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关键词:'469300'
显示 1-30 共 379 条结果 关于 "469300" 范围 论文
Christophe Provin et al.
Pharmaceutical research, 32(8), 2704-2712 (2015-03-01)
Percutaneous absorption assays of molecules for pharmaceutical and cosmetology purposes are important to determine the bioavailability of new compounds, once topically applied. The current method of choice is to measure the rate of diffusion through excised human skin using a
Sharada Tilve et al.
Scientific reports, 5, 16524-16524 (2015-11-13)
Impaired adult neurogenesis and axon traumatic injury participate in the severity of neurodegenerative diseases. Alpha-synuclein, a cytosolic protein involved in Parkinson's disease, may be released from neurons, suggesting a role for excess secreted alpha-synuclein in the onset and spread of
Majid Ebrahimi Warkiani et al.
Lab on a chip, 15(4), 1101-1109 (2014-12-30)
Diagnosis of malaria at the early stage of infection is challenging due to the difficulty in detecting low abundance parasites from blood. Molecular methods such as real-time polymerase chain reaction (qPCR) can be especially useful for detecting low parasitemia levels
Laurel E Hind et al.
Cytoskeleton (Hoboken, N.J.), 71(9), 542-554 (2014-09-05)
The ability of macrophages to migrate to sites of infection and inflammation is critical for their role in the innate immune response. Macrophage cell lines have made it possible to study the roles of individual proteins responsible for migration using
Anna D Dikina et al.
Biomaterials, 52, 452-462 (2015-03-31)
There is a critical need to engineer a neotrachea because currently there are no long-term treatments for tracheal stenoses affecting large portions of the airway. In this work, a modular tracheal tissue replacement strategy was developed. High-cell density, scaffold-free human
Chiara Ingrosso et al.
ACS applied materials & interfaces, 7(28), 15494-15505 (2015-07-08)
A novel UV-light-curable nanocomposite material formed of a methacrylic-siloxane resin loaded with 1 wt % oleic acid and 3-(trimethoxysilyl)propyl methacrylate silane (OLEA/MEMO)-coated TiO2 nanorods (NRs) has been manufactured as a potential self-curing structural coating material for protection of monuments and
Nancy K Drew et al.
PLoS computational biology, 11(4), e1004190-e1004190 (2015-04-08)
In biology, organization at multiple scales potentiates biological function. Current advances in staining and imaging of biological tissues provide a wealth of data, but there are few metrics to quantitatively describe these findings. In particular there is a need for
Manuela Reitz et al.
Analytica chimica acta, 854, 47-60 (2014-12-07)
This article reports on the chemical analysis of molecular profiles of tarsal secretions of the desert locust Schistocerca gregaria (Forsskål, 1775) by gas chromatography hyphenated with quadrupol mass spectrometry (GC-MS) as well as (1)H-nuclear magnetic resonance ((1)H NMR) spectroscopy. Special
Yamin Yang et al.
Lab on a chip, 15(3), 735-744 (2014-11-28)
In recognition of the limitations of monolayer cell cultures and resource-intensive animal studies, a microfluidic culture system was developed for creation of physiologically relevant three-dimensional (3D) tissues. In this study, an in vitro 3D breast cancer tissue model was established
Ilaria De Pasquale et al.
Applied and environmental microbiology, 80(19), 6243-6255 (2014-08-03)
Pyrosequencing of the 16S rRNA targeting RNA, community-level physiological profiles made with Biolog EcoPlates, proteolysis, and volatile component (VOC) analyses were mainly used to characterize the manufacture and ripening of the pasta filata cheese Caciocavallo Pugliese. Plate counts revealed that
Ana L de Toffoli et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 50(11), 753-759 (2015-09-12)
A method for the identification and quantification of pesticide residues in water, soil, and sediment samples has been developed, validated, and applied for the analysis of real samples. The specificity was determined by the retention time and the confirmation and
M S Abu-Darwish et al.
Journal of ethnopharmacology, 174, 153-160 (2015-08-19)
Artemisia herba-alba Asso ("desert wormwood" in English; "armoise blanche" in French; "shaih" in Arabic), is a medicinal and strongly aromatic plant widely used in traditional medicine by many cultures since ancient times. It is used to treat inflammatory disorders (colds
Bin Li et al.
Small (Weinheim an der Bergstrasse, Germany), 11(28), 3494-3501 (2015-03-20)
A caterpillar-mimetic bilayer actuator is reported, based on a wrinkled polydimethylsiloxane elastomer decorated with a hydroresponsive polyelectrolyte brush. The actuator can fold ultrafast into complex three-dimensional structures upon a change in relative humidity of the surrounding air. The folding direction
Vilma Kaškonienė et al.
Phytochemistry, 115, 184-193 (2015-03-03)
Due to the wide spectrum of biological activities, Chamerion angustifolium L. as medicinal plant is used for the production of food supplements. However, it should be kept in mind that quality (biological activity) of the herb depends on its geographic
Ali Es-Haghi et al.
Talanta, 128, 231-236 (2014-07-26)
Sol-gel based solid-phase microextraction fibers supported by a stainless steel wire were fabricated and employed for GC-MS determination of oxadiargyl in real samples. The fibers were based on four compounds with different polarity: polar and non-polar (end-capped) poly(dimethylsiloxane) (PDMS), polyethylene
Juan Zheng et al.
Nanoscale, 7(27), 11720-11726 (2015-06-24)
Development of facile and effective methods for fabrication of high-performance solid phase microextraction (SPME) fibres remains a great challenge. Herein, a new class of ordered mesoporous polymers (OMPs) in situ coated on a stainless steel wire were successfully developed and
O Carrión et al.
Nature communications, 6, 6579-6579 (2015-03-26)
The volatile compound dimethylsulphide (DMS) is important in climate regulation, the sulphur cycle and signalling to higher organisms. Microbial catabolism of the marine osmolyte dimethylsulphoniopropionate (DMSP) is thought to be the major biological process generating DMS. Here we report the
Yan Man et al.
Journal of separation science, 38(2), 339-345 (2014-11-08)
The polydimethylsiloxane microfluidic chip grafted with poly(N-isopropylacrylamide-3-acrylamidephenylboronic acid) (P(NIPAAm-co-AAPBA)) was fabricated by UV-induced grafting polymerization for the capture-release of cis-diol-containing biomolecules by temperature-modulated changes instead of changing the pH value of the mobile phase. Based on the optimal time for
Encheng Li et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 9(8), 1091-1100 (2014-08-27)
Heavy cigarette smoking-related chronic obstructive pulmonary disease is an independent risk factor for lung squamous carcinoma. However, the mechanisms underlying the malignant transformation of bronchial epithelial cells are unclear. In our study, human tumor-adjacent bronchial epithelial cells were obtained from
Y Zhao et al.
Meat science, 107, 57-63 (2015-05-08)
Dry-cured hams often become infested with ham mites (Tyrophagus putrescentiae) during the aging process. Methyl bromide has been used to fumigate dry cured ham plants and is the only available fumigant that is effective at controlling ham mite infestations. However
Choong Kim et al.
Biomicrofluidics, 8(6), 066504-066504 (2015-01-15)
Cell encapsulation technology is a promising strategy applicable to tissue engineering and cell therapy. Many advanced microencapsulation chips that function via multiple syringe pumps have been developed to generate mono-disperse hydrogel beads encapsulating cells. However, their operation is difficult and
Christina M A P Schuh et al.
Cells, tissues, organs, 200(5), 287-299 (2015-09-16)
Tissue engineering approaches in nerve regeneration search for ways to support gold standard therapy (autologous nerve grafts) and to improve results by bridging nerve defects with different kinds of conduits. In this study, we describe electrospinning of aligned fibrin-poly(lactic-co-glycolic acid)
Iwona Ziemecka et al.
Lab on a chip, 15(2), 504-511 (2014-11-20)
Pervaporation in a microfluidic device is performed on liquid ternary solutions of hydrogen peroxide-water-methanol in order to concentrate hydrogen peroxide (H2O2) by removing methanol. The quantitative analysis of the pervaporation of solutions with different initial compositions is performed, varying the
Nicholas J Schaub et al.
PloS one, 10(9), e0136780-e0136780 (2015-09-05)
The surface of aligned, electrospun poly-L-lactic acid (PLLA) fibers was chemically modified to determine if surface chemistry and hydrophilicity could improve neurite extension from chick dorsal root ganglia. Specifically, diethylenetriamine (DTA, for amine functionalization), 2-(2-aminoethoxy)ethanol (AEO, for alcohol functionalization), or
Dennis Fiorini et al.
Journal of chromatography. A, 1409, 282-287 (2015-07-27)
Given the importance of short and medium chain free fatty acids (FFAs) in several fields, this study sought to improve the extraction efficiency of the solid-phase microextraction (SPME) of FFAs by evaluating salting out agents that appear promising for this
Jonathan M Zuidema et al.
Biomaterials, 46, 82-94 (2015-02-14)
Developing robust in vitro models of in vivo environments has the potential to reduce costs and bring new therapies from the bench top to the clinic more efficiently. This study aimed to develop a biomaterial platform capable of modeling isotropic-to-anisotropic
Vikram D Kodibagkar et al.
Magnetic resonance in medicine, 55(4), 743-748 (2006-03-01)
19F NMR spin-lattice relaxometry of hexafluorobenzene (HFB) has been shown to be a highly sensitive indicator of tumor oxygenation. In this study hexamethyldisiloxane (HMDSO) was identified as a proton NMR analog, and its potential as a probe for investigating dynamic
R Kramer et al.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 34(4), 745-751 (2014-11-29)
For easy handling and speed of lung diseases diagnostics, approaches based on volatile organic compounds (VOCs), including those emitted by pathogenic microorganisms, are considered but currently require considerable sampling efforts. We tested whether easy-to-handle and fast detection of lung infections
Mingfang Pan et al.
Journal of food science, 80(10), M2272-M2278 (2015-08-27)
In this study, fermentation of Allium chinense bulbs was carried out with Lactobacillus plantarum ZDY 2013. A decrease in pH from 6.8 to 3.5 and a stable lactic acid bacteria population were observed during 7-d fermentation. The total phenolic content
Paola Occhetta et al.
Scientific reports, 5, 10288-10288 (2015-05-20)
The development of in vitro models to screen the effect of different concentrations, combinations and temporal sequences of morpho-regulatory factors on stem/progenitor cells is crucial to investigate and possibly recapitulate developmental processes with adult cells. Here, we designed and validated
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