5 mg
I-OMe-AG 538 658417 [a-Cyano-(3-methoxy,4-hydroxy,5-iodo)cinnamoyl-(3’,4’-
dihydroxyphenyl)ketone; Tyrphostin I-OMe-AG 538]
A cell-permeable and reversible analog of AG 538 (Cat. No.658403) that
E. coli. Specific activity: ≥5,000,000 units/mg
protein.
GSK3β, Active, Rat
(Catalogue No. 14-538)
An N-terminal GST-tagged rat GSK3β fusion protein
expressed in E. coli and purified by glutathione
OH
OH
O
AGL 2263
A cell-permeable benzoxazolone-containing bioisostere
of tyrphostin AG 538 (Cat. No. 658403) that acts as a
potent, substrate-competitive, but not ATP-competitive,
inhibitor
M0800 P n/d y y
536 p38 MAPK activated (diphosphorylated p38) M8177 M y y y
537 Negative Control NA
538 p53 P5813 M y n/d n/d
539 p53 P6874 M y n/d n/d
540 phospho-p53 (pSer392) P8982 P y y n/d
541 p53DINP1
26416, 1432, 81649 Mapk14,MAPK14 NP_036081.1,NP_620583.1,NP_112282.2 M y y y
537 Negative Control NA
538 p53 P5813 7157 TP53 NP_000537.3 M y n/d n/d
539 p53 P6874 7157 TP53 NP_000537.3 M y n/d n/d
540 phospho-p53
26416, 1432, 81649 Mapk14,MAPK14 NP_036081.1,NP_620583.1,NP_112282.2 M y y y
537 Negative Control
538 p53 P5813 7157 TP53 NP_000537.3 M y n/d n/d
539 p53 P6874 7157 TP53 NP_000537.3 M y n/d n/d
540 phospho-p53