266-257-8

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Allosteric communication between the pyridoxal 5'-phosphate (PLP) and heme sites in the H2S generator human cystathionine β-synthase.

Pramod Kumar Yadav et al.

The Journal of biological chemistry, 287(45), 37611-37620 (2012-09-15)

Human cystathionine β-synthase (CBS) is a unique pyridoxal 5'-phosphate (PLP)-dependent enzyme that has a regulatory heme cofactor. Previous studies have demonstrated the importance of Arg-266, a residue at the heme pocket end of α-helix 8, for communication between the heme

Chemical evidence for the existence of activated G-actin.

W P Shu et al.

The Biochemical journal, 283 ( Pt 2), 567-573 (1992-04-15)

Globular actin (G-actin) will polymerize to form filamentous actin (F-actin) under physiological ionic conditions, and is known to be regulated by univalent and bivalent cations, such as K+ and Mg2+. The current concept of this process involves four steps: activation

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