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Thomas Schmitt et al.
Journal of chemical ecology, 30(4), 731-740 (2004-07-21)
2-Methyl-1,4-benzoquinone (toluquinone) and 2-methoxy-3-methyl-1,4-benzoquinone are the most common components of defensive secretions of juliform millipedes (Diplopoda: Juliformia). A natural and a synthetic millipede-defensive secretion composed of these two substances attract dung beetles of a few Onthophagus species (Coleoptera: Scarabaeidae) that
J F Carroll et al.
Journal of chemical ecology, 31(1), 63-75 (2005-04-21)
Many mammals and birds roll on or rub themselves with millipedes that discharge benzoquinones. Chemicals transferred from millipedes onto the integument of anointing animals are thought to deter ectoparasites. We tested the lone star tick, Amblyomma americanum (L.), for responses
Svetlana Trivić et al.
Bioorganic chemistry, 30(2), 95-106 (2002-05-22)
In this communication, we have described the activation of several xenobiotics by glucose oxidase from Aspergillus niger. The following compounds are readily reduced by d-glucose, in the presence of glucose oxidase: p-nitroso-N,N-dimethylaniline, methyl-1,4-benzoquinone, and 7,7,8,8-tetracyano-quinodimethane. In each case, the products
Eduardo Mello De Capitani et al.
Clinical toxicology (Philadelphia, Pa.), 49(3), 187-190 (2011-04-19)
The most important millipede species causing accidents in Brazil is Rhinocricus padbergi (order Spirobolida, family Rhinocricidae), a vegetarian scavenger distributed from Central to South America. Eleven clinical cases of dermal and oral accidental exposures to secretions from Rhinocricus spp. milipedes
Ann Yezerski et al.
Journal of chemical ecology, 33(6), 1217-1225 (2007-05-03)
Many species of insects are known to produce and secrete benzoquinone derivatives. These compounds are usually defined as "defense chemicals." However, in many cases, it has not been determined what the chemicals are meant to defend against. Tribolium beetles produce
David Kokel et al.
Chembiochem : a European journal of chemical biology, 7(12), 2010-2015 (2006-10-20)
Benzene is a human carcinogen that might act through both genotoxic and nongenotoxic mechanisms to promote tumorigenesis. The genotoxic effects of benzene are well established, however, its potential nongenotoxic roles in carcinogenesis are poorly understood. We find that benzene suppresses
Francesca Capone et al.
Brain research bulletin, 58(2), 193-202 (2002-07-20)
In a previous study, mice were found to be repelled by the odour emitted by the millipede (Ommatoiulus sabulosus) as a defensive strategy against predators [Physiol. Behav. 74 (2001) 305-311]. To develop a standardised test for screening olfactory capabilities in
M Sato-Watanabe et al.
Biochemistry, 37(37), 12744-12752 (1998-09-16)
Cytochrome bo is a member of the heme-copper terminal oxidase superfamily and serves as a four-subunit ubiquinol oxidase in the aerobic respiratory chain of Escherichia coli. To probe the location and structural properties of the ubiquinol oxidation site, we isolated
A I Vovk et al.
Ukrainskii biokhimicheskii zhurnal (1978), 65(4), 11-16 (1993-07-01)
Inactivation kinetics of pyruvate decarboxylase under joint action of substrate and substituted quinones in aqueous solutions which contain 1.0-13.5 vol.% of methyl alcohol has been investigated. The observed inactivation rate constant of pyruvate decarboxylase sharply decreases with the increase of
C L Blankespoor et al.
Parasitology, 115 ( Pt 1), 105-110 (1997-07-01)
The defensive glands of beetles, Tenebrio molitor, infected with metacestodes (cysticercoids) of Hymenolepis diminuta are everted less frequently upon stimulation, and contain less toluquinone (methylbenzoquinone) and m-cresol, than glands of uninfected controls. These differences, as shown in predation trials with
Jiying Pei et al.
Journal of the American Society for Mass Spectrometry, 28(11), 2454-2461 (2017-08-09)
Unexpected reduction of iminoquinone (IQ) and quinone derivatives was first reported during positive electrospray ionization mass spectrometry. Upon increasing spray voltage, the intensities of IQ and quinone derivatives decreased drastically, accompanying the increase of the intensities of the reduction products
Nan Shu et al.
Free radical biology & medicine, 137, 169-180 (2019-04-27)
Quinones are a common motif in many biological compounds, and have been linked to tissue damage as they can undergo redox cycling to generate radicals, and/or act as Michael acceptors with nucleophiles, such as protein Cys residues, with consequent adduct
N K Cénas et al.
Biochimica et biophysica acta, 767(1), 108-112 (1984-10-26)
The rate constants of NADH oxidation by quinones are increased with the oxidation potential increase: log kox (M-1 X s-1) = -0.25 + 12.2 E0(7) (V) for o-quinones and log kox (M-1 X s-1) = -3.06 + 13.5 E0(7) (V)
Anthonia F Afolayan et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 63(11-12), 848-852 (2009-02-21)
In the course of our search for antimalarial leads from marine algae, four metabolites, sargaquinoic acid, sargahydroquinoic acid, sargaquinal and fucoxanthin, were isolated from the South African alga Sargassum heterophyllum. Fucoxanthin and sargaquinal showed good antiplasmodial activity toward a chloroquine-sensitive
Unexpected Reduction of Iminoquinone and Quinone Derivatives in Positive Electrospray Ionization Mass Spectrometry and Possible Mechanism Exploration.
Pei J, et al.
Journal of the American Society For Mass Spectrometry, 28(11), 2454-2461 (2017)
Michaela Bodner et al.
Chemoecology, 27(4), 171-175 (2017-08-15)
The defensive secretion of the julid diplopod
M Murata et al.
Biochemical and biophysical research communications, 261(2), 478-483 (1999-07-30)
Recently, the concern that toluene might have carcinogenic and reproductive toxic potential has been raised. We investigated the ability of DNA damage by minor metabolites of toluene, methylhydroquinone, and methylbenzoquinone, using (32)P-5'-end-labeled DNA fragments obtained from the human genes. Methylhydroquinone
Hurdles to organic quinone flow cells. Electrode passivation by quinone reduction in acetonitrile Li electrolytes.
Rueda-Garcia D, et al.
Journal of Power Sources, 350, 9-17 (2017)
Sanjeev Kumar et al.
Journal of medicinal chemistry, 51(6), 1706-1718 (2008-03-06)
Indoleamine 2,3-dioxygenase (IDO) is emerging as an important new therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression. While small molecule inhibitors of IDO exist, there remains a dearth of high-potency
Jianwei Li et al.
PLoS genetics, 9(7), e1003596-e1003596 (2013-07-23)
Chemical defense is one of the most important traits, which endow insects the ability to conquer a most diverse set of ecological environments. Chemical secretions are used for defense against anything from vertebrate or invertebrate predators to prokaryotic or eukaryotic
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