CN
Search Within
448869
应用筛选条件
关键词:'448869'
显示 1-30 共 207 条结果 关于 "448869" 范围 论文
Manli Zhong et al.
Frontiers in aging neuroscience, 13, 660249-660249 (2021-05-04)
Alzheimer's disease (AD) is a type of neurodegenerative disease that is associated with the accumulation of amyloid plaques. Increasing non-amyloidogenic processing and/or manipulating amyloid precursor protein signaling could reduce AD amyloid pathology and cognitive impairment. D-penicillamine (D-Pen) is a water-soluble
I-Mo Fang et al.
Experimental eye research, 130, 38-50 (2014-12-06)
The purpose of the present study was to investigate the protective effect and mechanism of chitosan oligonucleotides (COS) on retinal ischemia and reperfusion (I/R) injury. Rats pretreated with PBS, low-dose COS (5 mg/kg), or high-dose COS (10 mg/kg) were subjected to retinal
Dae-Sung Lee et al.
Food chemistry, 148, 97-104 (2013-11-23)
In this study, the antioxidant and antimicrobial activities of chitosan-caffeic acid, chitosan-ferulic acid, and chitosan-sinapic acid conjugates with different grafting ratios were investigated. The synthesized chitosan-hydroxycinnamic acid conjugates were verified by performing (1)H NMR and differential scanning calorimetry analysis. The
Neslihan Beyazit et al.
Carbohydrate polymers, 240, 116333-116333 (2020-06-02)
In this work, two new chitosan-Schiff base derivatives (HCS-GSP and LCS-GSP) were synthesized by the condensation reaction of high molecular weight chitosan (HCS) and low molecular weight chitosan (LCS) with (-)-gossypol (GSP), respectively. For this purpose, racemic gossypol was isolated
Prabhu Prabhakara et al.
Pakistan journal of pharmaceutical sciences, 26(4), 779-786 (2013-07-03)
Site-specific delivery of anticancer based therapy of human cancers has led to several remarkable outcomes, particularly in the therapy of breast cancer and lymphoma. Camptothecin, a plant secondary metabolite is widely used in the treatment of metastatic breast cancer and
Shoko Shinya et al.
The Journal of biological chemistry, 288(42), 30042-30053 (2013-08-30)
Two carbohydrate binding modules (DD1 and DD2) belonging to CBM32 are located at the C terminus of a chitosanase from Paenibacillus sp. IK-5. We produced three proteins, DD1, DD2, and tandem DD1/DD2 (DD1+DD2), and characterized their binding ability. Transition temperature
Jeannine M Refos et al.
Antimicrobial agents and chemotherapy, 62(1) (2017-11-01)
Host chitinases, chitotriosidase and acidic mammalian chitinase (AMCase), improved the antifungal activity of caspofungin (CAS) against Aspergillus fumigatus in vitro These chitinases are not constitutively expressed in the lung. Here, we investigated whether chitosan derivatives were able to induce chitinase
Antonio Castro Marín et al.
Food chemistry, 285, 67-76 (2019-02-25)
The efficacy against oxidative degradation in model and sulphite-free white wines of two commercial, insoluble chitosans (one being approved for winemaking) were investigated by electron paramagnetic resonance (EPR). Both compounds at various doses significantly inhibited the formation of α-(4-pyridyl-1-oxide)-N-t-butylnitrone (4-POBN)-1-hydroxyethyl
Valeriya V Kardumyan et al.
Polymers, 13(7) (2021-04-04)
In this work, we studied the photocatalytic activity of photosensitizers (PSs) of various natures solubilized with polyvinylpyrrolidone (PVP) and ternary block copolymer ethylene and propylene oxide Pluronic F127 (F127) in a model reaction of tryptophan photo-oxidation in water in the
Christos Christou et al.
Carbohydrate polymers, 219, 298-305 (2019-06-04)
PVP/chitosan blended nanofibers have been prepared and investigated as adsorbent material for the removal of hexavalent uranium (U(VI)) from aqueous solutions. The nanofibers have been characterized prior and after U(VI) adsorption by SEM and FTIR measurements, and the effect of
Moacir Fernandes Queiroz et al.
Marine drugs, 13(1), 141-158 (2015-01-01)
Chitosan is widely used in the biomedical field due its chemical and pharmacological properties. However, intake of chitosan results in renal tissue accumulation of chitosan and promotes an increase in calcium excretion. On the other hand, the effect of chitosan
The Role of CHI3L1 (Chitinase-3-Like-1) in the Pathogenesis of Infections in Burns in a Mouse Model.
Stefan Bohr et al.
PloS one, 10(11), e0140440-e0140440 (2015-11-04)
In severe burn injury the unique setting of a depleted, dysfunctional immune system along with a loss of barrier function commonly results in opportunistic infections that eventually proof fatal. Unfortunately, the dynamic sequence of bacterial contamination, colonization and eventually septic
Gurpreet Kaur Khaira et al.
Journal of water and health, 11(3), 410-418 (2013-08-29)
The antibacterial activity of a water-soluble chitosan derivative prepared by chemical modification to quaternary ammonium compound N,N,N-trimethylchitosan (TC) was investigated against four selected waterborne pathogens: Aeromonas hydrophila ATCC 35654, Yersinia enterocolitica ATCC 9610, Listeria monocytogenes ATCC 19111 and Escherichia coli
Ajay Vijayakumar et al.
AAPS PharmSciTech, 18(3), 875-883 (2016-07-03)
The objective of this study was to formulate and characterize properties of solid lipid nanoparticle (SLN) dispersion containing quercetin. SLN was prepared by ultrasonication method using tripalmitin and lecithin as lipid core and then the surface was coated with chitosan.
A Shakila Banu et al.
IET nanobiotechnology, 7(1), 22-27 (2013-05-28)
Nanoenabled drug carriers are emerging as alternatives to conventional small-molecule drugs and their in-vitro biocompatibility evaluation with blood components is a necessary part of early preclinical development. In the present study, Chitosan-based bionanocomposites of sol-gel derived TiO2 and SiO2 were
Mariela Agotegaray et al.
Journal of nanoscience and nanotechnology, 14(5), 3343-3347 (2014-04-17)
New magnetic devices consisting of magnetite functionalized with oleic acid and chitosan have been synthesized and employed to the loading of Diclofenac as potential tool for treatment of targeted inflammatory diseases. Magnetic loaded and un-loaded nanoparticles have been thoroughly characterized
Matea Korica et al.
Materials (Basel, Switzerland), 14(13) (2021-07-20)
This research proposed two pretreatments of viscose fabrics: oxidation with 2,2,6,6-tetramethylpiperidine-1-oxy radical (TEMPO) and coating with TEMPO-oxidized cellulose nanofibrils (TOCN), to introduce functional groups (COOH and CHO) suitable for irreversible binding of chitosan nanoparticles without and with embedded zinc (NCS
Lana Glerieide Silva Garcia et al.
International journal of biological macromolecules, 143, 341-348 (2019-12-10)
Sporotrichosis, caused by Sporothrix schenckii complex species, is the most prevalent subcutaneous mycosis in many areas of Latin America. Chitosan has been used as an antifungal agent; however the effects of the molecular weight (MW) of chitosan (i.e. high (HMW)
Massimo Malerba et al.
International journal of molecular sciences, 16(2), 3019-3034 (2015-02-03)
Chitosan (CHT) is a non-toxic and inexpensive compound obtained by deacetylation of chitin, the main component of the exoskeleton of arthropods as well as of the cell walls of many fungi. In agriculture CHT is used to control numerous diseases
The Han Nguyen et al.
Journal of nanoscience and nanotechnology, 13(8), 5296-5304 (2013-07-26)
The physicochemical and biofunctional properties of crab chitosan nanoparticles of two different sizes (Nano A and B) manufactured by dry milling method were evaluated for commercialization. The deacetylation degrees (DD) of Nano A, B and the control chitosan were 90.9
Amritha Vijayan et al.
Scientific reports, 9(1), 19165-19165 (2019-12-18)
Application of growth factors at wound site has improved the efficiency and quality of healing. Basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) induce proliferation of various cells in wound healing. Delivery of growth factor from controlled
Lana Glerieide Silva Garcia et al.
Carbohydrate polymers, 195, 662-669 (2018-05-29)
Difficulties in the treatment of Candida spp. invasive infections are usually related to the formation of biofilms. The aim of this study was to determine the effects of molecular weight (MW) of chitosan (using high (HMW), medium (MMW) and low
Juan Pablo Loyola-Rodríguez et al.
Journal of applied biomaterials & functional materials, 17(3), 2280800019851771-2280800019851771 (2019-08-03)
The main microorganism associated with the failure of endodontic treatments is Enterococcus faecalis. Although several endodontic therapeutics have demonstrated antimicrobial activity against E. faecalis, the antimicrobial effectiveness of chitosan (CsNPs) and silver nanoparticles (AgNPs) included into conventional endodontic sealers for
Lili Zhang et al.
Journal of chromatography. A, 1365, 86-93 (2014-09-30)
Fourteen chitosan 3,6-diphenylcarbamate-2-urea derivatives were synthesized using well-deacetylated chitosan and the corresponding phenyl isocyanates. After coating them on silica gel, their chiral recognition abilities were evaluated as the chiral stationary phases (CSPs) for high-performance liquid chromatography. These coated-type CSPs exhibited
Bo Xiao et al.
Gastroenterology, 146(5), 1289-1300 (2014-02-08)
Nanoparticles have been explored as carriers of small interfering RNAs (siRNAs) and might be developed to treat patients with inflammatory bowel disease (IBD). Overexpression of CD98 on the surface of colonic epithelial cells and macrophages promotes the development and progression
Qianqian Lyu et al.
The Biochemical journal, 461(2), 335-345 (2014-04-29)
Chitosanase is able to specifically cleave β-1,4-glycosidic bond linkages in chitosan to produce a chito-oligomer product, which has found a variety of applications in many areas, including functional food and cancer therapy. Although several structures for chitosanase have been determined
Sandra Elisa Haas et al.
Pharmaceutical development and technology, 19(7), 769-778 (2013-09-04)
The aim of this study was to develop innovative nanosystems with isopropyl myristate as the oil core of self-assembly nanovesicles constituted of chitosan and lecithin using a 2(3) factorial design. The factors analyzed were chitosan (X1, levels 4 and 8
Mar Collado-González et al.
Marine drugs, 18(1) (2020-01-19)
Polyelectrolyte nanocomposites rarely reach a stable state and aggregation often occurs. Here, we report the synthesis of nanocomposites for the oral delivery of insulin composed of alginate, dextran sulfate, poly-(ethylene glycol) 4000, poloxamer 188, chitosan, and bovine serum albumin. The
Sara Gnavi et al.
International review of neurobiology, 109, 1-62 (2013-10-08)
Various biomaterials have been proposed to build up scaffolds for promoting neural repair. Among them, chitosan, a derivative of chitin, has been raising more and more interest among basic and clinical scientists. A number of studies with neuronal and glial
Pallab Datta et al.
Journal of biomedical nanotechnology, 9(5), 870-879 (2013-06-28)
Most polymeric nanofibers used for bone tissue engineering lack adequate functional groups for bioactivity. This study explores the potential of nanofibers of phosphate functionalized derivative of chitosan-N-methylene phosphonic chitosan (NMPC) for bone tissue engineering. Nanofibers were fabricated by electrospinning of
1/7