanomotor is based on mesoporous silica nanoparticles (MSNs) with chromium/platinum metallic caps and
David W Baker et al.
Acta biomaterialia, 10(7), 2945-2955 (2014-04-15)
Plasticity of macrophage (MΦ) phenotypes exist in a spectrum from classically activated (M1) cells, to alternatively activated (M2) cells, contributing to both the normal healing of tissues and the pathogenesis of implant failure. Here, folate- and mannose-based optical probes were
Estelle Cateau et al.
Research in microbiology, 165(10), 847-851 (2014-12-03)
Stenotrophomonas maltophilia, a bacteria involved in healthcare-associated infections, can be found in hospital water systems. Other microorganisms, such as Free Living amoebae (FLA), are also at times recovered in the same environment. Amongst these protozoa, many authors have reported the
Suranjana Mukherjee et al.
PloS one, 10(2), e0118153-e0118153 (2015-02-28)
Natural Killer (NK) cells perform many functions that depend on actin assembly, including adhesion, chemotaxis, lytic synapse assembly and cytolysis. HS1, the hematopoietic homolog of cortactin, binds to Arp2/3 complex and promotes actin assembly by helping to form and stabilize
Folic acid or folinic acid for reducing side effects of methotrexate for people with rheumatoid arthritis.
Beverley Shea
Journal of evidence-based medicine, 6(3), 202-203 (2013-12-12)
Alan H Maurer et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(5), 701-704 (2014-04-16)
Folate receptor (FR) can be used as a therapeutic target because of its expression on different epithelial cancers, such as ovarian, non-small cell lung, endometrial, and breast cancer. Assessing FR expression in tumors may help to identify patients who can
Amir Al-Dabagh et al.
American journal of clinical dermatology, 14(3), 155-161 (2013-04-12)
Methotrexate (MTX) is an effective treatment for psoriasis but its use is limited by its toxicity. Folate supplementation can be used to reduce the adverse effects of MTX, though this may impact efficacy. The frequency of folic acid supplementation is
Shaolian Zhang et al.
The Analyst, 139(23), 6259-6265 (2014-10-15)
A highly sensitive and recyclable quartz crystal microbalance (QCM) biosensor was developed using chitosan (CS) and folic acid (FA), generating conjugates that are selectively recognized by MCF-7 cancer cell over-expressed folic acid receptors. The prepared CS-FA conjugate was characterized by
Van-Minh Le et al.
European journal of medicinal chemistry, 92, 882-889 (2015-02-14)
Traditional chemotherapeutic drugs remain the major treatment for advanced colorectal cancer. However, due to the lack of tumor specificity these drug also destroy healthy tissue and organs, which has been the main reason for treatment failure and mortality. Folate-based drug
Growth and nutrition in children with food allergy requiring amino acid-based nutritional formulas.
Karen A Robbins et al.
The Journal of allergy and clinical immunology, 134(6), 1463-1466 (2014-12-03)
Aline H Guariento et al.
International journal of cancer, 135(1), 7-18 (2013-12-05)
The steady increase in the incidence and mortality of hepatocellular carcinoma (HCC) signifies a crucial need to understand better its pathogenesis to improve clinical management and prevention of the disease. The aim of this study was to investigate molecular mechanisms
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