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Nahla S Barakat et al.
Journal of microencapsulation, 25(1), 31-45 (2008-01-12)
The aim of this study was to develop and characterize diclofenac sodium loaded-cellulose acetate butyrate microparticles in order to obtain a controlled-release system. The influence of the type of polymer, the volume and composition of the internal phase, drug loading
Yasunori Miyazaki et al.
Biological & pharmaceutical bulletin, 26(12), 1744-1747 (2003-12-04)
Mucoadhesive microspheres made of oppositely charged dextran derivatives and cellulose acetate butyrate (Ad-MS) were evaluated for their ability to improve the bioavailability of theophylline (TH) and thiamine disulfide (TDS). A drug suspension (or solution) and non-adhesive microspheres (MS) were used
Wasfy M Obeidat et al.
Journal of microencapsulation, 24(3), 263-273 (2007-04-25)
The dispersion/incorporation of Eudragit S100 powder as a filler in cellulose acetate butyrate (CAB-551-0.01) microsphere containing theophylline was investigated as a means of controlling drug release. Microspheres of CAB-551-0.01 of different polymer solution concentrations/viscosities were prepared (preparations Z(0), Z(A), Z(B)
Yasunori Miyazaki et al.
Drug development and industrial pharmacy, 29(7), 795-804 (2003-08-09)
The objective of this study was to evaluate the utility of mixtures among oppositely charged dextran derivatives as constituents of a controlled release microsphere. Carboxymethyldextran (CMD) and dextran sulfate (DS) were used as polyanions, and [2-(diethylamino) ethyl] dextran (EA) and
Varaporn Buraphacheep Junyaprasert et al.
International journal of pharmaceutics, 352(1-2), 81-91 (2007-12-07)
A sustained release suspension of diltiazem, a short half-life calcium channel blocker, was developed to reduce frequency of drug administration, ease of dose adjustment and improve patient compliance. In this study, the sustained release of diltiazem was obtained by complexing
Mitra Jelvehgari et al.
Archives of pharmacal research, 32(7), 1019-1028 (2009-07-31)
The present research work compares the effect of microsphere preparation technique on micromeritics and release behaviors of theophylline microspheres. Microspheres were prepared by oil-in oil (O(1)/O(2)) emulsion solvent evaporation method (ESE) using different ratios of anhydrous theophylline to cellulose acetate
Chenyang Xing et al.
Carbohydrate polymers, 92(2), 1921-1927 (2013-02-13)
The eco-friendly poly(propylene carbonate) (PPC)/cellulose acetate butyrate (CAB) blends were prepared by melt-blending in a batch mixer for the first time. PPC and CAB were partially miscible because of the drastically shifted glass transition temperatures of both PPC and CAB
Kelin Huang et al.
Journal of agricultural and food chemistry, 59(10), 5376-5381 (2011-04-02)
Cellulose acetate butyrate (CAB) and cellulose acetate propionate (CAP) were prepared homogeneously in a 1-allyl-3-methylimidazolium chloride (AmimCl) ionic liquid system from sugarcane bagasse (SB). The reaction temperature, reaction time, and molar ratio of butyric (propionic) anhydride/anhydroglucose units in the cellulose
Soad A Yehia et al.
Drug delivery, 18(8), 620-630 (2011-11-25)
The purpose of this study is to increase the lag time and prevent release of budesonide, a corticosteroid drug used in Crohn's disease for the first 5 h and efficiently deliver it to the colon. Eudragit S100 spray-coated capsules and pulsatile
Gheorghe Fundueanu et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 66(1), 11-20 (2006-11-07)
The aim of this work is to safely transport bioadhesive microspheres loaded with DNA to intestine and to test their bioadhesive properties. Poly(vinyl alcohol) (PVA) microspheres were prepared by dispersion reticulation with glutaraldehyde and further aminated. These microspheres were firstly
M Constantin et al.
International journal of pharmaceutics, 330(1-2), 129-137 (2006-10-10)
Poly(vinyl alcohol) (PVA) microspheres were prepared by dispersion reticulation with glutaraldehyde and further aminated. These microspheres were firstly loaded with diclofenac (DF) and then entrapped in cellulose acetate butyrate (CAB) microcapsules by an o/w solvent evaporation technique for intestinal delivery
R B Umamaheshwari et al.
Drug delivery, 10(3), 151-160 (2003-08-29)
We prepared cellulose acetate butyrate (CAB)-coated cholestyramine microcapsules as a intragastric floating drug delivery system endowed with floating ability due to the carbon dioxide generation when exposed to the gastric fluid. The microcapsules also have a mucoadhesive property. Ion-exchange resin
Bei Xiang et al.
Journal of biomedical materials research. Part A, 95(1), 245-255 (2010-07-03)
Poly(ethylene-co-acrylic acid) (PE-co-AA) fibers in sizes of 200-500 nm were prepared by using a novel melt-extrusion-extraction fabrication process. The thermoplastic nanofibers could be controllably dispersed and reassembled by a novel solvent exchange filtration method. The dispersed PE-co-AA nanofibers possess active
Bibo Wang et al.
ACS applied materials & interfaces, 3(9), 3754-3761 (2011-08-24)
Ammonium polyphosphate (APP), a widely used intumescent flame retardant, has been microencapsulated by cellulose acetate butyrate with the aim of enhancing the water resistance of APP and the compatibility between the ethylene-vinyl acetate copolymer (EVA) matrix and APP. The structure
W M Obeidat et al.
Journal of microencapsulation, 22(3), 281-289 (2005-07-16)
The objectives of this investigation are to evaluate the encapsulation efficiency of the anti-thyroid agent 6-n-propyl-2-thiouracil using two polymers of different characteristics (cellulose acetate butyrate polymer, (CAB-551-0.01) and ammonio methacrylate copolymer (Eudragit RL 100) and to study the effect of
Min Soo Park et al.
Langmuir : the ACS journal of surfaces and colloids, 22(10), 4594-4598 (2006-05-03)
We investigate the effects of interfacial energy between water and solvent as well as polymer concentration on the formation of porous structures of polymer films prepared by spin coating of cellulose acetate butyrate (CAB) in mixed solvent of tetrahydrofuran (THF)
Yasunori Miyazaki et al.
International journal of pharmaceutics, 258(1-2), 21-29 (2003-05-20)
The objective of this study was to evaluate mucoadhesive properties and gastrointestinal transit of microspheres made of oppositely charged dextran derivatives and cellulose acetate butyrate (CAB). The microspheres were prepared by emulsion solvent evaporation method. A reference microsphere was made
Manuela C C M Sobral et al.
Journal of materials science. Materials in medicine, 19(2), 677-682 (2007-07-11)
Ketotifen was immobilised in cellulose acetate propionate (CAP) membranes and in cellulose acetate butyrate (CAB) membranes. The characteristics of each system were evaluated under a range of experimental conditions. The topography and uniformity of the membranes was assessed using scanning
Jun Wuk Park et al.
Macromolecular bioscience, 5(9), 840-852 (2005-09-02)
Miscible blends of PHB and CAB were prepared by the solvent-casting method with various blend compositions, and their orientation behavior was investigated during uniaxial drawing. X-ray analysis revealed that the orientation of the crystallizable PHB component in the drawn PHB/CAB
Soad A Yehia et al.
AAPS PharmSciTech, 10(1), 147-157 (2009-02-10)
The purpose of this study was to formulate budesonide (BUD) compression-coated tablets for colonic specific delivery. Pectin and guar gum were used as enzyme-dependent polymers. For comparison purposes, both pH- and time-dependent polymers were also tried. In vitro release studies
Gheorghe Fundueanu et al.
Biomaterials, 26(20), 4337-4347 (2005-02-03)
Sulfopropylated dextran microspheres (SP-Ms), (Dm = 80 microm) loaded with a water soluble drug (Tetracycline HCl), were included in cellulose acetate butyrate (CAB) microcapsules. Spherical CAB microcapsules were obtained by oil in water (o/w) solvent evaporation method in the presence
Chen Huang et al.
Journal of biomedical materials research. Part A, 101(1), 115-122 (2012-07-25)
Cellulose acetate butyrate nanofibers were prepared separately by two electrospinning techniques; a needleless electrospinning using a disc as spinneret and a rotary drum as collector and a conventional needle electrospinning using a rotary drum as collector. Compared to the needle-electrospun
Kazuyoshi Nakahashi et al.
Masui. The Japanese journal of anesthesiology, 52(1), 26-31 (2003-03-14)
Dental injuries are the most common reason for complaints against anesthetists. The purpose of this study was to investigate the effect of teeth protector on dental injuries during general anesthesia. Incidence of dental injuries was evaluated retrospectively in 5,946 consecutive
W M Obeidat et al.
Journal of microencapsulation, 21(1), 47-57 (2004-01-14)
Theophylline microspheres were prepared by the emulsion-solvent evaporation method using cellulose acetate butyrate (CAB381-20) and mixtures of CAB381-20(R) and cellulose acetate phthalate. The physical state of the drug, polymers and microspheres surfaces were determined using scanning electron microscopy. For those
Decheng Ma et al.
Journal of pharmaceutical and biomedical analysis, 35(4), 779-788 (2004-06-15)
The purpose of this study was to qualitatively and quantitatively determine potential cellulose acetate butyrate (CAB) extractables in a way to meaningfully predict the in vivo exposure resulting from clinical administration. Extractions of CAB-381-20 were performed in several solvent systems
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