406-10-0

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Inhibition of glycosaminoglycan synthesis and protein glycosylation with WAS-406 and azaserine result in reduced islet amyloid formation in vitro.

Rebecca L Hull et al.

American journal of physiology. Cell physiology, 293(5), C1586-C1593 (2007-09-07)

Deposition of islet amyloid polypeptide (IAPP) as amyloid in the pancreatic islet occurs in approximately 90% of individuals with Type 2 diabetes and is associated with decreased islet beta-cell mass and function. Human IAPP (hIAPP), but not rodent IAPP, is

Differential fluctuation in virulence and VOC profiles among different cultures of entomopathogenic fungi.

Abid Hussain et al.

Journal of invertebrate pathology, 104(3), 166-171 (2010-03-18)

Insect-passaged cultures of entomopathogenic fungi grown on potato dextrose agar media have been shown to have altered virulence and profiles of volatile compounds. The present study demonstrated the pathogenic status of FS(0) (in vitro) and FS(1) and FS(2) (insect-passaged cultures

RNA-binding protein LIN28 is a marker for primary extragonadal germ cell tumors: an immunohistochemical study of 131 cases.

Dengfeng Cao et al.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(2), 288-296 (2010-11-09)

LIN28 has been shown to have an important role in primordial germ cell development and malignant transformation of germ cells in mouse. In this study, we examined the immunohistochemical profile of LIN28 in 131 primary human extragonadal germ cell tumors

RNA-binding protein LIN28 is a marker for primary extragonadal germ cell tumors: an immunohistochemical study of 131 cases.

Dengfeng Cao et al.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(2), 288-296 (2010-11-09)

Gossypol disrupts embryo development in heifers.

M Villaseñor et al.

Journal of dairy science, 91(8), 3015-3024 (2008-07-25)

Our objectives were to determine the effects of dietary free gossypol (FG) intake on plasma and uterine gossypol concentrations and embryo development and viability before and after culture with gossypol. Fifty postpubertal Holstein heifers weighing (+/-SD) 406 +/- 34.5 kg

Efficacy and safety of loteprednol etabonate 0.5% gel in the treatment of ocular inflammation and pain after cataract surgery.

Rajesh K Rajpal et al.

Journal of cataract and refractive surgery, 39(2), 158-167 (2012-12-12)

To examine the efficacy and safety of a new gel formulation loteprednol etabonate 0.5% in the treatment of inflammation and pain after cataract surgery. Seventeen United States clinical sites. Prospective double-masked parallel-group study. Patients with anterior chamber cell (ACC) grade

Characterization of raft microdomains in bovine mammary tissue during lactation: How they are modulated by fatty acid treatments.

H Taga et al.

Journal of dairy science, 104(2), 2384-2395 (2020-11-29)

The objective of the current study was first to characterize lipid raft microdomains isolated as detergent-resistant membranes (DRM) from mammary gland tissue, and second to determine how dietary fatty acids (FA) such as conjugated linoleic acid (CLA), 19:1 cyclo, and

NIV Is not Adequate for High Intensity Endurance Exercise in COPD.

Tristan Bonnevie et al.

Journal of clinical medicine, 9(4) (2020-04-12)

Noninvasive ventilation (NIV) during exercise has been suggested to sustain higher training intensity but the type of NIV interface, patient-ventilator asynchronies (PVA) or technological limitation of the ventilator may interfere with exercise. We assessed whether these parameters affect endurance exercise

A regulatory polymorphism at position -309 in PTPRCAP is associated with susceptibility to diffuse-type gastric cancer and gene expression.

Hyoungseok Ju et al.

Neoplasia (New York, N.Y.), 11(12), 1340-1347 (2009-12-19)

PTPRCAP (CD45-AP) is a positive regulator of protein tyrosine phosphatase PTPRC (CD45), which activates Src family kinases implicated in tumorigenesis. Single-nucleotide polymorphism (SNP) rs869736 located at position -309 of the PTPRCAP promoter was associated with susceptibility to diffuse-type gastric cancer

Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene.

T Hansen et al.

Diabetes, 47(4), 598-605 (1998-05-06)

The high-affinity sulfonylurea receptor (SUR1) is, as a subunit of the ATP-sensitive potassium channel, an important regulator of insulin secretion in the pancreatic beta-cell. The aim of this study was to examine if genetic variability of the SUR1 gene was

Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants.

Arne Ohlsson et al.

The Cochrane database of systematic reviews, 2, CD003481-CD003481 (2020-02-12)

Indomethacin is used as standard therapy to close a patent ductus arteriosus (PDA) but is associated with reduced blood flow to several organs. Ibuprofen, another cyclo-oxygenase inhibitor, may be as effective as indomethacin with fewer adverse effects. To determine the

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