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Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA.

M R Redinbo et al.

Biochemistry, 39(23), 6832-6840 (2000-06-08)

Human topoisomerase I helps to control the level of DNA supercoiling in cells and is vital for numerous DNA metabolic events, including replication, transcription, and recombination. The 2.6 A crystal structure of human topoisomerase I in noncovalent complex with a

Frequency of multi drug resistant Pseudomonas aeruginosa in different wound types of hospitalized patients.

Muhammad Ijaz et al.

Pakistan journal of pharmaceutical sciences, 32(2 (Supplementary)), 865-870 (2019-05-20)

Pseudomonas aeruginosa colonization is one of the major complications of wound infection leading to higher risk of morbidity and mortality. The trend of antibiotic resistant against Pseudomonas aeruginosa is increasing day by day due to irregular and extensive use of

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