131-18-0

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关键词:'131-18-0'

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Segmental copy number loss in the region of Semaphorin 4D gene in patients with acetabular dysplasia.

Tomohisa Sekimoto et al.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 31(6), 957-961 (2013-01-22)

Acetabular dysplasia (AD) appears to be a multi-factorial disease, which may involve both genetic and environmental factors and whose pathogenesis remains obscure. The present study aims to identify a genetic variation that might confer risk of AD. We performed whole-genome

Relationship between plasma volume and essential blood constituents in patients with heart failure and preserved ejection fraction.

Candela Diaz-Canestro et al.

Clinical physiology and functional imaging, 40(2), 131-138 (2019-12-12)

Notwithstanding recent progress on molecular mechanisms underlying heart failure with preserved ejection fraction (HFpEF), multiple pathophysiological aspects of this condition including the basis of anaemia and other haematological disorders remain unresolved. In this study, we sought to determine the relationship

Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial.

Jonathan Ledermann et al.

The Lancet. Oncology, 15(8), 852-861 (2014-06-03)

Maintenance monotherapy with the PARP inhibitor olaparib significantly prolonged progression-free survival (PFS) versus placebo in patients with platinum-sensitive recurrent serous ovarian cancer. We aimed to explore the hypothesis that olaparib is most likely to benefit patients with a BRCA mutation.

Phase I Study of Vorinostat as a Radiation Sensitizer with 131I-Metaiodobenzylguanidine (131I-MIBG) for Patients with Relapsed or Refractory Neuroblastoma.

Steven G DuBois et al.

Clinical cancer research : an official journal of the American Association for Cancer Research, 21(12), 2715-2721 (2015-02-20)

(131)I-metaiodobenzylguanidine (MIBG) is a radiopharmaceutical with activity in neuroblastoma. Vorinostat is a histone deacetylase inhibitor that has radiosensitizing properties. The goal of this phase I study was to determine the MTDs of vorinostat and MIBG in combination. Patients ≤ 30

HLA-DRB1* alleles and temporomandibular joint erosion in patients with various rheumatic diseases.

L M J Helenius et al.

Scandinavian journal of rheumatology, 33(1), 24-29 (2004-05-06)

To investigate the association between HLA antigens and temporomandibular joint (TMJ) erosion, salivary composition, and focal sialadenitis in patients with rheumatic diseases. Eighty-four patients, 24 with rheumatoid arthritis (RA), 19 with mixed connective tissue disease (MCTD), 19 with ankylosing spondylitis

Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial.

Marcia S Brose et al.

Lancet (London, England), 384(9940), 319-328 (2014-04-29)

Patients with radioactive iodine ((131)I)-refractory locally advanced or metastatic differentiated thyroid cancer have a poor prognosis because of the absence of effective treatment options. In this study, we assessed the efficacy and safety of orally administered sorafenib in the treatment

Direct evidence of brown adipocytes in different fat depots in children.

Denise Rockstroh et al.

PloS one, 10(2), e0117841-e0117841 (2015-02-24)

Recent studies suggested the persistence of brown adipocytes in adult humans, as opposed to being exclusively present in infancy. In this study, we investigated the presence of brown-like adipocytes in adipose tissue (AT) samples of children and adolescents aged 0

Ferritin concentrations correlate to outcome of hematopoietic stem cell transplantation but do not serve as biomarker of graft-versus-host disease.

M Großekatthöfer et al.

Annals of hematology, 92(8), 1121-1128 (2013-04-23)

Clinical presentation and laboratory data are often too unspecific to distinguish the onset or activity of graft-versus-host disease (GvHD) from infections or toxicity. Antigen-presenting cells such as monocytes/macrophages and dendritic cells are involved in GvHD pathogenesis after allogeneic hematopoietic stem

Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: two open-label, randomised controlled trials.

Nicole U Stoffel et al.

The Lancet. Haematology, 4(11), e524-e533 (2017-10-17)

Current guidelines to treat iron deficiency recommend daily provision of ferrous iron divided through the day to increase absorption. However, daily dosing and split dosing might increase serum hepcidin and decrease iron absorption from subsequent doses. Our study aim was

[Tyrothricin powder in the treatment of cutaneous lesions].

C Bayerl et al.

Die Pharmazie, 59(11), 864-868 (2004-12-14)

The efficacy and tolerance of an antiseptic wound powder based on the antibiotic tyrothricin was investigated in a prospective, randomized multicenter trial in patients with posttraumatic and surgical cutaneous lesions. In 5 centers, 131 male and female patients from 18-85

Human cortical dysplasia and epilepsy: an ontogenetic hypothesis based on volumetric MRI and NeuN neuronal density and size measurements.

Marissa Andres et al.

Cerebral cortex (New York, N.Y. : 1991), 15(2), 194-210 (2004-08-07)

In epilepsy patients with cortical dysplasia (CD), this study determined the probable ontogenetic timing of pathogenesis based on the number, location and appearance of neurons. Magnetic resonance imaging (MRI) determined gray and white matter volumes of affected and non-affected cerebral

Effectiveness of regular versus glargine insulin in stable critical care patients receiving parenteral nutrition: a randomized controlled trial.

Mohammad Bagher Oghazian et al.

Pharmacotherapy, 35(2), 148-157 (2015-02-18)

To compare the effectiveness and safety of two glycemic control regimens in stable critical care patients receiving parenteral nutrition (PN). Prospective, randomized open-label clinical trial. Eligible postoperative critical care patients in the ICU began PN on the first to the

Alfaxalone for total intravenous anaesthesia in dogs undergoing ovariohysterectomy: a comparison of premedication with acepromazine or dexmedetomidine.

Georgina L Herbert et al.

Veterinary anaesthesia and analgesia, 40(2), 124-133 (2012-07-14)

To describe alfaxalone total intravenous anaesthesia (TIVA) following premedication with buprenorphine and either acepromazine (ACP) or dexmedetomidine (DEX) in bitches undergoing ovariohysterectomy. Prospective, randomised, clinical study. Thirty-eight healthy female dogs. Following intramuscular buprenorphine (20 μg kg(-1) ) and acepromazine (0.05

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