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42088
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Elin Engdahl et al.
International journal of molecular sciences, 22(11) (2021-06-03)
The breast cancer resistance protein (BCRP) is an important efflux transporter in the blood-brain barrier (BBB), protecting the brain from a wide range of substances. In this study, we investigated if BCRP function is affected by bisphenol A (BPA), a
Ravindranath Reddy Gilibili et al.
Toxicological sciences : an official journal of the Society of Toxicology, 140(1), 26-39 (2014-04-23)
There is a growing body of evidence that exposure to endocrine disrupting chemicals and to estrogenic compounds in particular can affect the testis and male fertility. In the present study, the constitutive expression of steroidogenic and non-steroidogenic cytochrome P450 (CYP)
Sanghyuk Bae et al.
Hypertension (Dallas, Tex. : 1979), 65(2), 313-319 (2014-12-10)
Bisphenol A (BPA) is a chemical used in plastic bottles and inner coating of beverage cans, and its exposure is almost ubiquitous. BPA has been associated with hypertension and decreased heart rate variability in the previous studies. The aim of
Teng Zhang et al.
Environmental and molecular mutagenesis, 55(4), 343-353 (2014-01-25)
Bisphenol-A (BPA) and diethylhexyl phthalate (DEHP) are estrogenic compounds widely used in commercial plastic products. Previous studies have shown that exposure to such compounds have adverse effects on various aspects of mammalian reproduction including folliculogenesis. The objective of this study
Wei Wang et al.
Toxicology and applied pharmacology, 276(2), 157-164 (2014-03-01)
Bisphenol A (BPA) is a known reproductive toxicant in rodents. However, the effects of in utero BPA exposure on early ovarian development and the consequences of such exposure on female reproduction in later reproductive life are unclear. Thus, we determined
Rajesh Kumar et al.
Journal of chromatography. A, 1359, 16-25 (2014-08-02)
A simple, fast and sensitive analytical method using fabric phase sorptive extraction (FPSE) followed by high performance liquid chromatography with fluorescence detection (HPLC-FLD) has been developed for efficient quantification of biologically important molecules e.g., 17α-ethynylestradiol (EE2), β-estradiol (E2) and bisphenol
L K Dodgen et al.
Environmental pollution (Barking, Essex : 1987), 193, 29-36 (2014-07-06)
Pharmaceutical and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs) enter the soil environment via irrigation with treated wastewater, groundwater recharge, and land application of biosolids. The transformation and fate of PPCP/EDCs in soil affects their potential for plant
Maoyong Song et al.
Chemosphere, 112, 275-281 (2014-07-23)
Halogenated bisphenol A (H-BPAs), widely used in industrial production, have been identified in various environmental matrices and detected in human serum and breast milk. The persistence and prevalence of H-BPAs in the environment underscore the need to in-depth understand their
Maria Gloria Luciani-Torres et al.
Carcinogenesis, 36(1), 168-176 (2014-11-21)
Identification of early perturbations induced in cells from non-cancerous breast tissue is critical for understanding possible breast cancer risk from chemical exposure. We have demonstrated previously that exposure to the ubiquitous xenoestrogens, bisphenol A (BPA) and methyl paraben, promotes the
Raja Rezg et al.
Environment international, 64, 83-90 (2014-01-03)
Bisphenol-A (BPA) is one of the highest volume chemicals produced worldwide, with over 6billion pounds produced and over 100t released into the atmosphere each year. Recent extensive literature has raised concerns about its possible implication in the etiology of some
Marco Pellegrini et al.
Journal of cellular physiology, 229(8), 1061-1068 (2013-12-19)
Sex steroid hormones differently control the major physiological processes in male and female organisms. In particular, their effects on vascular smooth muscle cells (VSMCs) migration are at the root of sex/gender-related differences reported in the cardiovascular system. Several exogenous substances
Xin Xu et al.
Molecular carcinogenesis, 54(2), 134-147 (2013-09-07)
Rat mammary carcinoma susceptibility 5a1 (Mcs5a1), which is concordant to human MCS5A1 breast cancer risk locus, mediates susceptibility by a non-mammary cell-autonomous mechanism associated with T cell differential expression of F-box protein 10 (Fbxo10). Human FBXO10, an evolutionarily conserved ubiquitin
Ruth B Lathi et al.
Fertility and sterility, 102(1), 123-128 (2014-04-22)
To examine the relationship between the maternal serum bisphenol A (BPA) concentration at the time of the missed menstrual cycle and miscarriage risk. Retrospective cohort of prospectively collected serum samples. Academic fertility center. Women presenting for early pregnancy monitoring with
Toxicology: The plastics puzzle.
Josie Glausiusz
Nature, 508(7496), 306-308 (2014-04-18)
Brendan J Holland et al.
Analytica chimica acta, 842, 35-41 (2014-08-17)
Sodium polyphosphate is commonly used to enhance chemiluminescence reactions with acidic potassium permanganate through a dual enhancement mechanism, but commercially available polyphosphates vary greatly in composition. We have examined the influence of polyphosphate composition and concentration on both the dual
Priyadarshini Mirmira et al.
Translational research : the journal of laboratory and clinical medicine, 164(1), 13-21 (2014-04-02)
Bisphenol A (BPA) is a ubiquitous industrial chemical found in a variety of plastic containers intended for food storage and in the epoxy resin linings of metal food and beverage cans, where it is used to prevent corrosion, food contamination
James A Rogers et al.
Molecular immunology, 53(4), 421-430 (2012-11-06)
Endocrine disrupting chemicals (EDCs) have become of concern for a variety f health issues. Due to their effects on the endocrine system they have been thoroughly examined with regards to sexual dysfunction, malformation, and cancers of reproductive origin. Bisphenol-A (BPA)
Ying Jiang et al.
Toxicology letters, 228(2), 85-92 (2014-04-29)
An emerging literature suggests that bisphenol A (BPA), a widespread endocrine disrupting chemical, when exposure occurs in early life, may increase the risk of metabolic syndrome. In this study, we investigated the hypothesis that perinatal exposure to BPA predisposed offspring
Xiaoli Wang et al.
The Journal of endocrinology, 221(2), 201-213 (2014-02-18)
Bisphenol-A (BPA), an environmental estrogen, adversely affects female reproductive health. However, the underlying mechanisms remain largely unknown. We found that oral administration (p.o.) of BPA (20 μg/kg) to adult female mice at proestrus, but not at estrus or diestrus, significantly
Francesca Maradonna et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 166, 1-13 (2014-07-02)
Previous studies in rats have indicated that a diet enriched with Bisphenol A adversely effects metabolism and reproductive success. In rats exposed to BPA by maternal gavage, alteration in the developmental programming, higher obesity rates and reproductive anomalies were induced.
Jacob R LaBauve et al.
General dentistry, 60(5), 424-432 (2012-10-04)
Bisphenol A (BPA) is a common industrial chemical that has been associated with a variety of biological disorders. From the unborn to the elderly, BPA affects every demographic of the population; however, its potential long-term effects on prenatal and prepubescent
Arunoday Bhan et al.
The Journal of steroid biochemistry and molecular biology, 141, 160-170 (2014-02-19)
Antisense transcript, long non-coding RNA HOTAIR is a key player in gene silencing and breast cancer and is transcriptionally regulated by estradiol. Here, we have investigated if HOTAIR expression is misregulated by bisphenol-A (BPA) and diethylstilbestrol (DES). Our findings demonstrate
Tinne Geens et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(10), 3725-3740 (2012-08-15)
Due to the large number of applications of bisphenol-A (BPA), the human exposure routes are multiple. We aimed to review shortly the food and non-food sources of BPA, and to evaluate their contribution to the human exposure. Food sources discussed
News from the IADR.
F J Trevor Burke
Dental update, 41(6), 481-482 (2014-09-10)
Tye E Arbuckle et al.
Environment international, 68, 55-65 (2014-04-09)
Bisphenol A (BPA) and phthalates are endocrine disruptors possibly linked to adverse reproductive and neurodevelopmental outcomes. These chemicals have commonly been measured in urine in population surveys; however, such data are limited for large populations of pregnant women, especially for
Daniel N Weber et al.
Journal of toxicology and environmental health. Part A, 78(1), 50-66 (2014-11-27)
Developmental bisphenol A (BPA) exposure is associated with adverse behavioral effects, although underlying modes of action remain unclear. Because BPA is a suspected xenoestrogen, the objective was to identify sex-based changes in adult zebrafish social behavior developmentally exposed to BPA
Laura N Vandenberg et al.
Ciencia & saude coletiva, 17(2), 407-434 (2012-01-24)
Bisphenol A (BPA) is one of the highest-volume chemicals produced worldwide, and human exposure to BPA is thought to be ubiquitous. Thus, there are concerns that the amount of BPA to which humans are exposed may cause adverse health effects.
A Iparraguirre et al.
Journal of chromatography. A, 1356, 163-170 (2014-07-09)
Membrane-assisted solvent extraction (MASE) coupled to liquid chromatography-triple quadrupole mass spectrometry (LC-MS/MS) was studied for the determination of a variety of emerging and priority compounds in wastewater. Among the target analytes studied certain hormones (estrone (E1), 17β-estradiol (E2), androsterone (ADT)
Lucas J Brand et al.
Oncotarget, 6(6), 3811-3824 (2015-02-12)
The androgen receptor (AR) is a driver of prostate cancer (PCa) cell growth and disease progression. Therapies for advanced PCa exploit AR dependence by blocking the production or action of androgens, but these interventions inevitably fail via multiple mechanisms including
R Rodríguez-Gómez et al.
Journal of chromatography. A, 1349, 69-79 (2014-05-28)
In the present work, two specific, accurate and sensitive methods for the determination of endocrine disrupting chemicals (EDCs) in human breast milk are developed and validated. Bisphenol A and its main chlorinated derivatives, five benzophenone-UV filters and four parabens were
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