approach for “precision
medicine.”
References:
Brooks, C.L. and Gu, W. Protein and Cell. 2011; 2: 456.
Levine, A.J., et al. Nat. Rev. Mol. Cell Biol. 2011; 12: 259.
Ozaki, T., and Nakagawara, A. Cancer
and time-dependent inhibitor (IC50 = 6.6 nM). Displays excellent selectivity against
a panel of 456 protein kinases. Diminishes autophosphorylation of BTK on Tyr223
in cells (EC50 = 475 nM) and promotes
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Class IIa Histone
Deacetylase (HDAC) Function in Health and Disease. Mol. Cell Proteomics. 2015; 14: 456-470.
Mitochondrial dysfunction: Franco-Iborra S, Vila M, Perier C. The Parkinson Disease Mitochondrial
17201 Mc3r NP_001020441.3,NP_032587.1 P n/d n/d y
455 MGMT M3068 4255 MGMT NP_002403.1 M y n/d n/d
456 Anti Cy3+Cy5
457 Mint2 M3319 83610, 321, 11784 APBA2,Apba2 NP_113968.1,NP_005494.2,NP_031487.1 P n/