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469300
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关键词:'469300'
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Tohru Hayakawa et al.
Biomaterials, 25(1), 119-127 (2003-10-29)
Plasma polymerized hexamethyldisiloxane (HMDSO) thin film was deposited onto titanium using a radio-frequency apparatus for the surface modification of titanium. A titanium disk was first polished using colloidal silica at pH=9.8. Plasma-polymerized HMDSO films were firmly attached to the titanium
Kathryn Futrega et al.
Biomaterials, 62, 1-12 (2015-05-27)
Microwell platforms are frequently described for the efficient and uniform manufacture of 3-dimensional (3D) multicellular microtissues. Multiple partial or complete medium exchanges can displace microtissues from discrete microwells, and this can result in either the loss of microtissues from culture
Katharina Weiss et al.
PloS one, 9(6), e98784-e98784 (2014-06-03)
Effective antimicrobial strategies are essential adaptations of insects to protect themselves, their offspring, and their foods from microbial pathogens and decomposers. Larvae of the emerald cockroach wasp, Ampulex compressa, sanitize their cockroach hosts, Periplaneta americana, with a cocktail of nine
Sharada Tilve et al.
Scientific reports, 5, 16524-16524 (2015-11-13)
Impaired adult neurogenesis and axon traumatic injury participate in the severity of neurodegenerative diseases. Alpha-synuclein, a cytosolic protein involved in Parkinson's disease, may be released from neurons, suggesting a role for excess secreted alpha-synuclein in the onset and spread of
Christophe Provin et al.
Pharmaceutical research, 32(8), 2704-2712 (2015-03-01)
Percutaneous absorption assays of molecules for pharmaceutical and cosmetology purposes are important to determine the bioavailability of new compounds, once topically applied. The current method of choice is to measure the rate of diffusion through excised human skin using a
Douglas M Ornoff et al.
Biomaterials, 74, 77-88 (2015-10-09)
Microfabrication technology offers the potential to create biological platforms with customizable patterns and surface chemistries, allowing precise control over the biochemical microenvironment to which a cell or group of cells is exposed. However, most microfabricated platforms grow cells on impermeable
Caterina Maulini-Duran et al.
Bioresource technology, 172, 260-268 (2014-10-02)
In this study, the emissions of volatile organic compounds (VOC), CH4, N2O and NH3 during composting non-source selected MSW, source selected organic fraction of municipal solid wastes (OFMSW) with wood chips as bulking agent (OF_wood) and source selected OFMSW with
Vikram D Kodibagkar et al.
Magnetic resonance in medicine, 55(4), 743-748 (2006-03-01)
19F NMR spin-lattice relaxometry of hexafluorobenzene (HFB) has been shown to be a highly sensitive indicator of tumor oxygenation. In this study hexamethyldisiloxane (HMDSO) was identified as a proton NMR analog, and its potential as a probe for investigating dynamic
Analysis of chemical profiles of insect adhesion secretions by gas chromatography-mass spectrometry.
Manuela Reitz et al.
Analytica chimica acta, 854, 47-60 (2014-12-07)
This article reports on the chemical analysis of molecular profiles of tarsal secretions of the desert locust Schistocerca gregaria (Forsskål, 1775) by gas chromatography hyphenated with quadrupol mass spectrometry (GC-MS) as well as (1)H-nuclear magnetic resonance ((1)H NMR) spectroscopy. Special
María Cordero-Vaca et al.
Analytical and bioanalytical chemistry, 407(16), 4615-4627 (2015-05-01)
Four different crosslinked polymeric ionic liquid (PIL)-based sorbent coatings were evaluated in an automated direct-immersion solid-phase microextraction method (automated DI-SPME) in combination with gas chromatography (GC). The crosslinked PIL coatings were based on vinyl-alkylimidazolium- (ViCnIm-) or vinylbenzyl-alkylimidazolium- (ViBzCnIm-) IL monomers
Choong Kim et al.
Biomicrofluidics, 8(6), 066504-066504 (2015-01-15)
Cell encapsulation technology is a promising strategy applicable to tissue engineering and cell therapy. Many advanced microencapsulation chips that function via multiple syringe pumps have been developed to generate mono-disperse hydrogel beads encapsulating cells. However, their operation is difficult and
Laurel E Hind et al.
Cytoskeleton (Hoboken, N.J.), 71(9), 542-554 (2014-09-05)
The ability of macrophages to migrate to sites of infection and inflammation is critical for their role in the innate immune response. Macrophage cell lines have made it possible to study the roles of individual proteins responsible for migration using
Paola Occhetta et al.
Scientific reports, 5, 10288-10288 (2015-05-20)
The development of in vitro models to screen the effect of different concentrations, combinations and temporal sequences of morpho-regulatory factors on stem/progenitor cells is crucial to investigate and possibly recapitulate developmental processes with adult cells. Here, we designed and validated
Jonathan M Zuidema et al.
Biomaterials, 46, 82-94 (2015-02-14)
Developing robust in vitro models of in vivo environments has the potential to reduce costs and bring new therapies from the bench top to the clinic more efficiently. This study aimed to develop a biomaterial platform capable of modeling isotropic-to-anisotropic
Anna D Dikina et al.
Biomaterials, 52, 452-462 (2015-03-31)
There is a critical need to engineer a neotrachea because currently there are no long-term treatments for tracheal stenoses affecting large portions of the airway. In this work, a modular tracheal tissue replacement strategy was developed. High-cell density, scaffold-free human
Takeshi Hara et al.
Chemistry & biodiversity, 12(2), 248-258 (2015-02-14)
Human body odor, which contains several volatile organic compounds, possesses various odor qualities. To identify key volatile compounds responsible for the common unpleasant odors derived from human axillae and feet, the odor quality and intensity of 118 human axillae and
Alessandra Colombini et al.
Tissue engineering. Part A, 21(3-4), 793-802 (2014-09-23)
The intervertebral disc (IVD) presents a limited self-repair ability and cell-based therapies have been suggested to prevent or treat IVD lesions. Fibrin-based scaffolds as cell carriers are promising candidates in IVD tissue engineering, thanks to their ability to be easily
Sun-Myung Kwon et al.
Journal of chromatography. A, 1407, 216-221 (2015-07-15)
A simple and convenient method to detect fluoride in biological samples was developed. This method was based on derivatization with 2-(bromomethyl)naphthalene, headspace solid phase microextraction (HS-SPME) in a vial, and gas chromatography-tandem mass spectrometric detection. The HS-SPME parameters were optimized
Kai-Jie Kao et al.
Biosensors & bioelectronics, 69, 272-279 (2015-03-17)
Over-expression/amplification of human epidermal growth factor receptors 2 (HER2) is a verified therapeutic biomarker for breast and gastric cancers. HER2 is also served as prognostic biomarker for gastric cancer because HER2 over-expression is associated with a 5-10% increase in cancer
Christian A Di Buduo et al.
Blood, 125(14), 2254-2264 (2015-01-13)
We present a programmable bioengineered 3-dimensional silk-based bone marrow niche tissue system that successfully mimics the physiology of human bone marrow environment allowing us to manufacture functional human platelets ex vivo. Using stem/progenitor cells, megakaryocyte function and platelet generation were
Prisila Mkenda et al.
PloS one, 10(11), e0143530-e0143530 (2015-11-26)
Plants with pesticidal properties have been investigated for decades as alternatives to synthetics, but most progress has been shown in the laboratory. Consequently, research on pesticidal plants is failing to address gaps in our knowledge that constrain their uptake. Some
Marie Marchini et al.
Journal of chromatography. A, 1370, 200-215 (2014-12-03)
The volatile constituents of drug samples derived from Cannabis sativa L. were investigated by means of headspace solid phase microextraction (HS-SPME) and gas chromatography techniques (GC-MS, GC×GC-MS). Samples of cannabis herb and hashish showed clear differences in their volatile chemical
Narjes Allahrabbi et al.
Biomicrofluidics, 9(3), 034110-034110 (2015-07-17)
Assessment of the microbial safety of water resources is among the most critical issues in global water safety. As the current detection methods have limitations such as high cost and long process time, new detection techniques have transpired among which
Nicole Favreau-Farhadi et al.
Journal of food science, 80(10), C2140-C2146 (2015-09-27)
Rosmarinic acid and Epigallocatechin gallate concentrations were studied as natural inhibitors of Maillard browning in glucose/glycine model systems, and in bakery rolls and applesauce. The concentrations of the inhibitors were varied to determine the highest level of inhibition without a
Kenta Shimba et al.
Integrative biology : quantitative biosciences from nano to macro, 7(1), 64-72 (2014-11-25)
Recently, axons have been recognized as computational units in neuronal networks that can change their conduction properties along with their firing. However, little is known about the relationship between spontaneous activity and changes in the conduction velocity due to lack
Na Li et al.
Cellular and molecular life sciences : CMLS, 72(15), 2973-2988 (2015-03-27)
Influenza viruses account for significant morbidity worldwide. Inflammatory responses, including excessive generation of reactive oxygen and nitrogen species (RONS), mediate lung injury in severe influenza infections. However, the molecular basis of inflammation-induced lung damage is not fully understood. Here, we
Ágnes M Móricz et al.
Journal of chromatography. A, 1422, 310-317 (2015-10-27)
Two tansy (Tanacetum vulgare L.) essential oils were obtained by steam distillation of the capitula with subsequent liquid-liquid extraction (oil 1) or with use of an auxiliary phase for the trapping of the steam components (oil 2). These oils were
Rui Zhang et al.
Biomedical chromatography : BMC, 29(10), 1492-1498 (2015-03-12)
The abundant production of methyl tert-butyl ether (MTBE) and its widespread use have led to an increase in the potential for human exposure. This work described a simple, fast, sensitive, reliable and low-cost method for the simultaneous measurement of MTBE
Alexandra J Dickinson et al.
Analytical and bioanalytical chemistry, 406(27), 7027-7036 (2014-07-02)
Sphingosine kinase (SK) is a promising therapeutic target in a number of cancers, including leukemia. Traditionally, SK has been measured in bulk cell lysates, but this technique obscures the cellular heterogeneity present in this pathway. For this reason, SK activity
Cheng Guo Li et al.
Lab on a chip, 15(16), 3286-3292 (2015-07-21)
The development of real-time innocuous blood diagnosis has been a long-standing goal in healthcare; an improved, miniature, all-in-one point-of-care testing (POCT) system with low cost and simplified operation is highly desired. Here, we present a one-touch-activated blood multidiagnostic system (OBMS)
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