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Michele M Castro et al.
Free radical biology & medicine, 46(9), 1298-1307 (2009-03-03)
Mounting evidence indicates that structural and functional vascular changes associated with two-kidney, one-clip (2K-1C) hypertension result, at least in part, from altered activity of matrix metalloproteinases (MMPs). Because MMPs are upregulated by increased formation of reactive oxygen species (ROS), we
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