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Matthias Treiber et al.
Journal of molecular medicine (Berlin, Germany), 84(12), 1015-1022 (2006-10-14)
Keratin 8 (KRT8) is one of the major intermediate filament proteins expressed in single-layered epithelia of the gastrointestinal tract. Transgenic mice over-expressing human KRT8 display pancreatic mononuclear infiltration, interstitial fibrosis and dysplasia of acinar cells resulting in exocrine pancreatic insufficiency.
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