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Endothelial nitric oxide synthase gene is positively associated with essential hypertension.

Y Miyamoto et al.

Hypertension (Dallas, Tex. : 1979), 32(1), 3-8 (1998-07-23)

Essential hypertension has a genetic basis. Accumulating evidence, including findings of elevation of arterial blood pressure in mice lacking the endothelial nitric oxide synthase (eNOS) gene, strongly suggests that alteration in NO metabolism is implicated in hypertension. There are, however

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