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关键词:'319112'
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Mindy R Rabinowitz et al.
The Laryngoscope, 124(11), 2531-2536 (2014-06-14)
Sentinel lymph node biopsy (SLNB) has been utilized for cutaneous melanoma and other malignancies arising from the eye and ocular adnexa. Currently, SLNB requires blue dyes and/or radiopharmaceuticals; both of which have significant shortcomings. This study sought to evaluate the
Fabio Stellari et al.
Journal of translational medicine, 13, 251-251 (2015-08-05)
Chronic inflammation of the airways is a central component in lung diseases and is frequently associated with bacterial infections. Monitoring the pro-inflammatory capability of bacterial virulence factors in vivo is challenging and usually requires invasive methods. Lung inflammation was induced
Yongyuan Guo et al.
International journal of nanomedicine, 10, 4593-4603 (2015-08-01)
Surface topography has significant influence on good and fast osseointegration of biomedical implants. In this work, ultrasonic shot peening was conducted to modify titanium to produce nanograined (NG) surface. Its ability to induce new bone formation was evaluated using an
M A Jarzabek et al.
British journal of cancer, 111(12), 2275-2286 (2014-11-07)
Glioblastoma (GBM), being a highly vascularised and locally invasive tumour, is an attractive target for anti-angiogenic and anti-invasive therapies. The GBM/endothelial cell response to gossypol/temozolomide (TMZ) treatment was investigated with a particular aim to assess treatment effects on cancer hallmarks.
Paulo Freire et al.
Inflammatory bowel diseases, 20(11), 2038-2045 (2014-09-05)
Ulcerative colitis (UC) is associated with an increased risk of colorectal cancer. Chromoendoscopy showed superiority to conventional colonoscopy (CC) in surveillance studies including high-risk patients. We aimed to compare chromoendoscopy-guided endomicroscopy (CGE) with CC for intraepithelial neoplasia (IN) detection in
Hong-zhi Pan et al.
Journal of biotechnology, 214, 133-138 (2015-09-22)
We describe the fabrication of a sensitive electrochemical DNA biosensor for determination of Klebsiella pneumoniae carbapenemase (KPC). The highly sensitive and selective electrochemical biosensor for DNA detection was constructed based on a glassy carbon electrode (GCE) modified with gold nanoparticles
Maria Samalidou et al.
Experimental biology and medicine (Maywood, N.J.), 240(12), 1728-1734 (2015-06-17)
Liposomal amphotericin B, voriconazole, and caspofungin are currently used for systemic and severe fungal infections. Patients with malignant diseases are treated with granulocyte-colony stimulating factor (G-CSF) for the recovery of granulocytes after chemotherapy or hematopoietic cell (HC) transplantation. Since they
Ting Wen Chung et al.
Asian Pacific journal of cancer prevention : APJCP, 15(18), 7995-8001 (2014-10-09)
Interferon-gamma (IFN-γ) has been used to treat various malignant tumors. However, the molecular mechanisms underlying the direct anti-proliferative activity of IFN-γ are poorly understood. In the present study, we examined the in vitro antitumor activity of IFN-γ on two human
H Sehaqui et al.
Soft matter, 11(26), 5294-5300 (2015-06-09)
Waste pulp residues are herein exploited for the synthesis of a sorbent for humic acid (HA), which is a major water pollutant. Cellulose pulp was etherified with a quaternary ammonium salt in water thereby introducing positive charges onto the surface
Valentina Di Felice et al.
Journal of tissue engineering and regenerative medicine, 9(11), E51-E64 (2013-04-18)
The use of three-dimensional (3D) cultures may induce cardiac progenitor cells to synthesize their own extracellular matrix (ECM) and sarcomeric proteins to initiate cardiac differentiation. 3D cultures grown on synthetic scaffolds may favour the implantation and survival of stem cells
Chunlei Tang et al.
Scientific reports, 5, 11241-11241 (2015-06-11)
Adenine nucleotide translocase (ANT) is a constitutive mitochondrial component that is involved in ADP/ATP exchange and mitochondrion-mediated apoptosis in yeast and mammals. However, little is known about the function of ANT in pathogenic fungi. In this study, we identified an
Anant Narayan Bhatt et al.
BMC cancer, 15, 335-335 (2015-05-01)
Cancer cells exhibit increased glycolysis for ATP production (the Warburg effect) and macromolecular biosynthesis; it is also linked with therapeutic resistance that is generally associated with compromised respiratory metabolism. Molecular mechanisms underlying radio-resistance linked to elevated glycolysis remain incompletely understood.
Leonardo Guasti et al.
The Journal of clinical endocrinology and metabolism, 99(11), E2198-E2206 (2014-08-20)
The hormone fibroblast growth factor 21 (FGF21) is a key metabolic regulator in the adaptation to fasting. In food-restricted mice, inhibition of skeletal growth is mediated by the antagonistic effect of FGF21 on GH action in the liver and growth
Onion membrane: an efficient adsorbent for decoloring of wastewater.
Saber-Samandari S and Heydaripour J
Journal of environmental health science & engineering (2015)
Kunihiko Nishino et al.
Antimicrobial agents and chemotherapy, 53(8), 3541-3543 (2009-06-10)
Screening of Salmonella mutants for the ability to increase beta-lactam resistance has led to the identification of a mutation in hns, which codes for the histone-like nucleoid structuring protein (H-NS). In this study, we report that H-NS modulates multidrug resistance
Jessica Y Rathbun et al.
Journal of virology, 89(16), 8428-8443 (2015-06-05)
Certain members of the Arenaviridae family are category A agents capable of causing severe hemorrhagic fevers in humans. Specific antiviral treatments do not exist, and the only commonly used drug, ribavirin, has limited efficacy and can cause severe side effects.
Rosyana V Albuquerque et al.
PloS one, 10(8), e0134768-e0134768 (2015-08-19)
Dapsone (DDS) hydroxylamine metabolites cause oxidative stress- linked adverse effects in patients, such as methemoglobin formation and DNA damage. This study evaluated the ameliorating effect of the antioxidant resveratrol (RSV) on DDS hydroxylamine (DDS-NHOH) mediated toxicity in vitro using human
Subir Kumar Nandy et al.
AMB Express, 4, 38-38 (2014-06-21)
Determination of metabolically active cell count is an important step in designing, operating and controlling fermentation processes. It's particularly relevant in processes involving mixed cultures, where multiple species contribute to the total growth. The motivation for the current study is
Reena Sharma et al.
Journal of environmental management, 162, 37-45 (2015-07-29)
Conducting hydrogels possessing antibacterial activity were developed using a two-step free-radical aqueous polymerization method to incorporate polyaniline chains into an adsorbent Guar gum/acrylic acid hydrogel network. The material properties of the synthesized samples were characterized using FTIR spectroscopy, thermal analysis
Brian D Dalm et al.
Pain, 156(12), 2562-2571 (2015-11-20)
Patients with neuropathic pain commonly present with spontaneous pain, in addition to allodynia and hyperalgesia. Although evoked responses in neuropathic pain models are well characterized, determining the presence of spontaneous pain is more challenging. We determined whether the chronic constriction
Yolanda Corbett et al.
Microbes and infection, 17(3), 184-194 (2014-12-03)
In malaria, the evidence concerning the nucleotide-binding, oligomerization domain (NOD) 2 (NOD2) receptor is fragmented and the stimuli that might activate NOD2 are not well characterized. We investigated the role of NOD2 in vitro in the response of macrophages to Plasmodium
Microscopic structural alterations
and p53 immune-expression in adult
rat testis in response to intra-tunical versus
intra-parenchymal injection of methylene blue
and p53 immune-expression in adult
rat testis in response to intra-tunical versus
intra-parenchymal injection of methylene blue
Mazroa S A
International Journal of Clinical and Experimental Pathology, 9, 5346-5356 (2016)
Vishwan Pamarthi et al.
Journal of vascular and interventional radiology : JVIR, 25(9), 1398-1404 (2014-05-20)
To review the indications, technical approach, and clinical outcomes of thoracic duct embolization (TDE) and thoracic duct disruption (TDD) in patients with symptomatic chylous effusions. A total of 105 patients who underwent 120 consecutive TDE/TDD procedures were retrospectively reviewed. Data
Bridget K Mutuma et al.
Journal of colloid and interface science, 442, 1-7 (2014-12-17)
TiO2 photocatalysts with a mixture of different TiO2 crystal polymorphs have customarily been synthesized hydrothermally at high temperatures using complicated and expensive equipment. In this study TiO2 nanoparticles with a mixture of TiO2 crystals were synthesized using a modified sol-gel
Swati Singh et al.
The Analyst, 139(14), 3600-3606 (2014-05-31)
The first gold-mercaptopropionic acid-polyethylenimine composite based electrochemical DNA biosensor was fabricated for the early detection of Streptococcus pyogenes infection in humans causing rheumatic heart disease (heart valve damage). No biosensor is available for the detection of rheumatic heart disease (RHD).
Tanmay M Shekhar et al.
Mutation research, 777, 23-32 (2015-04-29)
Chemotherapy and radiotherapy can cause permanent damage to the genomes of surviving cells, provoking severe side effects such as second malignancies in some cancer survivors. Drugs that mimic the activity of death ligands, or antagonise pro-survival proteins of the Bcl-2
Feng-Jen Tseng et al.
BMC systems biology, 8, 57-57 (2014-06-03)
During osteoclastogenesis, the maturation of osteoclast (OC) progenitors is stimulated by the receptor activator of nuclear factor-κB ligand (RANKL). Excess OC production plays a critical role in the pathogenesis of inflammatory bone disorders. Conversely, the inhibition of abnormal OC proliferation
Paulo Freire et al.
Scandinavian journal of gastroenterology, 49(10), 1219-1229 (2014-08-27)
Ulcerative colitis (UC) is associated with an increased risk of colorectal cancer (CRC). Aberrant crypt foci (ACF) are important biomarkers of sporadic CRC risk. Their correlation with the risk of intraepithelial neoplasia (IN) in UC remains unclear. To assess whether
Tamer Al Kayal et al.
PloS one, 10(4), e0125110-e0125110 (2015-04-22)
Demineralized bone matrix (DBM) is widely used for bone regeneration. Since DBM is prepared in powder form its handling properties are not optimal and limit the clinical use of this material. Various synthetic and biological carriers have been used to
Yuanyuan Zhang et al.
Analytica chimica acta, 882, 27-31 (2015-06-05)
Serum level of disease markers may provide important guidance for diagnosis and prognosis. In this work, a sensitive and specific method suitable for direct serum detection of biomarkers is developed based on peptide nucleic acid (PNA)-coupled DNA cycling reactions with
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