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Exploring the potential of xanthene derivatives as trypanothione reductase inhibitors and chloroquine potentiating agents.
Chibale K, et al
Tetrahedron, 59(13), 2289-2296 (2003)
G Angelini et al.
Contact dermatitis, 32(2), 96-99 (1995-02-01)
In the past year, 1200 consecutive eczematous patients were tested with cocamidopropylbetaine 1% aq. Contact allergy was evinced in 46 subjects (3.8%), while irritant reactions (slight erythema only) were observed in 15 cases (1.25%). 30 out of 46 patients with
G Angelini et al.
Contact dermatitis, 34(4), 248-252 (1996-04-01)
Since finding that all subjects with contact allergy to cocamidopropylbetaine give positive reactions to 3-dimethylaminopropylamine (DMPA), we wished to verify whether sensitization to other industrially-used tensioactives might also be due to content of DMPA as an impurity. We also investigated
New antihistaminic agents: Synthesis and evaluation of h 1-antihistaminic actions of 3-[(N,N-dialkylamino) alkyl)-1, 2, 3, 4-tetrahydro-(1H)-thioquinazolin-4 (3H)-ones and their oxo analogues.
Raju MB, et al
Indian Journal of Pharmaceutical Sciences, 69(6), 853-853 (2007)
Lin-Feng Li
Contact dermatitis, 58(1), 24-27 (2007-12-25)
The prevalence of sensitization to cocamidopropyl betaine (CAPB) in China has not been reported. This study is to evaluate the prevalence of CAPB sensitization in patients patch tested in Peking University Third Hospital, Beijing. 429 consecutive patients with suspected allergic
Clare Ho et al.
Journal of chromatography. A, 1235, 103-114 (2012-03-20)
Morantel, pyrantel and their drug-related metabolites in food of animal-origin are regulated as sum of residues which may be hydrolysed to N-methyl-1,3-propanediamine (NMPA). In this study, an isotope dilution liquid chromatography tandem mass spectrometry (LC-MS/MS) method with pentafluoropropionic acid anhydride
DNA complexation by cationic pullulan possessing thermo-sensitive units.
Constantin M, et al.
Digest Journal of Nanomaterials and Biostructures, 6, 849-861 (2011)
Occupational allergic contact dermatitis from 3-dimethylaminopropylamine in shampoos.
L Kanerva et al.
Contact dermatitis, 35(2), 122-123 (1996-08-01)
Dhananjay Jere et al.
Biomedical materials (Bristol, England), 4(2), 025020-025020 (2009-04-08)
Bioreducible disulfide linkage-employing drug conjugate has already been approved for drug delivery application, and also has shown immense potential in gene and siRNA transfection. This paper will focus on the recent developments in bioreducible polymeric systems for gene and siRNA
Heparin-substituted nylon tubing as a model for the study of lipoprotein interactions and metabolism.
A J Redfern et al.
Biochemical Society transactions, 22(3), 308S-308S (1994-08-01)
P. Lappe et al.
Chem. Zeit., 111, 117-117 (1987)
Permanently antimicrobial waterborne coatings based on the dual role of modified poly (styrene-co-maleic anhydride).
Cloete WJ, et al
Eur. Polymer J., 49(5), 1080-1088 (2013)
Linda Moreau et al.
Dermatitis : contact, atopic, occupational, drug, 15(3), 146-149 (2005-02-24)
We present the case of a patient with facial dermatitis caused by sensitization to cocamidopropyl betaine. The patient also had positive patch-test reactions to cocamidoamine, 3-(dimethylamino)propylamine, and oleamidopropyl dimethylamine. The presence of 3-(dimethylamino)propylamine as an impurity in all of these
The Rebirth of Waste Cooking Oil to Novel Bio-based Surfactants.
Zhang QQ, et al.
Scientific Reports, 5 (2015)
Marcos Hervella et al.
Actas dermo-sifiliograficas, 97(3), 189-195 (2006-06-27)
It has been discovered that all individuals who are allergic to cocamidopropyl betaine (CAPB) are sensitized to 3-dimethylaminopropylamine (DMAPA) and to amidoamine, molecules which are intermediaries in CAPB synthesis, and which persist as impurities in the material that is sold;
Iwona Kowalczyk
Molecules (Basel, Switzerland), 13(2), 379-390 (2008-02-29)
1,1-Dimethyl-3-oxo-1,4-diazepan-1-ium chloride (1) and 1,1-dimethyl-1-carboxymethyl-3-aminopropyl ammonium hydrochloride (2) have been obtained by the reactions of 1,1-dimethyl-1,3-propylenediamine with ethyl chloroacetate and chloroacetic acid, respectively. The products have been characterized by FTIR, Raman and NMR spectroscopy. B3LYP calculations have also been carried
Liya Ge et al.
Talanta, 81(4-5), 1861-1864 (2010-05-06)
As the first attempt, ionic liquid solutions have been employed for direct extraction of proteins from yeast cells. Compared with effects of 21 different ionic liquid solutions on the extraction efficiency, 3-(dimethylamino)-1-propylaminium formate ([DMAPA]FA) was selected as the suitable ionic
Sofie Meng Andersen et al.
Organic letters, 17(4), 944-947 (2015-02-04)
Inexpensive 3-(dimethylamino)-1-propylamine (DMAPA) was found to be effective in anomeric deacylation reactions giving 1-O deprotected sugars in high yield as precursors for the formation of imidate glycosyl donors. DMAPA was also found to be useful for removing excess reagents such
Allergy to cocamidopropyl betaine may be due to amidoamine: a patch test and product use test study.
J F Fowler et al.
Contact dermatitis, 37(6), 276-281 (1998-02-10)
Cocamidopropyl betaine (CAPB) is an amphoteric surfactant commonly used in personal care products and surface cleaners. Patch testing with commercially-available CAPB has yielded occasional reactions indicative of allergic contact dermatitis. To determine if subjects with previous positive patch tests would
Ga Young Park et al.
Journal of the American Chemical Society, 134(20), 8513-8524 (2012-05-11)
Certain side-on peroxo-dicopper(II) species with particularly low ν(O-O) (710-730 cm(-1)) have been found in equilibrium with their bis-μ-oxo-dicopper(III) isomer. An issue is whether such side-on peroxo bridges are further activated for O-O cleavage. In a previous study (Liang, H.-C., et
A Comprehensive Mechanism for Aromatic Nucleophilic Substitution in Aprotic Solvents: Derivation of the Whole Reaction Scheme for Third Order in Amine Kinetic Law.
Alvaro CE, et al.
Physical Chemistry, 3(2), 39-47 (2013)
Carrier and inhibitory effects of surfactants on allergic contact reactions to 3-dimethylaminopropylamine.
G Angelini et al.
Contact dermatitis, 39(3), 152-153 (1998-10-15)
Eleanor Knopp et al.
Dermatitis : contact, atopic, occupational, drug, 19(6), 328-333 (2009-01-13)
We present the case of a 42-year-old woman with intractable eyelid dermatitis. Patch testing revealed sensitization to 3-(dimethylamino)propylamine (DMAPA). DMAPA is an important etiology of allergic contact dermatitis of the eyelids and face but is easily missed even with expanded-series
Peter Ulrich et al.
The American journal of tropical medicine and hygiene, 91(4), 824-832 (2014-09-04)
Because of emerging resistance to existing drugs, new chemical classes of antimalarial drugs are urgently needed. We have rationally designed a library of compounds that were predicted to accumulate in the digestive vacuole and then decrystallize hemozoin by breaking the
K M Vasquez et al.
The Journal of biological chemistry, 276(42), 38536-38541 (2001-08-16)
Triplex-forming oligonucleotides (TFOs) bind specifically to duplex DNA and provide a strategy for site-directed modification of genomic DNA. Recently we demonstrated TFO-mediated targeted gene knockout following systemic administration in animals. However, a limitation to this approach is the requirement for
Lack of patch test reactivity to 3-dimethylaminopropylamine in German hairdressers.
W Uter
Contact dermatitis, 41(4), 231-231 (1999-10-09)
J P McFadden et al.
Contact dermatitis, 45(2), 72-74 (2001-09-13)
7 patients allergic to cocamidopropyl betaine (CAPB) were detected by positive patch test reactions to Tegobetaine L7TM. These patients were then asked to participate in further testing to its potential impurities, cocamidopropylamine and 3-dimethylaminopropylamine (DMAPA). 4 of the 7 patients
E C Nickle et al.
Biochimica et biophysica acta, 704(2), 345-352 (1982-06-04)
Escherichia coli asparaginase (L-asparagine amidohydrolase, EC 3.5.1.1) has been modified by succinylation, acetylation and the attachment of N,N-dimethyl-1,3-propanediamine and glucuronic acid. The effect of these modifications on plasma clearance rates in mice and on other properties is compared to the
Novel pH-sensitive zwitterionic poly(amino acid) derivatives for drug delivery.
Xiaojuan Wang et al.
Journal of controlled release : official journal of the Controlled Release Society, 152 Suppl 1, e93-e94 (2011-12-27)
Occupational allergic contact dermatitis due to 3-dimethylaminopropylamine.
E L Speight et al.
Contact dermatitis, 28(1), 49-50 (1993-01-01)
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