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The plant decapeptide OSIP108 prevents copper-induced toxicity in various models for Wilson disease.
Pieter Spincemaille et al.
Toxicology and applied pharmacology, 280(2), 345-351 (2014-08-20)
Wilson disease (WD) is caused by accumulation of excess copper (Cu) due to a mutation in the gene encoding the liver Cu transporter ATP7B, and is characterized by acute liver failure or cirrhosis and neuronal cell death. We investigated the
Yoshiaki Miyamoto et al.
Chemistry, an Asian journal, 8(4), 824-831 (2013-02-05)
The stereoselective direct transformation of N-(propargylic)hydroxylamines into cis-2-acylaziridines was achieved by the combined use of AgBF4 and CuCl. Copper salts were found to promote the transformation of the intermediary 4-isoxazolines into 2-acylaziridines and both 3-aryl- and 3-alkyl-substituted 2-acylaziridines could be
Sufeng Zhang et al.
Molecules (Basel, Switzerland), 25(1) (2020-01-08)
A facile approach was successfully developed for synthesis of cellulose nanocrystals (CNC)-supported magnetic CuFe2O4@Ag@ZIF-8 nanospheres which consist of a paramagnetic CuFe2O4@Ag core and porous ZIF-8 shell. The CuFe2O4 nanoparticles (NPs) were first prepared in the presence of CNC and dispersant.
I V Kushkevych et al.
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 83(6), 104-109 (2012-03-01)
Glutathione is the metal stress protector and changes of its level in the sulfate-reducing bacteria cells under the influence of heavy metal salts have not been studied yet. CdCl2, Pb(NO3)2, CuCl2, and ZnCl2 influence on the total glutathione level in
Su-Jeong Kim et al.
Free radical biology & medicine, 53(4), 936-950 (2012-06-12)
Loss-of-function mutations in the PARK7/DJ-1 gene cause early onset autosomal-recessive Parkinson disease. DJ-1 has been implicated in protection of neurons from oxidative stress and in regulation of transcriptional activity. However, whether there is a relationship between the subcellular localization of
Weiming Yuan et al.
Organic & biomolecular chemistry, 10(36), 7266-7268 (2012-08-09)
An efficient and practical copper-catalyzed highly regio- and stereoselective borylcupration of internal alkynes with bis(pinacolato)diboron using a catalytic amount of K(2)CO(3) as base producing Z-alkenylboron compounds has been demonstrated by applying the ligand effect: commercially available electron-rich tris(p-methoxyphenyl) phosphine ensures
Tingting Wang et al.
Journal of pharmaceutical sciences, 108(3), 1264-1271 (2018-11-13)
Poloxamer 188 (P188) is a triblock copolymer of the form polyethylene oxide-polypropylene oxide-polyethylene oxide (PEO-PPO-PEO). The center PPO block is hydrophobic, and the side PEO blocks are hydrophilic, resulting in surface-active properties. P188 has been used in the pharmaceutical industry
Mónica João Barros Amorim et al.
Environmental pollution (Barking, Essex : 1987), 164, 164-168 (2012-03-01)
Environmental effects of copper nanoparticles are little studied in terrestrial ecosystems. In the present article, the toxicity of copper nanoparticles (Cu-NP) on the enchytraeid Enchytraeus albidus is compared to the toxicity of a copper-salt (CuCl(2)). The effect parameters studied were
Kusaï Alomar et al.
Journal of inorganic biochemistry, 126, 76-83 (2013-06-25)
The reaction of nickel(II), copper(II) chlorides and cadmium(II) chloride and bromide with thiophene-2,3-dicarboxaldehyde bis(thiosemicarbazone) (2,3BTSTCH2) leads to a series of new complexes: [Ni(2,3BTSTCH)]Cl, [Cu(2,3BTSTC)], [CdCl2(2,3BTSTCH2)] and [CdBr2(2,3BTSTCH2)]. The crystal structures of the ligand and of [Ni(2,3BTSTCH)]Cl complex have been determined.
Mehmet Boğa et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 69(9-10), 381-390 (2015-02-26)
Two endemic Cirsium species, C. leucopsis DC. and C. sipyleum O. Schwarz, and C. eriophorum (L.) Scop. growing in Turkey were investigated to establish their secondary metabolites, fatty acid compositions, and antioxidant and anticholinesterase potentials. Spectroscopic methods were used to
Xiaojie Ding et al.
Luminescence : the journal of biological and chemical luminescence, 30(4), 465-471 (2014-09-30)
Cysteamine (CA)-capped CdTe quantum dots (QDs) (CA-CdTe QDs) were prepared by the reflux method and utilized as an efficient nano-sized fluorescent sensor to detect mercury (II) ions (Hg(2+) ). Under optimum conditions, the fluorescence quenching effect of CA-CdTe QDs was
Gloria Uccello-Barretta et al.
Journal of pharmaceutical and biomedical analysis, 107, 7-10 (2015-01-07)
In total parenteral nutrition (TPN), especially in the case of preterm infants, simultaneous administration of vitamins and trace elements is still a problematic issue: guidelines put in evidence the lack of specific documentation. In this work NMR spectroscopy was applied
Koharu Tambo et al.
Bioscience, biotechnology, and biochemistry, 77(2), 416-418 (2013-02-09)
Human amyloid-β peptide 1-42 (Aβ) was subjected to a radical reaction by using ascorbic acid and CuCl(2). The percentage of D-aspartic acid (D-Asp) after 24 h had increased to 6.69 ± 0.09%, this being comparable with the reported D-Asp concentration
Chunxia Qin et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(5), 812-817 (2014-03-15)
Human copper transporter 1 (CTR1) is overexpressed in a variety of cancers. This study aimed to evaluate the use of (64)CuCl2 as a theranostic agent for PET and radionuclide therapy of malignant melanoma. CTR1 expression levels were detected by Western
Thomas Beneyton et al.
The Analyst, 139(13), 3314-3323 (2014-04-16)
We present a high-throughput droplet-based microfluidic analysis/screening platform for directed evolution of CotA laccase: droplet-based microfluidic modules were combined to develop an efficient system that allows cell detection and sorting based on the enzymatic activity. This platform was run on
Landon John G Edgar et al.
Organic letters, 14(16), 4226-4229 (2012-08-01)
Glycosyl 1-phosphates enriched in the α-anomer are obtained without the use of protecting groups in two steps starting from the free hemiacetal. Condensation of free hemiacetals with toluenesulfonylhydrazide yields a range of glycosylsulfonohydrazide donors which can be oxidized using cupric
Krissada Surawathanawises et al.
The Analyst, 141(5), 1669-1677 (2016-02-24)
There is a need to develop inexpensive, portable and easy-to-use devices for viral sample processing for resource-limited settings. Here we offer a solution to efficient virus capture by incorporating macroporous materials with regular structures into microfluidic devices for affinity chromatography.
Antimicrobial Magnesium Hydroxide Nanoparticles As an Alternative to Cu Biocide for Crop Protection.
Ziyang Huang et al.
Journal of agricultural and food chemistry, 66(33), 8679-8686 (2018-07-22)
In agriculture, prolonged use of copper biocides increases the risk of development of Cu resistance and its accumulation in soil, demanding an alternative. In this paper, we report antimicrobial magnesium hydroxide nanoparticles (NPs) as an alternative to Cu biocides with
Lucélia Moraes-Silva et al.
Journal of biochemical and molecular toxicology, 26(9), 354-359 (2012-07-20)
This work investigated the effects of copper as preventive treatment against mercury-induced alterations in young rats. Wistar rats were treated (subcutaneous) with saline or CuCl(2) · 2H(2) O (6.9 mg/kg/day) from 3 to 7 days old and with saline or
Ying Yang et al.
Angewandte Chemie (International ed. in English), 53(45), 12142-12147 (2014-09-16)
Sugar moieties were incorporated into cross-linked polyurethane (PUR) networks in an effort to achieve self-repairing in the presence of atmospheric carbon dioxide (CO2) and water (H2O). When methyl-α-D-glucopyranoside (MGP) molecules are reacted with hexamethylene diisocyanate trimer (HDI) and polyethylene glycol
Huawei Cai et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(4), 622-628 (2014-03-19)
Copper is an element required for cell proliferation and angiogenesis. Human prostate cancer xenografts with increased (64)Cu radioactivity were visualized previously by PET using (64)CuCl2 as a radiotracer ((64)CuCl2 PET). This study aimed to determine whether the increased tumor (64)Cu
Julia Mazurków et al.
Sensors (Basel, Switzerland), 21(3) (2021-02-04)
The constant progress in novel nanomaterials synthesis has contributed to the rapid development of nonenzymatic glucose sensors. For working electrodes preparation, drop casting proved to be the most convenient and thus most widely applied method. However, appropriate interpretation of obtained
Kenji Funaki et al.
Organic letters, 14(24), 6186-6189 (2012-12-12)
Direct arylation of thiophenes and benzothiophenes with aryltrimethylsilanes was effectively catalyzed by PdCl(2)(MeCN)(2) in the presence of CuCl(2) as an oxidant. The reaction preferentially occurred at the β-position of both thiophenes and benzothiophenes.
Fuping Gao et al.
ACS nano, 9(5), 4976-4986 (2015-04-29)
Positron emission tomography (PET) imaging has received special attention owing to its higher sensitivity, temporal resolution, and unlimited tissue penetration. The development of tracers that target specific molecules is therefore essential for the development and utility of clinically relevant PET
Jing Xue et al.
PloS one, 9(10), e109180-e109180 (2014-10-02)
Chloroquine is an established antimalarial agent that has been recently tested in clinical trials for its anticancer activity. The favorable effect of chloroquine appears to be due to its ability to sensitize cancerous cells to chemotherapy, radiation therapy, and induce
Halil Gökce et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 96, 139-147 (2012-06-05)
In this study, the metal(II) halide of 2-(2'-thienyl)pyridine, (C(9)H(7)NS), (with synonym, 2-(2'-pyridyl)thiophene and 2-thiophen-2-ylpyridine), (in abbreviated pyth) have been formed by the reaction with copper chloride and was formulated as [Cu(pyth)(2)Cl(2)]. The structure and vibrational wavenumbers of the formed compound
Yoshiyuki Suzuki et al.
Radiology, 267(3), 941-947 (2013-02-19)
To develop a silicon (Si) and cadmium telluride (CdTe) imaging Compton camera for biomedical application on the basis of technologies used for astrophysical observation and to test its capacity to perform three-dimensional (3D) imaging. All animal experiments were performed according
Shuxia Zhou et al.
Pharmaceutical research, 30(5), 1311-1327 (2013-02-16)
Metal-catalyzed oxidation (MCO) of proteins is of primary concern in the development of biotherapeutics as it represents a prominent degradation pathway with potential undesired biological and biotherapeutic consequences. We developed a fluorogenic derivatization methodology to study the MCO of IgG1
Jing Tao et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(37), 9832-9837 (2017-09-01)
The optimal functionalities of materials often appear at phase transitions involving simultaneous changes in the electronic structure and the symmetry of the underlying lattice. It is experimentally challenging to disentangle which of the two effects--electronic or structural--is the driving force
Lydia K Nyasae et al.
Traffic (Copenhagen, Denmark), 15(12), 1344-1365 (2014-09-23)
Physiologic Cu levels regulate the intracellular location of the Cu ATPase ATP7B. Here, we determined the routes of Cu-directed trafficking of endogenous ATP7B in the polarized hepatic cell line WIF-B and in the liver in vivo. Copper (10 µm) caused ATP7B
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