230-442-1

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Acute toxicity of bupivacaine metabolites in mice.

B Bruguerolle et al.

Clinical and experimental pharmacology & physiology, 21(12), 997-999 (1994-12-01)

1. This study was designed to document the acute toxicity of two metabolites of bupivacaine, desbutylbupivacaine (2,6, desbutylbupivacaine; PPX) and pipecolic acid in mice. All the compounds were administered by the intraperitoneal (i.p.) route. 2. The mean convulsant activity was

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