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显示 1-30 共 36 条结果 关于 "200-123-1" 范围 论文
Noboru Harada et al.
Cellular and molecular neurobiology, 22(2), 207-226 (2002-10-05)
1. Interaction in the recognition of endothelin-1 (ET-1), a typical bivalent ET receptor-ligand, between ETA and ETB receptors was investigated in the rat anterior pituitary gland, using our quantitative receptor autoradiographic method with tissue sections preserving the cell-membrane structure and
Eric Larose et al.
Circulation. Heart failure, 2(5), 409-416 (2009-10-08)
Transplant coronary arteriosclerosis (TCA) is the principal long-term complication in cardiac transplant recipients. The mediators responsible for vascular proliferation and vasoconstriction typical of TCA remain largely unknown. We tested whether endothelin-1 (ET-1), a potent vasoconstrictor and mitogen, contributes to the
Hyun Wook Shin et al.
Journal of clinical laboratory analysis, 27(5), 379-383 (2013-09-17)
The measurement of fecal elastas-1 in stools is a sensitive and relatively inexpensive noninvasive test. The aim of this study was to study fecal elastase levels in patients who develop pancreatic leakage after pancreaticoduodenectomy (PD) to determine if fecal elastase
Martin M Maiwald et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 240, 118579-118579 (2020-07-10)
In the present work the complexation of Np(V) with sulfate in aqueous solution is studied in a temperature range up to 200 °C by absorption spectroscopy. For this purpose, a new spectroscopic setup is implemented and tested for its suitability for
G W Han et al.
Chemistry and physics of lipids, 71(2), 219-228 (1994-05-23)
At 123 K, the crystal structure of 1,2-dipalmitoyl-sn-glycerol (C35H68O5, M(r) = 568.9) is monoclinic with space group P2(1), a = 5.480(1), b = 7.301(1), c = 43.145(7) A, beta = 92.91(1) degrees, V = 1724 A3, Dc = 1.0960 g
K Takeuchi et al.
The Chinese journal of physiology, 42(3), 129-135 (2000-03-09)
Effects of endothelin-1 on gastric acid secretion, duodenal HCO3- secretion, and duodenal mucosal integrity were investigated in anesthetized rats, in comparison with those of TY-10957, a stable analogue of prostacyclin. A rat stomach mounted on an ex-vivo chamber or a
Linda Rydén et al.
Circulation, 130(23), 2005-2011 (2014-09-23)
Acute kidney injury (AKI) is a common complication after coronary artery bypass grafting (CABG) and is associated with adverse outcomes. However, the relationship between AKI after CABG and the long-term risk of end-stage renal disease (ESRD) is unknown. This study
Alla Khodorova et al.
Canadian journal of physiology and pharmacology, 88(6), 668-675 (2010-07-16)
A profound tachyphylaxis of the acute nocifensive flinching (pain) response to subcutaneous injection of endothelin-1 (ET-1) into the hind paw footpad is shown by the reduced response to a second injection. Flinching from the second injection was 20% +/- 5%
Michael D Cameron et al.
Drug metabolism and disposition: the biological fate of chemicals, 35(10), 1894-1902 (2007-07-25)
In vitro studies were conducted to elucidate the metabolic profiles of and the enzymes responsible for the metabolism of (R)- and (S)-tofisopam (1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine). Large differences were observed between the two enantiomers. The major metabolite in incubations of 500 ng/ml (approximately
A Rupin et al.
Thrombosis and haemostasis, 86(6), 1528-1531 (2002-01-05)
To investigate the role of active plasminogen activator inhibitor 1 (PAI-1) in the evolution of a microthrombus generated in the arteriolar microcirculation, the monoclonal antibody, 33H1F7, which transforms active PAI-1 to a tissue type plasminogen activator (t-PA) substrate, was evaluated
A Satoh et al.
Analytical biochemistry, 260(1), 96-102 (1998-07-02)
We have previously reported a method to immobilize protein ligands on microtiter plates coated with methyl vinyl ether-maleic anhydride copolymer (MMAC) [Isosaki, K., et al. (1992) J. Chromatogr. 597, 123-128]. In this study, we improved the MMAC method to efficiently
V N Mutafova-Yambolieva et al.
British journal of pharmacology, 123(1), 136-142 (1998-03-04)
1. The present study was undertaken to determine the modulatory effects of the endothelin peptides on the neurogenically-induced release of endogenous noradrenaline (NA) and the cotransmitter adenosine 5'-triphosphate (ATP) from the sympathetic nerves of endothelium-free segments of the rat isolated
Aline S C Fabricio et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 290(1), R164-R171 (2005-08-27)
Blockade of central endothelin ET(B) receptors inhibits fever induced by LPS in conscious rats. The contribution of ET(B) receptor-mediated mechanisms to fever triggered by intracerebroventricular IL-6, PGE2, PGF(2alpha), corticotropin-releasing factor (CRF), and preformed pyrogenic factor derived from LPS-stimulated macrophages (PFPF)
S Katti et al.
Insect molecular biology, 22(1), 31-40 (2012-11-06)
Many pheromones have very low water solubility, posing experimental difficulties for quantitative binding measurements. A new method is presented for determining thermodynamically valid dissociation constants for ligands binding to pheromone-binding proteins, using β-cyclodextrin as a solubilizer and transfer agent. The
Ryoji Ide et al.
Neuroscience letters, 507(1), 67-71 (2011-12-20)
We examined in infant rats whether cardiac afferent neurons in the nodose ganglia (NG) express transient receptor potential vanilloid 1 (TRPV1) receptors. Anesthetized rats (9-11 days old) were injected with 2 μl of a fluorescent retrograde tracer (Fluoro-Gold, FG) into
Junyu Lu et al.
Journal of chromatography. A, 1615, 460754-460754 (2019-12-10)
Biomedical sciences, and in particular disease biomarker research, demand highly selective and efficient glycoproteins/peptides enrichment platforms. In this work, a facile strategy to prepare hydrophilic maltose-functionalized magnetic metal-organic framework loaded with Au nanoparticles (denoted as magMOF@Au-maltose) for highly efficient enrichment
Nathan R Pillsbury et al.
The journal of physical chemistry. A, 113(17), 5013-5021 (2009-04-08)
Stimulated emission pumping-population transfer spectroscopy (SEP-PTS) has been used to directly measure the energy threshold to isomerization between the two conformational isomers of bis(2-hydroxyphenyl)methane. These conformers have been shown in the preceding paper (DOI 10.1021/jp8098686) to be an OH...O H-bonded
K T Vaughan et al.
The Journal of cell biology, 131(6 Pt 1), 1507-1516 (1995-12-01)
Cytoplasmic dynein is a retrograde microtubule motor thought to participate in organelle transport and some aspects of minus end-directed chromosome movement. The mechanism of binding to organelles and kinetochores is unknown. Based on homology with the Chlamydomonas flagellar outer arm
Noreen F Rossi
American journal of physiology. Endocrinology and metabolism, 286(4), E535-E541 (2003-12-11)
The endothelins (ET) have been implicated in vasopressin (AVP) release in vivo and in vitro. The effects of ET in this system are complex, and the net AVP secretory response likely depends on a unique combination of ET isoform, ET
A Parent et al.
Journal of neurophysiology, 79(6), 3295-3301 (1998-06-26)
Field potential recording was used to investigate properties of synaptic transmission and long-term potentiation (LTP) at Schaffer collateral-CA1 synapses in both hippocampal slices of mutant mice in which the alpha-subunit of the olfactory cyclic nucleotide-gated channel (alpha3/OCNC)1 was rendered null
N Guo et al.
Letters in applied microbiology, 58(4), 344-349 (2013-12-18)
Previous studies have shown that isoimperatorin (IO), a furanocoumarin isolated from several medicinal plants, has antimycobacterial activity against Mycobacterium tuberculosis strain H37Rv (ATCC 27294). This study demonstrated that IO has antimycobacterial activity against 2 drug-sensitive and 6 drug-resistant isolates, with
Carrie A Northcott et al.
American journal of physiology. Heart and circulatory physiology, 302(11), H2276-H2284 (2012-03-27)
Within the paraventricular nucleus (PVN), there is a balance between the excitatory and inhibitory neurotransmitters that regulate blood pressure; in hypertension, the balance shifts to enhanced excitation. Nitric oxide (NO) is an atypical neurotransmitter that elicits inhibitory effects on cardiovascular
Cristina T Kesler et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(9), 3668-3677 (2015-05-16)
The angiopoietin (Ang) ligands are potential therapeutic targets for lymphatic related diseases, which include lymphedema and cancer. Ang-1 and Ang-2 functions are established, but those of Ang-4 are poorly understood. We used intravital fluorescence microscopy to characterize Ang-4 actions on
Agostino Tafuri et al.
Blood, 100(3), 974-981 (2002-07-20)
Little is known about the prognostic role of multidrug resistance (MDR) in adults with newly diagnosed acute lymphoblastic leukemia (ALL). In the context of the GIMEMA ALL0496 protocol, we evaluated the impact of MDR1 (protein expression and function) on the
Anastasia Diakou et al.
PLoS neglected tropical diseases, 13(5), e0007003-e0007003 (2019-05-09)
The present study investigated the presence of endo- and ecto-parasites, and vector-borne pathogens, in dogs from four islands of Greece. A total of 200 (123 owned and 77 sheltered) dogs were examined with different microscopic, serological and molecular methods. Of
Erdal Alkan et al.
Urolithiasis, 43(3), 243-248 (2015-01-13)
The objective of the study was to ascertain whether flexible ureteroscopy with holmium laser lithotripsy and/or extraction of stone fragments is as effective in obese patients as in non-obese patients. The patients were divided into four groups (group 1: normal
Sin-Yu Yang et al.
Transplantation direct, 6(11), e620-e620 (2020-11-03)
Subcutaneous pouch is a potential site for islet transplantation. However, insufficient oxygen supply remains challenging. Pretreatment of neovascularization using basic fibroblast growth factor can solve this, but it needs 2× operations. We developed a device that contains rat islets in
Juan P Rigalli et al.
PLoS neglected tropical diseases, 6(12), e1951-e1951 (2012-12-29)
Benznidazole (BZL) is the only antichagasic drug available in most endemic countries. Its effect on the expression and activity of drug-metabolizing and transporter proteins has not been studied yet. Expression and activity of P-glycoprotein (P-gp), Multidrug resistance-associated protein 2 (MRP2)
Dahea You et al.
Molecular neurobiology, 56(10), 6986-7002 (2019-04-10)
Multidrug resistance protein 1 (MDR1, ABCB1, P-glycoprotein) is a critical efflux transporter that extrudes chemicals from the blood-brain barrier (BBB) and limits neuronal exposure to xenobiotics. Prior studies in malignant cells demonstrated that MDR1 expression can be altered by inhibition
Pedro Gomes Sanches et al.
Bone, 75, 62-71 (2015-02-15)
Bone is one of the most common metastatic target sites in breast cancer, with more than 200 thousand new cases of invasive cancer diagnosed in the US alone in 2011. We set out to establish a multimodality imaging platform for
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