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Chia-Wen Kuo et al.
Life sciences, 135, 77-86 (2015-05-27)
Diabetic nephropathy is the leading cause of end stage renal disease in developed countries throughout the world. The imbalance between the production of reactive oxygen species (ROS) and the antioxidant defense system is the main problem that is responsible for
Diethyl pyrocarbonate in nucleic acid research.
L Ehrenberg et al.
Progress in nucleic acid research and molecular biology, 16, 189-262 (1976-01-01)
Kelly Yoshizaki et al.
Respiratory research, 16, 18-18 (2015-04-08)
Diesel exhaust particles (DEPs) are deposited into the respiratory tract and are thought to be a risk factor for the development of diseases of the respiratory system. In healthy individuals, the timing and mechanisms of respiratory tract injuries caused by
Sana Sungur et al.
Food additives & contaminants. Part B, Surveillance, 8(3), 190-194 (2015-04-22)
The determination of phthalates in edible oils (virgin olive oil, olive oil, canola oil, hazelnut oil, sunflower oil, corn oil) sold in Turkish markets was carried out using gas chromatography-mass spectrometry. Mean phthalate concentrations were between 0.102 and 3.863 mg
Sheridan K Haack et al.
Applied and environmental microbiology, 81(10), 3430-3441 (2015-03-15)
Manure spills into streams are relatively frequent, but no studies have characterized stream contamination with zoonotic and veterinary pathogens, or fecal chemicals, following a spill. We tested stream water and sediment over 25 days and downstream for 7.6 km for
Ning Wu et al.
Marine drugs, 13(10), 6210-6225 (2015-10-06)
Chitosan and its derivatives such as low molecular weight chitosans (LMWCs) have been reported to exert many biological activities, such as antioxidant and antitumor effects. However, complex and molecular weight dependent effects of chitosan remain controversial and the mechanisms that
Yingying Wang et al.
Bioresource technology, 102(22), 10173-10179 (2011-10-01)
This study was reported on a novel process for fatty acid ethyl esters preparation by transesterification and esterification from renewable low-cost feedstock camellia oil soapstocks and friendly acyl acceptor diethyl carbonate. The main components of product were 83.9% ethyl oleate
Xin Zhao et al.
Molecular medicine reports, 12(2), 3191-3199 (2015-05-09)
In the present study, the therapeutic effects of Lactobacillus casei Qian (LC-Qian), the key microorganism in Tibetan yak yoghurt, on activated carbon-induced constipation were determined in vivo. ICR mice were treated with LC-Qian for nine days by oral administration. The
Srabani Karmakar et al.
The protein journal, 31(7), 623-640 (2012-08-15)
α-Crystallin, a member of the small heat shock protein family is the major protein of mammalian eye lens and is a molecular chaperone. As there is no protein turn over in the lens, stability of α-crystallin is one of the
S Moisset et al.
Environmental science and pollution research international, 22(6), 4046-4055 (2014-09-17)
This study examined the effects of diuron on strains of three major freshwater diatom species, Eolimna minima, Nitzschia palea and Planothidium lanceolatum. These species are frequently recorded in the Morcille River, where diuron runs off during phytosanitary treatments of the
Qi Miao et al.
Drug metabolism and pharmacokinetics, 26(5), 494-502 (2011-06-30)
The aim of this study was to investigate the pharmacokinetic mechanism of interaction between JBP485 and zinc. The plasma concentration of JBP485 after oral administration in vivo, the plasma concentration of JBP485 from the portal vein after jejunal perfusions in
Zaigham Abbas Rizvi et al.
Toxicology in vitro : an international journal published in association with BIBRA, 29(6), 1275-1282 (2014-12-03)
Effect of poly-dispersed acid-functionalized single-walled carbon nanotubes (AF-SWCNTs) was examined on lipid antigen presentation through CD1d pathway on three cell lines, LA4, MHS, and JAWSII used as prototype antigen presenting cells (APCs). CD1d molecule was expressed on 80-90% MHS (prototype
Chen-Hsu Wang et al.
Pharmaceutical biology, 52(11), 1451-1459 (2014-07-16)
Abstract Background: Carbamazepine, which was developed primarily for the treatment of epilepsy, is now also useful for the treatment of non-epileptic disorders and inflammatory hyperalgesia. However, the mechanism of its anti-neuroinflammatory action remains poorly understood. This study elucidates the anti-neuroinflammatory
Simona Portaro et al.
Neuromolecular medicine, 17(3), 285-296 (2015-05-27)
Myotonia congenita (MC) is an inherited muscle disease characterized by impaired muscle relaxation after contraction, resulting in muscle stiffness. Both recessive (Becker's disease) or dominant (Thomsen's disease) MC are caused by mutations in the CLCN1 gene encoding the voltage-dependent chloride
Michaela Frybortova et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 19(7), 1203-1208 (2014-07-06)
Oligonucleotides modified by clinically ineffective trans-diamminedichloridoplatinum(II) (transplatin) have been shown to be effective modulators of gene expression. This is so because in some nucleotide sequences the 1,3-GNG intrastrand adducts formed by transplatin in double-helical DNA readily rearrange into interstrand cross-links
Hao Xu et al.
Stem cells and development, 24(22), 2723-2732 (2015-07-15)
Excitatory commissural V3 interneurons (INs) of the ventral spinal cord have been shown to balance locomotor rhythm regularity and robustness in vivo. Unfortunately, due to the scarcity of these cells in the spinal cord, in vitro studies of dissociated V3
Xiaowei Liu et al.
Environmental science and pollution research international, 22(14), 10690-10698 (2015-03-11)
The first nationwide survey of six phthalates (diethyl phthalate (DEP); dimethyl phthalate (DMP); di-n-butyl phthalate (DBP); butyl benzyl phthalate (BBP); bis(2-ethylhexyl) phthalate (DEHP); din-octyl phthalate (DnOP)) in drinking waters from waterworks was conducted across seven geographical zones in China. Of
Milo B Fasken et al.
PLoS genetics, 11(3), e1005044-e1005044 (2015-03-17)
Non-coding RNAs (ncRNAs) play critical roles in gene regulation. In eukaryotic cells, ncRNAs are processed and/or degraded by the nuclear exosome, a ribonuclease complex containing catalytic subunits Dis3 and Rrp6. The TRAMP (Trf4/5-Air1/2-Mtr4 polyadenylation) complex is a critical exosome cofactor
Santino Orecchio et al.
Journal of toxicology and environmental health. Part A, 78(15), 1008-1018 (2015-08-12)
A simple and fast method is proposed to analyze commercial personal perfumes. Our method includes measurement of phthalates, known to be major sources of endocrine disruptor chemicals (EDC), which originate from the less volatile fraction of perfumes. The quantification of
Liyan Jiang et al.
Clinical laboratory, 61(8), 1009-1015 (2015-10-03)
Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism, hyperinsulinemia, and infertility. In PCOS, abnormal regulation of relevant genes is required for follicular development. By binding to the 3' untranslated region (3'URT), microRNAs (miRNAs) are widely involved in posttranscriptional gene regulation.
Yuan Zhang et al.
PloS one, 10(9), e0137998-e0137998 (2015-09-12)
The Wangyang River (WYR) basin is a typical wastewater irrigation area in Hebei Province, North China. This study investigated the concentration and distribution of six priority phthalate esters (PAEs) in the agricultural soils in this area. Thirty-nine soil samples (0-20
Jonathan L Hess et al.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 168B(1), 14-35 (2014-12-20)
Advances in molecular genetics, fueled by the results of large-scale genome-wide association studies, meta-analyses, and mega-analyses, have provided the means of identifying genetic risk factors for human disease, thereby enriching our understanding of the functionality of the genome in the
Mariella Caputo et al.
Electromagnetic biology and medicine, 33(4), 289-295 (2013-08-28)
We evaluated the effects, on cultured human SaOS-2 cells, of exposures to the low frequency (LF) electric signal (60 kHz sinusoidal wave, 24.5 V peak-to-peak voltage, amplitude modulated by a 12.5 Hz square wave, 50% duty cycle) from an apparatus of current clinical
Xiaomei Liu et al.
Journal of chromatography. A, 1409, 46-52 (2015-08-01)
In this study, the magnetic Zeolitic Imidazolate Framework-8 (ZIF-8) microspheres were successfully synthesized and applied as an effective sorbent for preconcentration of several typical phthalate esters (PAEs) from environmental water samples. Firstly, the solvothermal treatment method was used for preparation
A new method based on the use of diethyl pyrocarbonate as a nuclease inhibitor for the extraction of undegraded nucleic acid from plant tissues.
F Solymosy et al.
European journal of biochemistry, 5(4), 520-527 (1968-09-24)
Diana A T Nijholt et al.
Journal of Alzheimer's disease : JAD, 46(1), 227-238 (2015-03-05)
Increased levels of pregnancy zone protein (PZP) were found in the serum of persons who later developed Alzheimer's disease (AD) in comparison to controls who remained dementia free. We suggested that this increase is due to brain derived PZP entering
Marina Pierdominici et al.
Particle and fibre toxicology, 11, 74-74 (2014-12-17)
Diesel exhaust particles (DEP) are major constituents of ambient air pollution and their adverse health effect is an area of intensive investigations. With respect to the immune system, DEP have attracted significant research attention as a factor that could influence
Lívia Neves Borgheti-Cardoso et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 74, 103-117 (2015-04-29)
The development of delivery systems able to complex and release siRNA into the cytosol is essential for therapeutic use of siRNA. Among the delivery systems, local delivery has advantages over systemic administration. In this study, we developed and characterized non-viral
Yan Li et al.
Biosensors & bioelectronics, 67, 364-369 (2014-09-10)
The development of sensitive telomerase biosensors is hindered by the restricted accessibility of telomere strand (TS) primer and the limited enzyme reaction space, which is mainly confined by the vertical distance. In this work, we designed an electrochemical telomerase biosensor
Edie I Crosse et al.
Cell stem cell, 27(5), 822-839 (2020-09-19)
Hematopoietic stem cells (HSCs) first emerge in the embryonic aorta-gonad-mesonephros (AGM) region. Studies of model organisms defined intersecting signaling pathways that converge to promote HSC emergence predominantly in the ventral domain of the dorsal aorta. Much less is known about
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