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关键词:'497-30-3'
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Yin Xie et al.
Medical oncology (Northwood, London, England), 31(3), 844-844 (2014-01-28)
Checkpoint kinase 1 (CHEK1) is an evolutionarily conserved Ser/Thr kinase, which mediates cell-cycle arrest after DNA damage, and we previously reported that CHEK1 was overexpressed and associated with poor prognosis in hepatocellular carcinoma (HCC), indicating it was oncogenic gene. In
Y Suzuki et al.
Journal of biochemistry, 108(3), 344-346 (1990-09-01)
Four overlapping cDNA clones encoding contrapsin were isolated from a mouse liver cDNA library constructed in the expression vector, lambda gt11. M13 vector sequence analysis revealed that contrapsin cDNA contained an open reading frame of 1,254 bases encoding 418 amino
C P Saint et al.
Journal of bacteriology, 175(16), 5205-5215 (1993-08-01)
Rhizopines are selective growth substrates synthesized in nodules only by strains of rhizobia capable of their catabolism. We report the isolation and study of genes for the synthesis and catabolism of a new rhizopine, scyllo-inosamine (sIa), from alfalfa nodules induced
D A Fahey et al.
Biochemistry, 25(15), 4468-4472 (1986-07-29)
Stereospecific 1,2-dipalmitoyl-sn-glycerol and a series of 1,2-dipalmitoyl-3-acyl-sn-glycerols (TGs) with 3-acyl chains of two through six and eight carbons in length were synthesized. Pressure-area isotherms at 27 degrees C, surface melting temperatures (Ts), and equilibrium spreading pressures (esp) measured at the
P Ramos-Mozo et al.
Atherosclerosis, 221(2), 544-550 (2012-02-14)
Cytokines are important mediators of immune-inflammatory responses implicated in abdominal aortic aneurysm (AAA) pathogenesis. Our objective was to investigate the cytokine expression profile in plasma of AAA patients. Cytokine protein expression was measured in plasma of 5 large AAA patients
Myung-Ju Ahn et al.
Human genetics, 131(3), 365-372 (2011-08-26)
The proportion of never smoker non-small cell lung cancer (NSCLC) in Asia is about 30-40%. Despite the striking demographics and high prevalence of never smoker NSCLC, the exact causes still remain undetermined. Although several genome wide association (GWA) studies were
Isabelle Thomassin-Naggara et al.
Radiology, 267(2), 432-443 (2013-03-08)
To construct and undertake preliminary validation of a magnetic resonance (MR) imaging scoring system designed for use in pelvic MR imaging performed for characterization of adnexal masses that were indeterminate at ultrasonography (US). The institutional ethics committee approved this retrospective
R Sato et al.
The Journal of biological chemistry, 269(25), 17267-17273 (1994-06-24)
Transcription of the low density lipoprotein receptor gene and other sterol-regulated genes is stimulated by sterol regulatory element-binding protein-1 (SREBP-1), a basic-helix-loop-helix-leucine zipper (bHLH-ZIP) transcription factor. Human SREBP-1 is synthesized as an 1147-amino acid precursor that is attached intrinsically to
U Savas et al.
The Journal of biological chemistry, 269(21), 14905-14911 (1994-05-27)
A novel benz[a]anthracene and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible cytochrome P-450 (P450EF), which is very active in polycyclic aromatic hydrocarbon metabolism, has been purified from C3H10T1/2 mouse embryo fibroblasts (Pottenger, L. H., Christou, M., and Jefcoate, C. R. (1991) Arch. Biochem. Biophys. 286
S Celik et al.
Acta cardiologica, 56(1), 1-6 (2001-04-21)
The genetic defect of coagulation factor V, known as factor V Leiden, produces a resistance to degradation by activated protein C (APC) and increases the risk of venous thrombosis. However, the role of factor V Leiden in the formation of
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