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Qing Zhu et al.
Scientific reports, 6, 19266-19266 (2016-01-15)
Vitexin, a C-glycosylated flavone present in several medicinal herbs, has showed various pharmacological activities including antinociception. The present study investigated the antinociceptive effects of vitexin in a mouse model of postoperative pain. This model was prepared by making a surgical
Alain Lescoat et al.
Frontiers in immunology, 11, 219-219 (2020-03-07)
Inhalation of crystalline silica (SiO2) is a risk factor of systemic autoimmune diseases such as systemic sclerosis (SSc) and fibrotic pulmonary disorders such as silicosis. A defect of apoptotic cell clearance (i.e., efferocytosis, a key process in the resolution of
Guy Eelen et al.
Nature, 561(7721), 63-69 (2018-08-31)
Glutamine synthetase, encoded by the gene GLUL, is an enzyme that converts glutamate and ammonia to glutamine. It is expressed by endothelial cells, but surprisingly shows negligible glutamine-synthesizing activity in these cells at physiological glutamine levels. Here we show in mice
Dai Han et al.
Journal of integrative neuroscience, 18(3), 245-251 (2019-10-12)
The cognitive impairment associated with schizophrenia is highly prevalent and affects the overall functioning of subjects. The stimulation of the serotonin 1A receptor is a primary characteristic of some atypical antipsychotic drugs. We measured the levels of cognitive impairment using
Svetlana I Sofronova et al.
The Journal of endocrinology, 235(2), 137-151 (2017-08-11)
The mechanisms of vascular alterations resulting from early thyroid hormones deficiency are poorly understood. We tested the hypothesis that antenatal/early postnatal hypothyroidism would alter the activity of endothelial NO pathway and Rho-kinase pathway, which are specific for developing vasculature. Dams
Marine Chazalon et al.
Neuropharmacology, 138, 315-330 (2018-06-17)
Serotonin (5-HT) neurons are involved in wake promotion and exert a strong inhibitory influence on rapid eye movement (REM) sleep. Such effects have been ascribed, at least in part to the action of 5-HT at post-synaptic 5-HT1A receptors (5-HT1AR) in
Enthalpies of dilution of benzamide, cyclohexanecarboxamide, and N-acetyl-N′-methyl-l-cyclohexylalaninamide dissolved in N,N-dimethylformamide at 298.15 K.
The Journal of Chemical Thermodynamics, 21(12), 1301-1306 (1989)
Teresa L Parsons et al.
Journal of pharmaceutical and biomedical analysis, 98, 407-416 (2014-07-10)
Topical microbicidal agents are being actively pursued as a modality to prevent HIV viral transmission during sexual intercourse. Quantification of antiretroviral agents in specimen sources where antiviral activity is elicited is critical, and drug measurements in cervicovaginal fluid can provide
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