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Resmi Anand et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 11(8), 1285-1292 (2012-05-12)
The association of doxorubicin (DOX) and artemisinin (ART) to a β-CyD-epichlorohydrin crosslinked polymer (pβ-CyD), organized in nanoparticles of ca. 15 nm size, was investigated in neutral aqueous medium by circular dichroism (CD), UV-vis absorption and fluorescence. The stability constants and
Epichlorohydrin.
IARC monographs on the evaluation of carcinogenic risks to humans, 71 Pt 2, 603-628 (1999-09-07)
Lina Altomare et al.
Biomatter, 4 (2014-08-06)
Chitosan (CS) is a versatile biopolymer whose morphological and chemico-physical properties can be designed for a variety of biomedical applications. Taking advantage of its electrolytic nature, cathodic polarization allows CS deposition on electrically conductive substrates, resulting in thin porous structures
Amalie E Donius et al.
Journal of the Royal Society, Interface, 10(81), 20120946-20120946 (2013-01-26)
Few studies exist on the mechanical performance of crosslinked electrospun chitosan (CS) fibre mats. In this study, we show that the mat structure and mechanical performance depend on the different crosslinking agents genipin, epichlorohydrin (ECH), and hexamethylene-1,6-diaminocarboxysulphonate (HDACS), as well
Yu Yi et al.
Preparative biochemistry & biotechnology, 42(6), 598-610 (2012-10-04)
Immunoglobulin G (IgG) antibodies are used extensively for analytical, diagnostic, and therapeutic applications. However, there are some disadvantages to purify IgG antibodies by protein A and G affinity chromatography. Therefore, it is necessary to find an effective alternative and nonchromatographic
Celile Demirbilek et al.
Carbohydrate polymers, 90(2), 1159-1167 (2012-07-31)
Epichlorohydrin-crosslinked diethylaminoethyl dextran (DEAE-D/ECH) hydrogel was synthesized by intermolecular side-chain reaction of DEAE-D hydroxyl groups with monomeric crosslinking agent, ECH. Swelling ability, adsorption capacity and metal removal of the hydrogel were profoundly determined and some structural parameters for the hydrogel
Huaxi Xiao et al.
Molecules (Basel, Switzerland), 17(7), 8136-8146 (2012-07-10)
Native rice starch lacks the versatility necessary to function adequately under rigorous industrial processing, so modified starches are needed to meet the functional properties required in food products. This work investigated the impact of enzymatic hydrolysis and cross-linking composite modification
Zahraalsadat Emami Meybodi et al.
Carbohydrate polymers, 92(2), 1792-1798 (2013-02-13)
Curing behavior and gel properties of dextran are investigated during its crosslinking by epichlorohydrin (ECH) using rheometry and equilibrium swelling studies. Each ECH/anhydroglucose unit of different molar ratio (0.16-0.99) was added to a known volume of aqueous dextran solution (25%
Shunyi Li et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 66(11), 2461-2467 (2012-10-04)
An improved drop-sphere-forming (IDSF) method was applied to synthesise chitosan resin. Chitosan resin was synthesised by the self-made device and cross-linked with epichlorohydrin. The influences of concentration of chitosan-acetic acid solution, air flow, reaction time and the dosage of epichlorohydrin
Isabelle Dimier-Poisson et al.
Biomaterials, 50, 164-175 (2015-03-05)
Development of sub-unit mucosal vaccines requires the use of specific delivery systems or immune-modulators such as adjuvants to improve antigen immunogenicity. Nasal route for vaccine delivery by nanoparticles has attracted much interest but mechanisms triggering effective mucosal and systemic immune
Aparna Roy et al.
Carbohydrate polymers, 92(2), 2118-2127 (2013-02-13)
The present work is an endeavor to prepare lignocellulosic biomass based adsorbent, suitable for removal of organic and inorganic pollutants from industrial effluents. Lignocellulosic Corchorus olitorius fibre (jute fibre) surface was grafted with naturally available polyphenol, tannin, preceded by the
Masa-Aki Kawashiri et al.
The American journal of cardiology, 109(3), 364-369 (2011-11-25)
Aggressive low-density lipoprotein (LDL) cholesterol-lowering therapy is important for high-risk patients. However, sparse data exist on the impact of combined aggressive LDL cholesterol-lowering therapy in familial hypercholesterolemia (FH), particularly on side effects to changes in plasma coenzyme Q10 and proprotein
Pilar Aravena et al.
Biotechnology progress, 34(5), 1269-1277 (2018-10-04)
The adsorption of commercial trypsin (Try) onto epichlorohydrin cross-linked alginate-guar gum matrix has been studied at equilibrium in batch and in fixed bed column. Experiments were conducted to study the effect of ionic strength, temperature and to obtain a thermodynamic
Yao Ting Yu et al.
Artificial cells, nanomedicine, and biotechnology, 43(2), 117-123 (2014-05-13)
Spacer can effectively reduce the steric hindrance and synergistic effect of the hydrophilic and hydrophobic ligands immobilized in adsorbents can improve the specific adsorption for low-density lipoprotein (LDL). In this paper, in order to improve the adsorption capacity for the
Hua-Xi Xiao et al.
Molecules (Basel, Switzerland), 17(9), 10946-10957 (2012-09-14)
Rice starch was cross-linked with epichlorohydrin (0.3%, w/w, on a dry starch basis) and oxidized with sodium hypochlorite (2.5% w/w), respectively. Two dual-modified rice starch samples (oxidized cross-linked rice starch and cross-linked oxidized rice starch) were obtained by the oxidation
Seung Ree Seo et al.
International journal of dermatology, 51(8), 987-995 (2012-07-14)
β-Cyclodextrin (βCD) xerogel containing silk fibroin (SF) was prepared, and the efficacy of the xerogel for a pressure sore developed on the back of an ICR mouse was investigated. Tosyl βCD was conjugated to polyethyleneimine (PEI), and the βCD residues
Brittany K Pierce et al.
PloS one, 9(11), e113504-e113504 (2014-11-27)
Xylella fastidiosa is a gram-negative, xylem-limited plant pathogenic bacterium that causes disease in a variety of economically important agricultural crops including Pierce's disease of grapevines. Xylella fastidiosa biofilms formed in the xylem vessels of plants play a key role in
Ornanong S Kittipongpatana et al.
Food chemistry, 141(2), 1438-1444 (2013-06-26)
Cross-linked carboxymethyl rice starches (CL-CMRSs) were prepared from reactions between native rice starch and varied concentrations (0.1-15%w/w, M-0.1 to M-15) of epichlorohydrin (ECH) in a simultaneous carboxymethylation-crosslinking reaction setup using methanol as the solvent. The degree of carboxymethyl substitution was
Huo-Xi Jin et al.
Journal of biosciences, 37(4), 695-702 (2012-08-28)
The enantioselective hydrolysis of racemic epichlorohydrin for the production of enantiopure (S)-epichlorohydrin using whole cells of Aspergillus niger ZJB-09173 in organic solvents was investigated. Cyclohexane was used as the reaction medium based on the excellent enantioselectivity of epoxide hydrolase from
Clinical Environmental Health and Toxic Exposures (2001)
Guang-Peng Wu et al.
Journal of the American Chemical Society, 133(38), 15191-15199 (2011-08-23)
Selective transformations of carbon dioxide and epoxides into biodegradable polycarbonates by the alternating copolymerization of the two monomers represent some of the most well-studied and innovative technologies for potential large-scale utilization of carbon dioxide in chemical synthesis. For the most
Wensheng Lu et al.
The journal of physical chemistry. B, 117(14), 3720-3725 (2013-03-27)
Superparamagnetic Fe3O4 nanoparticles were obtained using a hydrolysis product of starch, i.e., α-d-glucose, as the reducing agent and without any additional stabilizer and dispersant by a facile and green method at mild temperature. Magnetic dialdehyde starch nanoparticles (MDASN) were successfully
A K Giri
Mutation research, 386(1), 25-38 (1997-03-01)
Epichlorohydrin (ECH) is one of the more commercially important aliphatic epoxides used extensively as an industrial intermediate, a laboratory reagent, and as an insecticide. It is a volatile, colourless liquid with an ethereal odour. It behaves as an alkylating agent.
Epichlorohydrin.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man, 11, 131-139 (1976-01-01)
Tatsuya Suzuki et al.
Journal of diabetes and its complications, 26(1), 34-39 (2012-01-14)
The objective was to examine the effects of colestimide on blood glucose, visceral fat, adipocytokines, and bile acid conjugate fractions in Japanese patients. This study was an open-label, randomized, case-control, crossover study of colestimide 3 g/day in 40 Japanese patients
Mitsuhiro Watanabe et al.
PloS one, 7(8), e38286-e38286 (2012-09-07)
Besides well-established roles of bile acids (BA) in dietary lipid absorption and cholesterol homeostasis, it has recently become clear that BA is also a biological signaling molecule. We have shown that strategies aimed at activating TGR5 by increasing the BA
G Bittersohl et al.
Archiv fur Geschwulstforschung, 59(3), 171-175 (1989-01-01)
The aim of this study is the interpretation of the available bibliography concerning the present information about the mutagenic and carcinogenic effects of epichlorohydrin and epoxy resins. An intervention study on 141 exposed workers shows the necessity of an investigation
Study of the crosslinking reaction between epichlorohydrin and starch.
Kuniak L and Marchessault RH.
Starch/Staerke, 24(4), 110-116 (1972)
Mariana Borsoi-Ribeiro et al.
Journal of molecular recognition : JMR, 26(10), 514-520 (2013-09-03)
Iminodiacetic acid (IDA) and tris(2-aminoethyl)amine (TREN) chelating ligands were immobilized on poly(ethylene vinyl alcohol) (PEVA) hollow-fiber membranes after activation with epichlorohydrin or butanediol diglycidyl ether (bisoxirane). The affinity membranes complexed with Cu(II) were evaluated for adsorption of human immunoglobulin G
Tamotsu Neda et al.
Endocrine journal, 59(3), 239-246 (2012-01-11)
Recent studies have shown colestimide, a bile acid-binding resin, to also exert a glucose-lowering effect via amelioration of insulin resistance. To evaluate the effects of colestimide on glucose metabolism and to elucidate the underlying mechanism, we conducted a 6-month, open-label
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