Sebastiao N Martins-Filho et al.
Lung cancer (Amsterdam, Netherlands), 145, 144-151 (2020-05-25)
Patient-derived xenografts (PDX) are useful preclinical models to study cancer biology and mechanisms of drug response/resistance, particularly in molecularly targetable tumors. However, PDX engraftment may not be stochastic. We investigated clinical, histological and molecular features associated with PDX engraftment in