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Yongsheng Ye et al.
Cardiovascular and interventional radiology, 42(8), 1183-1191 (2019-05-03)
To evaluate the level of artery occlusion, degradation periods, tissue response and vessel recanalization of calibrated gelatin sponge particles after segmental renal artery embolization. Superselective embolization of 14 adult rabbits was performed with calibrated gelatin sponge particles (150-350 μm). Two rabbits
Morgayn I Read et al.
American journal of physiology. Heart and circulatory physiology, 309(9), H1554-H1564 (2015-09-06)
Seizures are associated with altered autonomic activity, which has been implicated in the development of cardiac dysfunction and structural damage. This study aimed to investigate the involvement of the autonomic nervous system in seizure-induced cardiomyopathy. Male Sprague-Dawley rats (320-350 g)
Y K Li et al.
Poultry science, 71(1), 151-160 (1992-01-01)
Chicken fibroblast cells isolated from 7-day-old White Leghorn S-line chicken embryos were used for microcell hybridization. Cells transfected with a pSV2-neo plasmid, which carries the Neor gene and confers resistance to geneticin (G418), were selected and maintained in medium containing
M Maegele et al.
Physiological research, 64(1), 129-145 (2014-09-07)
To determine whether the exposure to long term enriched environment (EE) would result in a continuous improvement of neurological recovery and ameliorate the loss of brain tissue after traumatic brain injury (TBI) vs. standard housing (SH). Male Sprague-Dawley rats (300-350
Luís Belo et al.
PloS one, 9(6), e98467-e98467 (2014-06-06)
Bilirubin has potential antioxidant and anti-inflammatory properties. The UGT1A1*28 polymorphism (TA repeats in the promoter region) is a major determinant of bilirubin levels and recent evidence suggests that raised adiposity may also be a contributing factor. We aimed to study
C F Polo et al.
Comparative biochemistry and physiology. B, Comparative biochemistry, 103(1), 251-256 (1992-09-01)
1. Heme regulation before the appearance of hyperplastic nodules was investigated in mice models of hepatocarcinogenesis. 2. With this aim 5-aminolaevulinate synthetase (ALA-S), microsomal heme-oxygenase (MHO), mitochondrial and cytoplasmic rhodanese activities were examined throughout a period of 35 days in
I A Wasfi et al.
American journal of veterinary research, 58(6), 636-640 (1997-06-01)
To document disposition variables of phenylbutazone and its metabolite, oxyphenbutazone, in camels (Camelus dromedarius) after single i.v. bolus administration of phenylbutazone, with a view to making recommendation on avoiding violative residues in racing camels. 6 healthy camels (4 males, 2
Rachel M Lestz et al.
Pediatric nephrology (Berlin, Germany), 29(10), 2021-2028 (2014-05-06)
Higher doses of erythropoiesis-stimulating agents (ESA) have been associated with an increased risk of adverse outcomes in adults with chronic kidney disease (CKD) and end-stage kidney disease (ESRD), but to our knowledge no trials have been performed in children. We
Thomas A Rasmussen et al.
The lancet. HIV, 5(5), e221-e230 (2018-04-13)
Whether ongoing virus replication occurs in HIV-infected individuals on antiretroviral therapy (ART) is unclear; therefore, whether residual virus replication is a barrier to achieving a cure for HIV is also unknown. We aimed to establish whether ART intensification with dolutegravir
Mikhail Linetsky et al.
Investigative ophthalmology & visual science, 44(9), 3920-3926 (2003-08-27)
To determine the mechanism that leads to the UVA light-dependent loss of glutathione reductase (GR) activity in human lens (HL). Both the HL water-soluble (WS) fraction and yeast GR were irradiated with UVA light (200 mW/(cm(2). h) for 1 hour
K Datta et al.
Toxicology, 125(1), 1-11 (1998-05-19)
2,6-Dithiopurine (DTP) has been proposed as a possible chemopreventive agent because of its ability to react with electrophiles. Acrolein, an electrophilic metabolite of cyclophosphamide (CP) involved in the toxicities of this anticancer drug, can be scavenged by DTP. The present
M Pestana et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 16 Suppl 1, 53-59 (2001-05-23)
The present report addresses the status of the renal dopaminergic system activity in patients afflicted with different renal disorders and in the remnant kidney of uninephrectomized (UNX) rats, based on the urinary excretion of L-DOPA, dopamine and amine metabolites. In
P Robberecht et al.
Molecular pharmacology, 42(2), 347-355 (1992-08-01)
In AR 4-2J rat pancreatic acinar cell membranes, receptors for the two pituitary adenylate cyclase-activating peptides (PACAP) PACAP-27 (the short version of PACAP) and PACAP-38 [the long version, with a carboxyl-terminal (residues 28-38) extension] can be subdivided into (a) type
Gary Middleton et al.
The Lancet. Oncology, 15(8), 829-840 (2014-06-24)
We aimed to assess the efficacy and safety of sequential or simultaneous telomerase vaccination (GV1001) in combination with chemotherapy in patients with locally advanced or metastatic pancreatic cancer. TeloVac was a three-group, open-label, randomised phase 3 trial. We recruited patients
Jiří Grim et al.
Clinical pharmacokinetics, 54(5), 503-515 (2014-12-17)
This study estimated patients' early response following neoadjuvant chemoradiotherapy (CHRT) of locally advanced rectal cancer based on 5-fluorouracil (5-FU). The target was to achieve pathological complete response (pCR; residual disease-free stage) and toxicities of grade ≤2, using individual dosing predicted
E A Ott et al.
Journal of animal science, 77(11), 3022-3030 (1999-11-24)
Thoroughbred and Quarter Horse yearlings (n = 24; 335+/-7 d of age) were used in a 112-d feeding trial to determine whether chromium (Cr) supplementation would alter growth, development, and energy metabolism of growing horses on high-concentrate diets. The horses
Husna Ismail et al.
BMC infectious diseases, 20(1), 621-621 (2020-08-25)
We aimed to describe an outbreak of cutaneous abscesses caused by Panton-Valentine leukocidin (PVL)-producing methicillin-susceptible Staphylococcus aureus (MSSA) among gold mine workers. In February 2018, we retrospectively reviewed a random sample of 50 medical records from 243 cases and conducted
N Steele et al.
New Zealand veterinary journal, 62(1), 38-46 (2013-09-24)
To evaluate the efficacy of nil, three or six treatments of penethamate hydriodide on successive days for treatment of subclinical mastitis on the bacteriological cure proportion and subsequent somatic cell count (SCC). Milk samples were collected from all glands of
Claudia A Seelig et al.
Clinical laboratory, 66(5) (2020-05-12)
Autoantibodies against the chromosome associated protein DFS70/LEDGF (dense fine speckled 70/ lens epithelial growth factor; anti-DSF70) are increasingly being regarded as biomarkers for the diagnostic exclusion of systemic autoimmune rheumatic diseases (SARD). In routine ANA screening by indirect immunofluores-cence (IIFT)
John Frater et al.
The lancet. HIV, 8(8), e474-e485 (2021-06-22)
Data on vaccine immunogenicity against SARS-CoV-2 are needed for the 40 million people globally living with HIV who might have less functional immunity and more associated comorbidities than the general population. We aimed to explore safety and immunogenicity of the
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