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Yu-Chi Chen et al.
Nutrients, 5(4), 1149-1168 (2013-04-10)
Selenium (Se) is an essential micronutrient that functions as a redox gatekeeper through its incorporation into proteins to alleviate oxidative stress in cells. Although the epidemiological data are somewhat controversial, the results of many studies suggest that inorganic and organic
Lucas A Lane et al.
The journal of physical chemistry. B, 118(49), 14140-14147 (2014-08-27)
Quantum dots (QDs) offer distinct advantages over organic dyes and fluorescent proteins for biological imaging applications because of their brightness, photostability, and tunability. However, a major limitation is that single QDs emit fluorescent light in an intermittent on-and-off fashion called
Joanna Slusarczyk et al.
Acta biologica Hungarica, 64(1), 96-105 (2013-04-10)
Mycelium of the white-rot fungus (Hericium erinaceum (Bull.: Fr. Pers.) produces polysaccharides showing anticancer and immunostimulating activity. In our previous works, we have shown that organic selenitetriglycerides (Selol) contribute to the increase of biosynthesis of exopolysaccharides (EPS) having antioxidative properties
Mona Navaei-Nigjeh et al.
Journal of biomedical materials research. Part A, 102(8), 2533-2543 (2013-08-22)
Nerve tissue engineering (NTE) is one of the most promising methods to restore central nerve systems in human health care. Three-dimensional (3D) distribution and growth of cells within the porous scaffold composed of nanofibers are of clinical significance for NTE.
Angélica Maciel Gomes et al.
Journal of cellular biochemistry, 116(8), 1668-1679 (2015-03-05)
The development of the mammary gland involves formation of a branched arboreal structure resulting from the penetration and proliferation of epithelial cells into the fat pad. The mammary cells invade by remodeling their surrounding extracellular matrix (ECM), which are rich
Arpit D Shah et al.
PloS one, 10(11), e0142337-e0142337 (2015-11-13)
Hepatocellular carcinoma (HCC) is the most common form of liver cancer (~80%), and it is one of the few cancer types with rising incidence in the United States. This highly invasive cancer is very difficult to detect until its later
Jeannette Molnár
Orvosi hetilap, 154(41), 1613-1619 (2013-10-08)
The author first summarizes briefly the antioxidant effects attributed to selenium. Literature data on the selenium supply in Hungary are reviewed in detail, also noting some important international reports. Hungarian soils are selenium deficient and this is reflected partly in
Tomoka Takatani-Nakase et al.
Biochemical and biophysical research communications, 463(1-2), 13-17 (2015-05-17)
Caspase-independent, non-apoptotic cell death is an important therapeutic target in myocardial ischemia. Leptin, an adipose-derived hormone, is known to exhibit cytoprotective effects on the ischemic heart, but the mechanisms are poorly understood. In this research, we found that pretreatment of
Lu Luo et al.
Biomedical materials (Bristol, England), 10(5), 055011-055011 (2015-09-24)
Bioreactors that subject cell seeded scaffolds or hydrogels to biophysical stimulation have been used to improve the functionality of tissue engineered cartilage and to explore how such constructs might respond to the application of joint specific mechanical loading. Whether a
Shuo Xiao et al.
Scientific reports, 5, 17323-17323 (2015-11-28)
In vitro follicle growth is a potential approach to preserve fertility for young women who are facing a risk of premature ovarian failure (POF) caused by radiation or chemotherapy. Our two-step follicle culture strategy recapitulated the dynamic human follicle growth
Silke Kuhfahl et al.
Biological chemistry, 396(3), 215-223 (2014-09-11)
The large proregions of cystine knot growth factors exert several important biological functions. Previous results have shown that the proregion of BMP2 retards the activity of the mature growth factor. Hitherto, no information exists about the function of the BMP2
Anna V Tugarova et al.
Microbial ecology, 68(3), 495-503 (2014-05-28)
The ability to reduce selenite (SeO(3)(2-)) ions with the formation of selenium nanoparticles was demonstrated in Azospirillum brasilense for the first time. The influence of selenite ions on the growth of A. brasilense Sp7 and Sp245, two widely studied wild-type
Christopher S Williams et al.
Carcinogenesis, 36(7), 710-718 (2015-04-29)
The ERBB4 receptor tyrosine kinase promotes colonocyte survival. Herein, we tested whether ERBB4's antiapoptotic signaling promotes transformation and colorectal tumorigenesis. ERBB4 alterations in a The Cancer Genome Atlas colorectal cancer (CRC) data set stratified survival, and in a combined Moffitt
Kai-Oliver Feldmann et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(27), 9697-9712 (2015-05-12)
Although a fairly large number of binary group 15/16 element cations have been reported, no example involving phosphorus in combination with a group 16 element has been synthesized and characterized to date. In this contribution is reported the synthesis and structural characterization
Ming-Li Chou et al.
PloS one, 9(6), e99145-e99145 (2014-06-20)
Clinical-grade ex vivo expansion of corneal endothelial cells can increase the availability of corneal tissues for transplantation and treatment of corneal blindness. However, these cells have very limited proliferative capacity. Successful propagation has required so far to use very complex
William A Banks et al.
Journal of neuroinflammation, 12, 223-223 (2015-11-27)
Disruption of the blood-brain barrier (BBB) occurs in many diseases and is often mediated by inflammatory and neuroimmune mechanisms. Inflammation is well established as a cause of BBB disruption, but many mechanistic questions remain. We used lipopolysaccharide (LPS) to induce
Reyhaneh Rahnama et al.
Environmental monitoring and assessment, 186(7), 4209-4216 (2014-03-05)
The developed method is based on cold-induced aggregation microextraction of Se(IV) using the 1-butyl-3-methylimidazolium hexafluorophosphate ionic liquid as an extractant followed by spectrophotometry determination. The extraction of Se(IV) was performed in the presence of dithizone as the complexing agent. In
Tiebing Liu et al.
PloS one, 10(7), e0133622-e0133622 (2015-07-18)
The etiology and pathophysiology of schizophrenia remain obscure. This study explored the associations between schizophrenia risk and serum levels of 10 trace elements. A 1:1 matched case-control study was conducted and matched by age and sex. Blood samples were collected
Alexander de Oliveira El-Warrak et al.
The Canadian veterinary journal = La revue veterinaire canadienne, 53(12), 1285-1288 (2013-06-05)
This study compared vitamin A, vitamin E, selenium (Se), and L-lactate in blood and synovial fluid in 2 groups of 6 dogs; a control group (without OA) and an osteoarthritic group with spontaneous cranial cruciate ligament rupture and OA. Concentrations
M W Roomi et al.
International journal of oncology, 44(3), 986-992 (2014-01-01)
Strong clinical and experimental evidence demonstrates association of elevated levels of matrix metalloproteinase MMP-9 with cancer progression, metastasis and shortened patient survival, as it plays a key role in tumor cell invasion and metastasis by digesting the basement membrane and
Matthew Loxham et al.
Toxicological sciences : an official journal of the Society of Toxicology, 145(1), 98-107 (2015-02-13)
We have previously shown that underground railway particulate matter (PM) is rich in iron and other transition metals across coarse (PM10-2.5), fine (PM2.5), and quasi-ultrafine (PM0.18) fractions and is able to generate reactive oxygen species (ROS). However, there is little
Kim De Nolf et al.
Journal of the American Chemical Society, 137(7), 2495-2505 (2015-01-30)
We investigate the relation between the chain length of ligands used and the size of the nanocrystals formed in the hot injection synthesis. With two different CdSe nanocrystal syntheses, we consistently find that longer chain carboxylic acids result in smaller
Frank Y Ma et al.
American journal of physiology. Renal physiology, 307(11), F1263-F1273 (2014-10-10)
Stress-activated kinases p38 MAPK and JNK promote renal fibrosis; however, how the pathways by which these kinases are activated in kidney disease remain poorly defined. Apoptosis signal-regulating kinase 1 (ASK1/MAPKKK5) is a member of the MAPKKK family that can induce
Paresh A Parmar et al.
Biomaterials, 54, 213-225 (2015-04-25)
Regenerative medicine strategies for restoring articular cartilage face significant challenges to recreate the complex and dynamic biochemical and biomechanical functions of native tissues. As an approach to recapitulate the complexity of the extracellular matrix, collagen-mimetic proteins offer a modular template
Yonghui Li et al.
Scientific reports, 5, 13149-13149 (2015-08-21)
Mesenchymal stem cells (MSCs) are pluripotent cells that primarily differentiate into osteocytes, chondrocytes, and adipocytes. Recent studies indicate that MSCs can also be induced to generate tenocyte-like cells; moreover, MSCs have been suggested to have great therapeutic potential for tendon
Tsz Kin Ng et al.
Scientific reports, 5, 16429-16429 (2015-11-10)
Retinal diseases are the leading causes of irreversible visual impairment and blindness in the developed countries. Human retina has limited regenerative power to replace cell loss. Stem cell replacement therapy has been proposed as a viable option. Previously, we have
Gurdarshan S Sandhu et al.
Seminars in oncology, 40(3), 276-285 (2013-06-29)
Prostate cancer is a leading cause of morbidity and mortality in men and has significant treatment-associated complications. Prostate cancer chemoprevention has the potential to decrease the morbidity and mortality associated with this disease. Chemoprevention research to date has primarily focused
Juan Li et al.
Molecular and cellular biology, 35(23), 4069-4082 (2015-09-24)
PTPN12 is a cytoplasmic protein tyrosine phosphatase (PTP) reported to be a tumor suppressor in breast cancer, through its capacity to dephosphorylate oncogenic receptor protein tyrosine kinases (PTKs), such as ErbB2. However, the precise molecular and cellular impact of PTPN12
Myong-Ho Jeong et al.
Nature communications, 5, 5455-5455 (2014-11-20)
Canonical Wnt signalling regulates expansion of neural progenitors and functions as a dorsalizing signal in the developing forebrain. In contrast, the multifunctional co-receptor Cdo promotes neuronal differentiation and is important for the function of the ventralizing signal, Shh. Here we
Lizette Utomo et al.
Biomedical materials (Bristol, England), 10(1), 015010-015010 (2015-01-15)
Scaffolds are widely used to reconstruct cartilage. Yet, the fabrication of a scaffold with a highly organized microenvironment that closely resembles native cartilage remains a major challenge. Scaffolds derived from acellular extracellular matrices are able to provide such a microenvironment.
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