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14960
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关键词:'14960'
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K Yamamoto et al.
Carcinogenesis, 10(9), 1607-1611 (1989-09-01)
The carcinogenic activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine (BHP) was investigated in male Wistar rats administered bis(2-hydroxypropyl)amine (BHPA) mixed in powder diet at a concentration of 1%, and sodium nitrite (SN) dissolved in distilled water at concentrations of 0.15 and 0.3%
Y Konishi et al.
IARC scientific publications, (105)(105), 318-321 (1991-01-01)
The carcinogenic activity of endogenously synthesized N-nitroso-bis(2-hydroxy-propyl)amine (NDHPA) was investigated in male Wistar rats administered bis(2-hydroxypropyl)amine (DHPA), mixed into a powdered diet at a concentration of 1%, and NaNO2 dissolved in distilled water at concentrations of 0.15% and 0.3%, for
K A Johnson et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45(10), 1838-1845 (2007-05-18)
The repeated dose oral and dermal toxicity of diisopropanolamine (DIPA) was evaluated in rats and compared to the reported toxicity of the related secondary alcohol amine, diethanolamine (DEA). Fischer 344/DuCrl rats were given up to 750 mg/kg/day by dermal application
L M Gieg et al.
Canadian journal of microbiology, 45(5), 377-388 (1999-08-14)
Diisopropanolamine (DIPA) is a "sweetening agent" used to remove hydrogen sulfide from sour natural gas, and it is a contaminant at some sour gas treatment facilities in western Canada. To investigate the biodegradation of this alkanolamine, 14C-DIPA was used in
Initiation activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine in the rat liver.
K Yamamoto et al.
Cancer letters, 45(3), 221-225 (1989-06-01)
The initiation potential of N-nitrosobis(2-hydroxypropyl)amine (NDHPA) endogenously synthesized from bis(2-hydroxypropyl)amine (DHPA) or tris(2-hydroxypropyl)amine (THPA) in the presence of sodium nitrite (NaNO2) was investigated in the rat liver by quantitation of hepatocellular foci showing phenotypic expression of glutathione S-transferase placental form
S A Saghir et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45(10), 2047-2056 (2007-06-23)
This study was conducted to determine the relative dermal bioavailability (absorption), distribution, metabolism, and excretion (ADME) of diisopropanolamine (DIPA), an alcohol amine used in a number of industrial and personal care products. Groups of 4 female Fischer 344 rats received
Bin Liu et al.
Oncology letters, 10(5), 2699-2704 (2016-01-02)
The aim of the present study was to investigate the expression, localization and role of centromere-associated protein E (Cenp-E) in hepatoma cells. The Cenp-E mRNA expression levels in the HepG-2 human hepatocellular carcinoma and LO2 normal hepatic cell lines following
Contact dermatitis due to diisopropanolamine.
K Fujimoto et al.
Contact dermatitis, 21(1), 56-56 (1989-07-01)
Two cases of contact dermatitis due to diisopropanolamine.
Yoshihiro Umebayashi
The Journal of dermatology, 32(2), 145-146 (2005-05-24)
W T Stott et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46(2), 761-766 (2007-11-09)
Aminoalcohols differ in mammalian toxicity at least in part based upon their ability to alter the metabolism of phospholipids and to cause depletion of the essential nutrient choline in animals. This study examined the incorporation of diisopropanolamine (DIPA) into phospholipids
Triple allergic contact sensitivities due to ferbinac, crotamiton and diisopropanolamine.
Naoki Oiso et al.
Contact dermatitis, 49(5), 261-263 (2004-03-05)
Inactivation of horseradish peroxidase by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine.
K Sugiyama et al.
Chemical research in toxicology, 7(6), 843-849 (1994-11-01)
In the presence of H2O2, horseradish peroxidase (HRP) catalyzes the one-electron oxidation of a porphyrinogenic agent, 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine (DDEP), leading to formation of an ethyl radical, inactivation of the enzyme, and formation of an altered heme product. The loss of heme
J Wilkinson et al.
Biochemical and biophysical research communications, 253(3), 855-858 (1999-01-27)
Regulation of the basal and induced expression of detoxifying enzymes such as NAD(P)H:quinone oxidoreductasel (NQO1) and glutathione S-transferase (GST) by the antioxidant response element (ARE) is important for cellular protection against oxidative stress. The ARE contains AP1 and AP1-like elements
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