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显示 1-30 共 44 条结果 关于 "330-12-1" 范围 论文
Marci L Chew et al.
Clinical drug investigation, 35(5), 299-305 (2015-03-27)
The controlled-release (CR) formulation of pregabalin is designed to remain in the stomach for a prolonged period while slowly releasing pregabalin for absorption in the small intestine. This study evaluated the effect of the gastrointestinal prokinetic agent, erythromycin, on the
S Bannwarth et al.
The Journal of biological chemistry, 276(52), 48803-48813 (2001-10-20)
TRBP1 and TRBP2 are isoforms of a double-stranded RNA-binding protein that differ in their N-terminal end and were each identified by binding to human immunodeficiency virus type 1 (HIV-1) trans-activation-responsive RNA. TRBP1 and TRBP2 also bind and modulate the function
Giuseppe Stabile et al.
Journal of cardiovascular electrophysiology, 31(7), 1694-1701 (2020-05-06)
Ablation index (AI) is a new lesion quality marker that has been demonstrated to allow a high single-procedure arrhythmia-free survival in single-center studies. This prospective, multi-center study was designed to evaluate the reproducibility of pulmonary vein (PV) isolation guided by
Hiroko Tsujii et al.
European journal of medicinal chemistry, 45(6), 2191-2197 (2010-02-16)
3alpha-methoxyserrat-14-en-21beta-ol (1) and 3beta-methoxyserrat-14-en-21beta-ol (2) and their conjugates with curcumin, kojic acid, quercetin, and baicalein (3-18), as well as new analogs (19-24) derived from 1 and 2, were tested for their inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation
Xiang Cheng et al.
Biochemical and biophysical research communications, 419(3), 578-583 (2012-03-03)
Natural resistance-associated macrophage protein 1 (NRAMP1) containing 548 amino acids (AA) and 12 transmembrane domains (TMDs) is localized in membranes of lysosomes. Our study aimed to investigate the targeting motifs of NRAMP1 by expressing GFP-tagged full-length and truncated NRAMP1 proteins
R M McCormack et al.
Genes and immunity, 3(7), 433-435 (2002-11-09)
A recent study employing Australian and UK type 1 diabetes families has demonstrated significant transmission bias to affected offspring of a polymorphism (1188A allele; termed allele 1) in the 3' untranslated region (3'UTR) of the interleukin 12B (IL12B) gene which
V S Ivanova et al.
Human genetics, 94(3), 303-306 (1994-09-01)
The human histone H2A.X gene is unusual in that its transcripts are alternatively processed to yield two species, one a 0.6-kb replication-linked histone mRNA and the other a 1.6-kb polyadenylated mRNA. The H2A.X gene has been localized by fluorescence in
R Shamsadin et al.
Cytogenetics and cell genetics, 92(1-2), 134-138 (2001-04-18)
The mammalian 5'-AMP-activated protein kinase (AMPK) is a heterotrimeric protein consisting of alpha-, beta- and gamma-subunits. The alpha-subunit is the catalytic subunit. The non-catalytic subunits AMPK-beta and AMPK-gamma form, together with the catalytic AMPK-alpha, the active kinase complex in mammals
C L Welch et al.
Journal of lipid research, 37(7), 1406-1421 (1996-07-01)
As part of an effort to dissect the genetic factors involved in cholesterol homeostasis in the mouse model, we report the mapping of 12 new candidate genes using linkage analysis. The genes include: cytoplasmic HMG-CoA synthase (Hmgcs 1, Chr 13)
Fangyuan Lin et al.
Mikrochimica acta, 187(1), 66-66 (2019-12-20)
Manganese(II)-doped zinc sulfide nanocrystals (Mn:ZnS NCs) with dual-emission fluorescence (peaks at 445 nm and 590 nm under 330 nm excitation), good water stability and low toxicity were synthesized by hot injection. The fluorescence intensity of both emission bands of the nanocrystals can change
Kun-Hua Lu et al.
Mikrochimica acta, 186(4), 227-227 (2019-03-09)
Water-soluble nitrogen-doped carbon quantum dots (C-dots) were fabricated by microwave-induced decomposition of the precursor materials citric acid and N,N'-bis(2-aminoethyl)-1,2-ethanediamine. The C-dots were placed on portable paper strips with novel origami designs to simplified user operations. The intensity of the blue
Nicoletta Potenza et al.
Nucleic acids research, 34(10), 2906-2913 (2006-06-02)
Human ribonuclease-1 (hRNase-1) is an extracellular enzyme found in exocrine pancreas, blood, milk, saliva, urine and seminal plasma, which has been implicated in digestion of dietary RNA and in antiviral host defense. The enzyme is characterized by a high catalytic
Ann Chen Wu et al.
American journal of respiratory and critical care medicine, 186(6), 508-513 (2012-07-17)
Low vitamin D levels are associated with asthma and decreased airway responsiveness. Treatment with inhaled corticosteroids improves airway responsiveness and asthma control. To assess the effect of vitamin D levels on prebronchodilator FEV(1), bronchodilator response, and responsiveness to methacholine (PC(20)
Peter Friedrich et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(50), 16114-16122 (2012-10-20)
Coenzyme B(12) can assist radical enzymes that accomplish the vicinal interchange of a hydrogen atom with a functional group. It has been proposed that the Co-C bond homolysis of coenzyme B(12) to cob(II)alamin and the 5'-deoxyadenosyl radical is aided by hydrogen bonding
M Nishi et al.
Molecular endocrinology (Baltimore, Md.), 3(11), 1775-1781 (1989-11-01)
The gene-encoding human islet amyloid polypeptide (hIAPP), a recently discovered 37 amino acid hormone-like polypeptide which is expressed in the insulin-producing beta-cells of the endocrine pancreas, has been isolated and characterized. The coding region of the gene is interrupted in
Cindy Karouta et al.
Investigative ophthalmology & visual science, 56(1), 299-309 (2014-12-11)
In chicks, daily exposure to bright light (15,000 lux) retards the development of form-deprivation myopia (FDM) by roughly 60%. This study investigated whether higher light intensities increase the amount of protection against FDM, and whether protection and light intensity are
M Uboldi Uboldi de Capei et al.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics, 30(1), 5-10 (2003-02-01)
It has been demonstrated that many cytokine genes [e.g. tumour necrosis factor alpha (TNF-alpha) and interleukin 10 (IL-10)] show polymorphisms which may affect gene transcription, causing individual variations in cytokine production. The majority of polymorphisms described are single nucleotide polymorphisms
F B Essien et al.
The Journal of nutrition, 123(1), 27-34 (1993-01-01)
The Axd (axial defects) mutation, which causes open neural tube defects (NTD) in 25-30% of d 14 mouse embryos of heterozygous (Axd/+) matings and curly tails (CT) in 31%, can be useful in studying neurovertebral morphogenesis. Current interest focuses on
Gisèle El Dib et al.
The journal of physical chemistry. A, 117(1), 117-125 (2012-12-06)
The reaction of the OH radicals with 4-hydroxy-2-butanone was investigated in the gas phase using an absolute rate method at room temperature and over the pressure range 10-330 Torr in He and air as diluent gases. The rate coefficients were
Susan M Wernimont et al.
The Journal of nutrition, 142(7), 1272-1279 (2012-06-01)
Genes functioning in folate-mediated 1-carbon metabolism are hypothesized to play a role in cardiovascular disease (CVD) risk beyond the current narrow focus on the MTHFR 677 C→T (rs1801133) polymorphism. Using a cohort study design, we investigated whether sequence variants in
Martin J Bek et al.
Hypertension (Dallas, Tex. : 1979), 47(2), 288-295 (2005-12-29)
Dopamine receptors are important in systemic blood pressure regulation. D4 receptors are expressed in the kidney and brain, but their role in cardiovascular regulation is unknown. In pentobarbital-anesthetized mice, systolic and diastolic blood pressures were elevated in sixth-generation D4 receptor-deficient
Maria Helena Weber et al.
Journal of physiology and biochemistry, 68(3), 365-375 (2012-02-02)
Heat shock protein 70 (HSP70) is a chaperone that maintains protein conformation during heat stress. It has recently been observed that HSP70 may be released from cells in response to increased energy demand (e.g., exercise) and/or oxidative stress. Since HSP70
Y K Jung et al.
Molecular endocrinology (Baltimore, Md.), 5(9), 1257-1268 (1991-09-01)
Several genomic clones encoding carboxypeptidase-E (CPE) have been isolated and partially sequenced. Southern blot analysis indicates that a single copy of this gene is present in the rat genome. The entire gene spans approximately 50 kilobases and consists of nine
Tumaini V Mhada et al.
BMC public health, 12, 904-904 (2012-10-26)
Neonatal sepsis contributes significantly to morbidity and mortality among young infants. The aetiological agents as well as their susceptibility to antimicrobial agents are dynamic. This study determined aetiology, antimicrobial susceptibility and clinical outcome of neonatal sepsis at Muhimbili National Hospital.
Marina Verena Hoffmann et al.
BMC veterinary research, 8, 206-206 (2012-11-01)
In this methodology article a thermal threshold testing device designed to test nociception in cats was assessed in six dogs. The purpose of this study was to investigate baseline reproducibility of thermal thresholds obtained by the contact heat testing device
A J Soitamo et al.
The Journal of biological chemistry, 276(23), 19699-19705 (2001-03-30)
The mammalian hypoxia-inducible factor-1 (HIF-1) is a heterodimeric transcription factor that controls the induction of several genes involved in glycolysis, erythropoiesis, and angiogenesis when cells are exposed to hypoxic conditions. Until now, the expression and function of HIF-1alpha have not
K Rajender Reddy et al.
The Lancet. Infectious diseases, 15(1), 27-35 (2014-12-09)
We did a phase 3 study in previous non-responders with chronic hepatitis C virus (HCV) genotype 1 infection and compensated liver disease that related to the standard of care for these patients at the time this study was initiated. We
Bjorn Nashan et al.
Trials, 16, 118-118 (2015-04-16)
Introduction of calcineurin inhibitors had led to improved survival rates in liver transplant recipients. However, long-term use of calcineurin inhibitors is associated with a higher risk of chronic renal failure, neurotoxicity, de novo malignancies, recurrence of hepatitis C viral (HCV)
Silvia Cristina de Sousa Paredes et al.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 16(7), 844-851 (2020-04-27)
A paucity of information is available on the comparative nutritional deficiencies considering the presence of metabolic syndrome (MetS) and nutritional changes after vertical sleeve gastrectomy (SG). To compare the nutritional status in patients with and without MetS before and 1
Tingting Zhang et al.
Analytical and bioanalytical chemistry, 407(21), 6543-6555 (2015-06-24)
This article describes the development of a lipidomic platform consisting of a 4000 QTRAP mass spectrometer and a self-installed sample inlet system to indentify and quantify 12 phospholipid and five sphingolipid classes from lipid-rich brain tissues of mouse, duck, and
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