Merck
CN
Search Within

146072

应用筛选条件
关键词:'146072'
显示 31-60 共 234 条结果 关于 "146072" 范围 论文
Gil M Penuliar et al.
Frontiers in microbiology, 6, 354-354 (2015-05-23)
Antimicrobial chemotherapy is critical in the fight against infectious diseases caused by Entamoeba histolytica. Among the drugs available for the treatment of amebiasis, metronidazole (MTZ) is considered the drug of choice. Recently, in vitro studies have described MTZ resistance and
Qingsi Li et al.
Journal of colloid and interface science, 555, 145-156 (2019-08-05)
Resin hemoperfusion is a life-saving treatment for drug intoxication or hepatic failure of patients. However, current resin adsorbents exhibit a limited hemocompatibility or low adsorption efficiency, representing a major roadblock to successful clinical applications. In this work, we developed a
G Bellisola et al.
The Analyst, 140(13), 4407-4422 (2015-05-20)
We proved the ability of Fourier Transform Infrared microspectroscopy (microFTIR) complemented by Principal Component Analysis (PCA) to detect protein phosphorylation/de-phosphorylation in mammalian cells. We analyzed by microFTIR human polymorphonuclear neutrophil (PMNs) leukocytes, mouse-derived parental Ba/F3 cells (Ba/F3#PAR), Ba/F3 cells transfected
Awanish Kumar et al.
Parasitology international, 64(4), 36-42 (2015-01-20)
Visceral leishmaniasis (VL) is a major fatal disease prevalent in North-East India, caused by a protozoan parasite Leishmania donovani. The parasite multiplies and thrives inside mammalian macrophages and is transmitted by the bite of the sandfly. Due to the unsatisfactory
Degang Wang et al.
Molecular medicine reports, 11(1), 175-181 (2014-10-24)
Preparations utilizing monoclonal antibodies against S100A4 provide useful tools for functional studies to investigate the clinical applications of the human S100A4 protein. In the present study, human S100A4 protein was expressed in Escherichia coli (E. coli) BL21 (DE3), successfully purified
Vincenzo Abbate et al.
Enzyme and microbial technology, 50(2), 130-136 (2012-01-10)
Novel biohybrid hydrogels based on bovine serum albumin (BSA) were synthesized by one-pot photopolymerization of chemically modified protein in the presence of N,N'-methylenebisacrylamide (MBA) as cross-linking agent under mild conditions. Two batches of methacrylated albumins were prepared by treating the
Xiaojia Huang et al.
Journal of separation science, 34(23), 3418-3425 (2011-11-05)
In this study, a new stir bar sorptive extraction (SBSE) coating based on poly(vinylphthalimide-co-N,N'-methylenebisacrylamide) monolith (SBSE-VPMB) was prepared. The influences of the contents of monomer in polymerization mixture and the percentage of porogen solvent on the extraction performance were investigated
Takaki Amamoto et al.
Chemical & pharmaceutical bulletin, 62(7), 649-653 (2014-07-06)
We have developed a general method for controlling molecular functions using a photodegradable hydrogel; gels containing molecules made from such materials are capable of release and activation by light stimulus. As the elimination of molecular leaching from the gel before
Yasuo Yoshimi et al.
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 12(4), 264-270 (2009-12-26)
The instability of enzymatic glucose sensors has prevented the development of a practical artificial pancreas for diabetic patients. We therefore developed an enzyme-free glucose sensor using the gate effect of a molecularly imprinted polymer (MIP). This sensor has the advantages
Vijayashankar Suganya et al.
Clinica chimica acta; international journal of clinical chemistry, 450, 210-219 (2015-08-25)
Autism is a complex developmental disability for which no specific diagnostic markers have been identified so far. The present study aimed to evaluate whether there is any abnormal protein(s) excreted in the urine of autistic children by proteome analysis which
Protein tyrosine phosphatase 1B (PTP1B) is involved in the defective erythropoietic function of carbamylated erythropoietin.
María Eugenia Chamorro et al.
The international journal of biochemistry & cell biology, 61, 63-71 (2015-02-11)
Barbara R Braams et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(18), 7226-7238 (2015-05-08)
Prior studies have highlighted adolescence as a period of increased risk-taking, which is postulated to result from an overactive reward system in the brain. Longitudinal studies are pivotal for testing these brain-behavior relations because individual slopes are more sensitive for
Orhan Hazer et al.
Talanta, 82(5), 1974-1979 (2010-09-30)
Poly(acrylamidoxime-co-2-acrylamido-2-methylpropane sulfonic acid) (PAMSA) hydrogel was prepared by copolymerization of acrylonitrile and 2-acrylamido-2-methylpropane sulfonic acid as monomer, N,N'-methylenebis(acrylamide) as crosslinking agent and potassium peroxodisulfate as initiator. Amidoximated copolymer network was prepared by the reaction of copolymer network with hydroxylamine hydrochloride.
Michael D Onken et al.
Cytoskeleton (Hoboken, N.J.), 71(12), 695-706 (2014-12-30)
Endothelial cells (ECs) line the microvasculature and constitute a barrier between the vessel lumen and surrounding tissues. ECs inform circulating immune cells of the health and integrity of surrounding tissues, recruiting them in response to pathogens and tissue damage. ECs
Facundo Mattea et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 105, 98-104 (2015-08-16)
A new polymeric dosimeter based on itaconic acid and N, N'-methylenebisacrylamide was studied. The preparation method, compositions of monomer and crosslinking agent and the presence of oxygen in the dosimetric system were analyzed. The resulting materials were irradiated with an
Li Chang et al.
ACS applied materials & interfaces, 10(34), 29010-29018 (2018-08-07)
Production of high-performance and stable low-cost copper (Cu)-based flexible transparent electrodes (FTEs) is urgently needed for the development of new-generation flexible optoelectronic devices, but it still remains challenging. Herein, we developed a facile approach to fabricate high-performance, ultra-stable Cu grid
Li Zhou et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(7), 2930-2935 (2014-12-17)
Facile growth of CuS nanowires through self-assembly and their application as building blocks for near-infrared light-responsive functional films have been demonstrated. It is found that DNA is a key factor in preparing the CuS material with defined nanostructure. An exclusive
Fei Liu et al.
American journal of physiology. Lung cellular and molecular physiology, 308(4), L344-L357 (2014-12-17)
Pathological fibrosis is driven by a feedback loop in which the fibrotic extracellular matrix is both a cause and consequence of fibroblast activation. However, the molecular mechanisms underlying this process remain poorly understood. Here we identify yes-associated protein (YAP) (homolog
Allisson Jhonatan Gomes Castro et al.
Biochimica et biophysica acta, 1850(1), 51-61 (2014-10-15)
The effect of in vivo treatment with ursolic acid (UA) on glycemia in hyperglycemic rats and its mechanism of action on muscle were studied. The UA effects on glycemia, glycogen, LDH, calcium and on insulin levels were evaluated after glucose
Kelsey I MacConaghy et al.
The Analyst, 140(18), 6354-6362 (2015-08-14)
We have developed a novel approach for DNA detection as well as genetic screening of mutations by uniquely combining DNA-responsive and optically diffracting materials. This approach entails the polymerization of a photonic crystal within a hydrogel network that alters the
Tomáš Ječmen et al.
Methods (San Diego, Calif.), 89, 128-137 (2015-08-04)
Protein-protein interactions play a central role in the regulation of many biochemical processes (e.g. the system participating in enzyme catalysis). Therefore, a deeper understanding of protein-protein interactions may contribute to the elucidation of many biologically important mechanisms. For this purpose
Jean Guglielminotti et al.
Anesthesiology, 122(5), 985-993 (2015-03-03)
Individual assessment of the amplitude of a physiologic reflex evoked by a standardized noxious test (SNT) before surgical stimulation has been suggested to predict movement upon the forthcoming surgical stimulation. This study aimed to compare the ability of pupillary dilatation
Varsha Singh et al.
American journal of physiology. Gastrointestinal and liver physiology, 307(6), G623-G631 (2014-07-26)
Probiotics, including Lactobacilli, are commensal bacteria that have been used in clinical trials and experimental models for the prevention and treatment of diarrheal disorders. Our previous studies have shown that Lactobacillus acidophilus (LA) and its culture supernatant (CS) stimulated Cl(-)/HCO3
Avisek Mahapa et al.
PloS one, 10(3), e0122168-e0122168 (2015-03-31)
SarA, a Staphylococcus aureus-specific dimeric protein, modulates the expression of numerous proteins including various virulence factors. Interestingly, S. aureus synthesizes multiple SarA paralogs seemingly for optimizing the expression of its virulence factors. To understand the domain structure/flexibility and the folding/unfolding
Marcio H M da Luz et al.
Journal of neurochemistry, 153(3), 377-389 (2020-01-18)
PrPC is a glycoprotein capable to interact with several molecules and mediates diverse signaling pathways. Among numerous ligands, laminin (LN) is known to promote neurite outgrowth and memory consolidation, while amyloid-beta oligomers (Aβo) trigger synaptic dysfunction. In both pathways, mGluR1
Ewa Moczko et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1124, 1-6 (2019-06-09)
Herein an approach to prepare molecularly imprinted polymer nanoparticles (nanoMIPs) with specific binding affinity for antibodies is reported. The process relied on the covalent immobilization of the template (whole immunoglobulin G (IgG), Fc domain of human IgG and peptide epitope)
Chin-Yin Lin et al.
Molecular medicine reports, 10(6), 3334-3342 (2014-09-23)
Koelreuteria formosana ethanolic extract (KFEE) is obtained from natural plants that are endemic to Taiwan. In a previous study, it was demonstrated that KFEE inhibited low-density lipoprotein (LDL) and prevented oxidized LDL‑induced apoptosis in endothelial cells. In the present study
Zijun Bie et al.
Analytica chimica acta, 834, 1-8 (2014-06-15)
Boronate affinity materials have attracted increasing attentions as sample enrichment platforms for glycoproteomic analysis in recent years. However, most of the boronate affinity materials that have already employed for proteomic analysis are suffering from apparent disadvantages, such as alkaline pH
David Valverde et al.
ChemSusChem, 12(17), 3996-4004 (2019-07-10)
The catalytic activity of Rose Bengal (RB) immobilized on supported ionic liquid (IL)-like phases was evaluated as a polymer-supported photocatalyst. In these systems, the polymer was designed to play a pivotal role. The polymeric backbone adequately modified with IL-like moieties
Zifu Li et al.
Langmuir : the ACS journal of surfaces and colloids, 31(23), 6282-6288 (2015-04-04)
Two distinct uniform hybrid particles, with similar hydrodynamic diameters and comparable zeta potentials, were prepared by copolymerizing N-isopropylacrylamide (NIPAM) and styrene. These particles differed in their styrene to NIPAM (S/N) mass ratios of 1 and 8 and are referred to
2/8