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Mahtab Ahmad et al.
Bioresource technology, 143, 615-622 (2013-07-11)
In this study, pine needles were converted to biochar (BC) at different pyrolysis temperatures of 300, 500, and 700 °C to sorb trichloroethylene (TCE), and the changes in BC properties with each temperature were evaluated. Pyrolysis temperature showed a pronounced
Luoping Zhang et al.
Carcinogenesis, 34(4), 799-802 (2013-01-02)
Trichloroethylene (TCE) has been associated with a variety of immunotoxic effects and may be associated with an increased risk of non-Hodgkin lymphoma (NHL). Altered serum immunoglobulin (Ig) levels have been reported in NHL patients and in animals exposed to TCE.
A A Toropov et al.
European journal of medicinal chemistry, 43(4), 714-740 (2007-07-17)
Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and organic compounds of different classes by optimal descriptors. Statistical characteristics of the best model (vitamins) are the
Yunde Liu et al.
Chemosphere, 107, 94-100 (2014-05-31)
Dual isotope approach has been proposed as a viable tool for characterizing and assessing in situ contaminant transformation, however, little data is currently available on its applicability to chlorinated ethenes. This study determined carbon and chlorine isotope fractionation during Fenton-like
Yunde Liu et al.
Journal of contaminant hydrology, 145, 37-43 (2013-01-05)
Mineral-catalyzed Fenton-like oxidation of chlorinated ethylenes is an attractive technique for in situ soil and groundwater remediation. Stable carbon isotope enrichment factors associated with magnetite-catalyzed Fenton-like oxidation of trichloroethylene (TCE) have been determined, to study the possibility of applying stable
Federico Aulenta et al.
ChemSusChem, 6(3), 433-436 (2013-02-13)
Playing your part: Conductive magnetite nanoparticles accelerate the microbial reductive dechlorination of trichloroethene (TCE), an ubiquitous and toxic subsurface contaminant. The stimulatory effect most likely results from the nanoparticles promoting the establishment of interspecies electron transfer (IET) processes between non-dechlorinating
Shams Tabrez et al.
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews, 27(3), 178-196 (2009-08-07)
Trichloroethylene (TCE) is a prevalent occupational and environmental contaminant that has been reported to cause a variety of toxic effects. This article reviews toxicity, mutagenicity, and carcinogenicity caused by the exposure of TCE and its metabolites in the living system
Nagalakshmi Keshava et al.
Environmental health perspectives, 114(9), 1464-1470 (2006-09-13)
Peroxisome proliferator-activated receptor alpha (PPARalpha) is thought to be involved in several different diseases, toxic responses, and receptor pathways. The U.S. Environmental Protection Agency 2001 draft trichloroethylene (TCE) risk assessment concluded that although PPAR may play a role in liver
Svenja T Lohner et al.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 368(1616), 20120326-20120326 (2013-03-13)
The genome sequence of psychrophilic Shewanella sediminis revealed the presence of five putative reductive dehalogenases (Rdhs). We found that cell extracts of pyruvate/fumarate-grown S. sediminis cells catalysed reduced methyl viologen-dependent reductive dechlorination of tetrachloroethene (PCE) to trichloroethene (TCE) at a
Noreen Yaqoob et al.
Toxicology, 304, 49-56 (2012-12-06)
The industrial solvent trichloroethylene (TCE) has been reported to increase the excretion of formic acid in the urine of male Fischer 344 (F-344) rats following large oral doses. We have examined the dose-response relationship for formic aciduria in male and
Johnni Hansen et al.
Journal of the National Cancer Institute, 105(12), 869-877 (2013-06-01)
Trichloroethylene (TCE) is a widely used chlorinated solvent with demonstrated carcinogenicity in animal assays. Some epidemiologic studies have reported increased risk of cancer of the kidney, cervix, liver and biliary passages, non-Hodgkin lymphoma, and esophageal adenocarcinoma. We established a pooled
Todd S Webster et al.
Water research, 47(2), 811-820 (2012-12-05)
N-nitrosodimethylamine (NDMA) is a suspected human carcinogen that has traditionally been treated in water using ultraviolet irradiation (UV). The objective of this research was to examine the application of a laboratory-scale fluidized bed reactor (FBR) as an alternative technology for
Cevdet Züngün et al.
Clinical toxicology (Philadelphia, Pa.), 51(8), 748-751 (2013-07-31)
Long-term organic solvent exposure may cause toxic effects in central nervous system . Trichloroethylene (TCE) is known to be one of the neurotoxic chlorinated organic solvents. Trichloroacetic acid (TCA) is an oxidative pathway metabolite of TCE. S100B, a calcium-binding protein
J Christopher Corton
Critical reviews in toxicology, 38(10), 857-875 (2008-09-30)
Trichloroethylene (TCE) is an industrial solvent and a widespread environmental contaminant. Induction of liver cancer in mice by TCE is thought to be mediated by two metabolites, dichloroacetate (DCA) and trichloroacetate (TCA), both of which are themselves mouse liver carcinogens.
Denis Fourches et al.
Chemical research in toxicology, 23(1), 171-183 (2009-12-18)
Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this
Weihsueh A Chiu et al.
Environmental health perspectives, 121(3), 303-311 (2012-12-20)
In support of the Integrated Risk Information System (IRIS), the U.S. Environmental Protection Agency (EPA) completed a toxicological review of trichloroethylene (TCE) in September 2011, which was the result of an effort spanning > 20 years. We summarized the key
Hang Zhang et al.
Biochemical and biophysical research communications, 446(2), 590-595 (2014-03-19)
Trichloroethylene (TCE), a major occupational and environmental pollutant, has been recently associated with aberrant epigenetic changes in experimental animals and cultured cells. TCE is known to cause severe hepatotoxicity; however, the association between epigenetic alterations and TCE-induced hepatotoxicity are not
Cheryl Siegel Scott et al.
Environmental health perspectives, 114(9), 1471-1478 (2006-09-13)
A large body of epidemiologic evidence exists for exploring causal associations between cancer and trichloroethylene (TCE) exposure. The U.S. Environmental Protection Agency 2001 draft TCE health risk assessment concluded that epidemiologic studies, on the whole, support associations between TCE exposure
Hong Sik Yoo et al.
Journal of toxicology and environmental health. Part A, 78(1), 15-31 (2014-11-27)
Trichloroethylene (TCE) is a widely used organic solvent. Although TCE is classified as carcinogenic to humans, substantial gaps remain in our understanding of interindividual variability in TCE metabolism and toxicity, especially in the liver. A hypothesis was tested that amounts
Roy M Irving et al.
Toxicology, 306, 157-161 (2013-02-19)
The nephrotoxicity and nephrocarcinogenicity of trichloroethylene (TCE) and tetrachloroethylene (PCE) are believed to be mediated primarily through the cysteine S-conjugate β-lyase-dependent bioactivation of the corresponding cysteine S-conjugate metabolites S-(1,2-dichlorovinyl)-l-cysteine (DCVC) and S-(1,2,2-trichlorovinyl)-l-cysteine (TCVC), respectively. DCVC and TCVC have previously been
Hideaki Watanabe et al.
Dermatology (Basel, Switzerland), 221(1), 17-22 (2010-04-22)
Patients having a generalised rash with severe liver dysfunction associated with exposure to trichloroethylene (TCE) have been reported mainly in Asian countries. However, no case has been reported in Japan since the 1990s. Here, we describe a case of hypersensitivity
Sedat Abusoglu et al.
Archives of environmental & occupational health, 69(3), 180-186 (2013-12-12)
The aim of this study was to determine 8-hydroxydeoxyguanosine (8-OH-dG) levels in trichloroethylene (TCE)-exposed workers. Oxidative stress biomarkers and biochemical parameters were monitored among 26 TCE-exposed workers and 78 age-matched control subjects. Levels of urinary 8-OH-dG were analyzed by liquid
Prabhakar Pant et al.
Journal of environmental sciences (China), 22(1), 116-126 (2010-04-20)
Research works in the recent past have revealed three major biodegradation processes leading to the degradation of trichloroethylene. Reductive dechlorination is an anaerobic process in which chlorinated ethenes are used as electron acceptors. On the other hand, cometabolism requires oxygen
Bryan A Bassig et al.
Environmental and molecular mutagenesis, 54(6), 450-454 (2013-06-26)
To evaluate the immunotoxicity of trichloroethylene (TCE), we conducted a cross-sectional molecular epidemiology study in China of workers exposed to TCE. We measured serum levels of IL-6, IL-10, and TNF-α, which play a critical role in regulating various components of
Martin Bommer et al.
Science (New York, N.Y.), 346(6208), 455-458 (2014-10-04)
Organohalide-respiring microorganisms can use a variety of persistent pollutants, including trichloroethene (TCE), as terminal electron acceptors. The final two-electron transfer step in organohalide respiration is catalyzed by reductive dehalogenases. Here we report the x-ray crystal structure of PceA, an archetypal
Jacob Bælum et al.
Water research, 47(7), 2467-2478 (2013-03-16)
We used current knowledge of cellular processes involved in reductive dechlorination to develop a conceptual model to describe the regulatory system of dechlorination at the cell level; the model links bacterial growth and substrate consumption to the abundance of messenger
Fariha Zaheer et al.
Neurologic clinics, 29(3), 657-665 (2011-08-02)
Multiple genetic and environmental etiologies have been implicated in the pathogenesis of idiopathic Parkinson disease. Recent observations have suggested an association between chronic exposure to trichloroethylene (TCE) and development of clinical parkinsonism. Animal models of TCE exposure have shown nigrostriatal
Michihiro Kamijima et al.
International archives of occupational and environmental health, 80(5), 357-370 (2006-11-16)
Workers exposed to trichloroethylene (TCE) rarely show severe generalized skin disorders and accompanying hepatitis which resemble drug hypersensitivities. The disorders are completely different from solvent-induced irritating contact dermatitis, and their serious consequences have become one of the critical occupational health
Sarah J Blossom et al.
Toxicology and applied pharmacology, 269(3), 263-269 (2013-04-10)
Previous studies demonstrated that low-level postnatal and early life exposure to the environmental contaminant, trichloroethylene (TCE), in the drinking water of MRL+/+ mice altered glutathione redox homeostasis and increased biomarkers of oxidative stress indicating a more oxidized state. Plasma metabolites
Jelle Vlaanderen et al.
Occupational and environmental medicine, 70(6), 393-401 (2013-03-01)
Trichloroethylene (TCE) and Perchloroethylene (PER) are two chlorinated solvents that are applied widely as degreasers of metal parts, and in dry cleaning and other applications. In 2012, the International Agency for Research on Cancer classified TCE as carcinogenic to humans
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