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关键词:'209651'
显示 1-30 共 578 条结果 关于 "209651" 范围 论文
Robin M Skory et al.
Human reproduction (Oxford, England), 30(6), 1386-1395 (2015-03-19)
Can cultured follicles model the ovarian cycle, including follicular- and luteal-phase hormone synthesis patterns and ovulation? Under gonadotrophin stimulation, murine follicles grown in an encapsulated three-dimensional system ovulate in vitro and murine and human follicle hormone synthesis mimics follicular and
Ayano Oi et al.
The Journal of reproduction and development, 61(3), 191-197 (2015-03-06)
In this study, we examined the effects of reconstructed oocyte-granulosa cell complexes (OGCs) on the development of porcine oocytes derived from early antral follicles (EAFs; 0.5-0.7 mm in diameter). When denuded oocytes were cocultured with granulosa cells derived from other
Gang Li et al.
Journal of environmental sciences (China), 25(1), 144-154 (2013-04-17)
Element profile was investigated for their use to trace the geographical origin of rice (Oryza sativa L.) samples. The concentrations of 13 elements (calcium (Ca), potassium (K), magnesium (Mg), phosphorus (P), boron (B), manganese (Mn), iron (Fe), nickel (Ni), copper
Marco Vinceti et al.
Toxicology letters, 230(2), 295-303 (2013-11-26)
Selenium is a metalloid of considerable interest in the human from both a toxicological and a nutritional perspective, with a very narrow safe range of intake. Acute selenium intoxication is followed by adverse effects on the nervous system with special
Chih-Hung Chiang et al.
Cell transplantation, 24(3), 541-559 (2015-02-11)
Acute hepatic failure (AHF) is a severe liver injury leading to sustained damage and complications. Induced pluripotent stem cells (iPSCs) may be an alternative option for the treatment of AHF. In this study, we reprogrammed human dental pulp-derived fibroblasts into
Vivek Narayan et al.
The Journal of nutritional biochemistry, 26(2), 138-145 (2014-12-03)
Acetylation of histone and non-histone proteins by histone acetyltransferases plays a pivotal role in the expression of proinflammatory genes. Given the importance of dietary selenium in mitigating inflammation, we hypothesized that selenium supplementation may regulate inflammatory gene expression at the
Henrique V Almeida et al.
Advanced healthcare materials, 4(7), 1043-1053 (2015-02-07)
An alternative strategy to the use of in vitro expanded cells in regenerative medicine is the use of freshly isolated stromal cells, where a bioactive scaffold is used to provide an environment conducive to proliferation and tissue-specific differentiation in vivo.
G Bhuvanalakshmi et al.
Stem cell reviews, 10(6), 856-870 (2014-06-14)
The chick embryo represents an accessible and economical in vivo model, which has long been used in developmental biology, gene expression analysis, and loss/gain of function experiments. In the present study, we assessed and characterized bone marrow derived mesenchymal stem
Julia B Montgomery et al.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 76(4), 281-291 (2013-04-02)
The effects of selenium (Se) supplementation and source on equine immune function have not been extensively studied. This study examined the effects of oral Se supplementation and Se source on aspects of innate and adaptive immunity in horses. Fifteen horses
N Itami et al.
Theriogenology, 83(8), 1360-1367 (2015-03-01)
During oocyte growth, the number of mitochondria drastically increases and mitochondrial function profoundly affects the oocyte competence. Resveratrol is a well-known activator of sirtuin 1 (SIRT1), which has a role in cellular energy homeostasis and mitochondrial biogenesis. The main aim
Jianbing Zhang et al.
ACS nano, 9(7), 7151-7163 (2015-07-15)
We developed a strategy for producing quasi-spherical nanocrystals of anisotropic heterostructures of Cd/Pb chalcogenides. The nanostructures are fabricated via a controlled cation exchange reaction where the Cd(2+) cation is exchanged for the Pb(2+) cation. The cation exchange reaction is thermally
Jae-Yup Kim et al.
ACS nano, 9(11), 11286-11295 (2015-10-03)
Copper-indium-selenide (CISe) quantum dots (QDs) are a promising alternative to the toxic cadmium- and lead-chalcogenide QDs generally used in photovoltaics due to their low toxicity, narrow band gap, and high absorption coefficient. Here, we demonstrate that the photovoltaic performance of
Dolph L Hatfield et al.
Trends in biochemical sciences, 39(3), 112-120 (2014-02-04)
The many biological and biomedical effects of selenium are relatively unknown outside the selenium field. This fascinating element, initially described as a toxin, was subsequently shown to be essential for health and development. By the mid-1990s selenium emerged as one
Joshua R St Clair et al.
American journal of physiology. Heart and circulatory physiology, 309(3), H490-H498 (2015-05-24)
Pacemaker myocytes in the sinoatrial node of the heart initiate each heartbeat by firing spontaneous action potentials. However, the molecular processes that underlie pacemaking are incompletely understood, in part because of our limited ability to manipulate protein expression within the
Hossein Rahavi et al.
Journal of diabetes research, 2015, 878535-878535 (2015-04-22)
Regenerative and immunomodulatory properties of mesenchymal stem cells (MSCs) might be applied for type 1 diabetes mellitus (T1DM) treatment. Thus, we proposed in vitro assessment of adipose tissue-derived MSCs (AT-MSCs) immunomodulation on autoimmune response along with beta cell protection in
Beibei Chen et al.
Journal of chromatography. A, 1363, 62-70 (2014-08-19)
In this paper, the "state of the art" of chiral speciation of selenoamino acids (SeAAs) in biological samples is critically reviewed. The significance and the features of such studies are highlighted. A special focus lies on chiral speciation of SeAAs
Ken Ye et al.
PloS one, 9(6), e99410-e99410 (2014-06-12)
Infrapatellar fat pad adipose stem cells (IPFP-ASCs) have been shown to harbor chondrogenic potential. When combined with 3D polymeric structures, the stem cells provide a source of stem cells to engineer 3D tissues for cartilage repair. In this study, we
Simon Godin et al.
Journal of agricultural and food chemistry, 63(28), 6484-6492 (2015-07-15)
Two forms of selenium (Se) supplementation of fish feeds were compared in two different basal diets. A 12-week feeding trial was performed with rainbow trout fry using either a plant-based or a fish meal-based diet. Se yeast and selenite were
Courtney C Carignan et al.
Environmental health perspectives, 123(5), 500-506 (2015-02-24)
Previous studies indicate that concentrations of arsenic in breast milk are relatively low even in areas with high drinking-water arsenic. However, it is uncertain whether breastfeeding leads to reduced infant exposure to arsenic in regions with lower arsenic concentrations. We
Junhe Hu et al.
Zygote (Cambridge, England), 23(4), 615-621 (2014-07-06)
Previous studies have reported that the first polar body (PB1) morphology reflects embryo development competence, but the effects of PB1 on porcine embryo development remain unknown. This study aims to determine whether the ability of porcine embryo development is related
John Austin Milner, PhD (1947-2013).
Cindy D Davis et al.
The Journal of nutrition, 144(4), 411-413 (2014-02-07)
Narayana Kilarkaje
Cancer chemotherapy and pharmacology, 74(6), 1175-1189 (2014-09-23)
To investigate the effects of therapeutically relevant dose levels of bleomycin, etoposide and cisplatin (BEP) on testicular steroidogenic enzymes, and possible protective effects of an antioxidant cocktail (AC). Adult Sprague-Dawley rats received BEP with or without the AC (α-tocopherol, L-ascorbic
Irina I Popadyuk et al.
Bioorganic & medicinal chemistry, 23(15), 5022-5034 (2015-06-04)
We report the synthesis and biological activity of new semi-synthetic derivatives of naturally occurring deoxycholic acid (DCA) bearing 2-cyano-3-oxo-1-ene, 3-oxo-1(2)-ene or 3-oxo-4(5)-ene moieties in ring A and 12-oxo or 12-oxo-9(11)-ene moieties in ring C. Bioassays using murine macrophage-like cells and
Shawn P Grogan et al.
Tissue engineering. Part A, 20(1-2), 264-274 (2013-08-22)
Interaction between chondrocytes and the cartilage extracellular matrix (ECM) is essential for maintaining the cartilage's role as a low-friction and load-bearing tissue. In this study, we examined the influence of cartilage zone-specific ECM on human articular chondrocytes (HAC) in two-dimensional
Lizhen Yan et al.
Journal of chromatography. A, 1395, 173-179 (2015-04-14)
A new method for selenium speciation in fermented bean curd wastewater and juice was described. This method involved sample extraction with 5-sulfosalicylic acid (SSA)-functionalized silica-coated magnetic nanoparticles (SMNPs), capillary electrophoresis (CE) separation, and online detection with a modified electrothermal atomic
Doris Kuehnelt et al.
The American journal of clinical nutrition, 102(6), 1406-1415 (2015-11-06)
Selenium is an essential element, but its metabolism in humans is not well characterized. A few small studies indicate that the trimethylselenonium ion (TMSe) is a common selenium metabolite in humans. This study aimed to elucidate the human metabolism of
Robert K Huston et al.
PloS one, 10(8), e0136894-e0136894 (2015-09-01)
Previous studies of compatibility of calcium chloride (CaCl2) and phosphates have not included particle counts in the range specified by the United States Pharmacopeia. Micro-flow imaging techniques have been shown to be comparable to light obscuration when determining particle count
G M Silva et al.
Zygote (Cambridge, England), 23(4), 475-484 (2014-03-29)
The aim of this study was to evaluate the influence of two-dimensional (2D) and three-dimensional (3D) alginate culture systems on in vitro development of pre-antral caprine follicles. In addition, the influence of the reproductive age of the ovary donor on
Steven McClellan et al.
Methods (San Diego, Calif.), 82, 47-54 (2015-04-30)
Cancer stem cells (CSC) are a distinct subpopulation within a tumor shown to drive tumor progression, metastasis, and recurrence. A review of the literature reveals poor consensus, with the use of a wide variety of surface markers and functional assays
Atsushi Hamabe et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(43), 15526-15531 (2014-10-15)
Pyruvate kinase M2 (PKM2) is an alternatively spliced variant of the pyruvate kinase gene that is preferentially expressed during embryonic development and in cancer cells. PKM2 alters the final rate-limiting step of glycolysis, resulting in the cancer-specific Warburg effect (also
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